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1. COMPARISON OF THE EFFECTS OF CIMETIDINE AND TRAMADOL ON THE DISPOSITION OF PARACETAMOL IN HEALTHY HUMAN VOLUNTEERS

ABSTRACT

The influence of cimetidine (400mg) and Tramadol (100mg) on the disposition of oral single dose (1g) Paracetamol was studied and compared in 8 healthy human volunteers under two protocols; concomitant and delayed paracetamol administration. Subjects received one treatment at ea...

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