1. ASSESSMENT OF DIETARY PATTERN AND NUTRITIONAL STATUS OF PEOPLE LIVING WITH HIV/AIDS ATTENDING SOME VOLUNTARY AND COUNSELLING TEST (VCT) UNITS
ABSTRACT
This study assessed the dietary pattern and nutritional status of People Living with HIV/AIDS (PLWHA) attending some voluntary and counseling test units in Kaduna metropolis.The studied subjects consisted of 74 adult patients infected with HIV between the ages...
2. ASSESSMENT OF MICRONUTRIENTS IN CHILDREN WITH MALARIA INFECTION
ABSTRACT
The increased clinical state of malaria infection may be due to poor nutritional status most especially as a result of micronutrients deficiency. Micronutrients play vital role both in combating anaemia and other adverse effects of ma...
3. CONTROLLED RELEASE FORMULATIONS OF ANTIRETROVIRAL (ARV) DRUGS USING POLYMETHACRYLATE POLYMERS
ABSTRACT
To improve patient compliance and ensure better success in the management of HIV, spansule technology was employed to formulate controlled release dosage drug. Generic forms of seven of the most commonly used Anti-retro viral (ARV) drugs (didanosine, indinavir, lamivudine, nelf...
4. COMPARATIVE BIOEQUIVALENCE STUDIES OF SOME SELECTED BRANDS OF CIPROFLOXACIN TABLETS MARKETED IN NIGERIA
ABSTRACT
Comparative bioequivalence studies of six selected brands of ciprofloxacin tablets was successfully conducted. In-vitro quality control studies were carried out on six randomly selected brands of ciprofloxacin to establish identity, weight uniformity, friability, crushing stren...
5. COMPARATIVE IN-VITRO BIOEQUIVALENCE STUDIES OF DIFFERENT SAMPLES OF TINIDAZOLE TABLETS
ABSTRACT
Health care professionals are faced with a large number of multisource products from which therapeutically equivalent products are being selected for various reasons. Consequently, an increased availability and use of generic products has been seen during the last four decades....
6. COMPARATIVE EVALUATION OF THE ASCORBIC ACID CONTENT OF MINERAL ASCORBATE AND ASCORBIC ACID TABLETS MARKETED IN ZARIA
ABSTRACT
The ascorbic acid content of mineral ascorbate and six brands of ascorbic acid tablets marketed in Zaria with brand names Calcium ascorbate, Ascorbion, Emvit C, Ascorvite, Topcee, Bioracee and Sofa C respectively were comparatively evaluated using four methods. These include ti...
7. COMPARATIVE IN-VITRO BIOEQUIVALENCE STUDIES OF SOME BRANDS OF METRONIDAZOLE TABLET MARKETED IN ZARIA, KADUNA STATE
ABSTRACT
Metronidazole is an antibacterial and antiprotozoal drug used in the treatment of amebiasis, giardiasis, trichomoniasis and other microbial diseases. It is an essential drug commonly found in Nigerian market and has so many generics and dosage forms under various trade names by...
8. DRUG MANAGEMENT AND MICRONUTRIENT LEVELS IN ADULT PATIENTS WITH SICKLE CELL DISEASE IN AHMADU BELLO UNIVERSITY TEACHING HOSPITAL SHIKA, ZARIA
ABSTRACT
Sickle cell diseases (SCD) have numerous complications which vary widely among patients making drug treatment difficult. In addition, SCDs are associated with deficiencies in some micronutrients; supplementation of which may ameliorate some of the complications and contribute t...
9. HEPATOPROTECTIVE AND WOUND HEALING PROPERTIES OF METHANOLIC STEM BARK EXTRACT OF FICUS PLATYPHYLLA Del. Holl (MORACEA)
ABSTRACT
Ficus platyphylla (Fp) is a medicinal plant that is widely used in Northern part of Nigeria for the management of skin problems such as eczema and topical application of its gum (latex) to wounds. It is also used for treating malaria and psychosis. Its antioxidant, hepatoprotec...
10. DETERMINATION OF LEAD AND CADMIUM IN SOME HERBAL PREPARATIONS SOLD BY HAWKERS IN NIGERIA AND ENVIRONS
ABSTRACT
Most people administer herbal preparations of different types without considering their side effects. Six sites were selected for the study based on the frequency of consumption. The areas were Kofar Doka, Danmagaji, Tudunwada, Sabongari, Kwangila and Samaru. Five different sam...
11. DEVELOPMENT AND VALIDATION OF THREE NEW SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF LAMIVUDINE IN PURE AND PHARMACEUTICAL DOSAGE FORMS
ABSTRACT
In this study three rapid, simple, accurate, economical and reproducible spectrophotometric methods for the quantitative determination of lamivudine in pure form and tablet formulations were developed and validated. The first method is based on dissolution of standard lamivudin...
12. DEVELOPMENT AND VALIDATION OF FOUR NEW UVSPECTROMETRIC METHODS FOR THE DETERMINATION OF ISONIAZID (INH) IN PURE AND TABLET DOSAGE FORMS
ABSTRACT
Tuberculosis (TB) is a serious infectious disease which is on increase since emergence of human immunodeficiency virus (HIV) leading to TB/HIV co infection, causing complications and treatment failure. Isoniazid is a first line drug for the treatment of TB therefore it is impor...
13. LEAD CONTENT OF SOME FOOD ITEMS SOLD BY HAWKERS IN ZARIA METROPOLIS
ABSTRACT
This study determined lead concentrations in seven types of food sold by hawkers in Zaria and environs. Lead is a heavy metal that serves no useful purpose in the human body. The food samples were coded A –G respectively and the locations were coded A1 – H1. The sam...
14. DEVELOPMENT AND VALIDATION OF SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF RISPERIDONE IN PURE AND TABLET DOSAGE FORMS
ABSTRACT
Two simple, sensitive, accurate and extraction-free spectrophotometric methods were developed and described for the determination of risperidone in pure and in tablet dosage forms. The methods are based on the formation of ion-pair complex between risperidone and the dyes bromo...
15. EFFECT OF GREEN TEA (CAMELLIA SINENSIS) ON THE PHARMACOKINETIC PROFILE OF CEPHALEXIN IN HEALTHY HUMAN VOLUNTEERS
ABSTRACT
Tea is a herb commonly consumed globally. Herbs are often taken concurrently with conventional medicines which results in increased potential of drug-herb interactions, and this may have important clinical significance based on an increasing number of reports of such interactio...
16. EFFECT OF RANITIDINE ON PHARMACOKINETIC PARAMETERS OF METRONIDAZOLE IN HEALTHY HUMAN VOLUNTEERS
ABSTRACT
Pharmacokinetics is the study of the time course of drug movement in the body during absorption, distribution, metabolism and elimination.Drug interactions are pharmacodynamic, pharmacokinetic, or clinical responses to the administration of a drugcombination that differs from t...
17. SPECTROPHOTOMETRIC DETERMINATION AND STABILITY STUDIES OF ARTEMETHER IN ARTEMETHER-LUMEFANTRINE SUSPENSIONS MARKETTED IN NIGERIA
ABSTRACT
The increasing use of artemether-lumefantrine combination as an effective treatment for resistant malaria demands the need for analytical methods for the quality control of these drugs in tablets and suspensions. Though some UV Spectrophotometric methods have been developed for...
18. NUTRITIONAL EVALUATION OF CEREAL AND LEGUME-BASED COMPLEMENTARY DIETS USED IN JOS, PLATEAU STATE
ABSTRACT
Three multimix complementary diets were prepared from local foodstuffs i.e. maize (Zea mays), acha grain (Digitaria exilis) rice (Sativa oryza), sorghum (Sorgum bicolar), millet (Pennisatum typhoides), groundnut (Arachis hypogea), bambaranut (V-oadzeia subterranea), sesame (Ses...
19. ANALYSIS OF PETROLEUM POLLUTION ON SERUM TRACE ELEMENT LEVEL, OXIDATIVE STATUS, AND BIOCHEMICAL INDICES IN THE RESIDENTS OF AN OIL HOST COMMUNITY (UGBEGUNGUN) IN DELTA STATE, NIGERIA
ABSTRACT
Activities of crude oil refining disrupt natural ecosystems which expose residents to environmental pollution, and consequently pose threat to their health and wellness. This study was aimed to analyze serum trace elements levels, oxidative status, and biochemical indices in th...
20. ASSESSMENT OF POLLUTION STATUS OF IMO RIVER, SOUTH EASTERN NIGERIA
ABSTRACT
Globally the environment has been over the years faced with the challenge natural and anthropogenic waste management which affects water, sediment, fish and humans. These issues necessitated this work aimed at assessing the pollution status of upper part of Imo River, South Eas...
