1. EFFECT OF VITAMINS C AND E ON MEMORY IN ADULT MICE
Vitamin C, also known as L-ascorbic acid, is a water-soluble vitamin that is naturally present in some foods, added to others, and available as a dietary supplement and is destroyed by heat or reduced by prolonged storage (Weinstein et al., 2001). Humans, unlike most...
2. ASSESSMENT OF DIETARY PATTERN AND NUTRITIONAL STATUS OF PEOPLE LIVING WITH HIV/AIDS ATTENDING SOME VOLUNTARY AND COUNSELLING TEST (VCT) UNITS
ABSTRACT
This study assessed the dietary pattern and nutritional status of People Living with HIV/AIDS (PLWHA) attending some voluntary and counseling test units in Kaduna metropolis.The studied subjects consisted of 74 adult patients infected with HIV between the ages...
3. FASTING BLOOD SUGAR ANALYSIS AND BLOOD SUGAR REGULATION
ABSTRACT
The investigation carried out of Emmanuel Hospital Eket in Eket Local Government Area Akwa Ibom State. Random sampling technique of 20 patient with equal ration to male and female.
This research to was conducted to determine or estimate the gluco...
4. HEPATITIS B (HBV) SEROLOGICAL MARKERS RELATIONSHIP WITH VITB12 DEFICIENCY
Background of the study
Hepatitis B virus (HBV) is one of the most common chronic infections worldwide and the leading cause for hepatocellular carcinoma (HCC) worldwide.Based on WHO (2012) report, one‐third of the world population estimated a...
5. EVALUATION OF SERUM PROTEIN LEVELS AND CIC LEVELS IN PATIENTS WITH CEREBRAL MALARIA
INTRODUCTION
Globally, Malaria is likely one of the first illnesses known to humans and has had a significant influence on the development of our culture. According to Margret & Suzzan (2019), the history of malaria and the horrific consequences it has on humans go...
6. PHYTOCHEMICAL ANALYSIS OF SELECTED TOMATO PRODUCTS
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INTRODUCTION
INTRODUCTION
Intake of tomato and tomato based-products contributes to the absorption of a wide range of carotenoids in human serum and tissues. The prominent carotenoid in tomatoes is lycopene, a pigment principally responsible for the deep...
7. EVALUATON OF CURRENT TECHNIQUES IN DIAGNOSES OF HUMAN IMMUNODAFICIENCY VIRUS (HIV)
ABSTRACT
A study was carried to ascertain the potency of some techniques used in diagnosis of Human Immunodeficiency virus (HIV). Two hundred and five samples (203) were collected from the patients from the university of Nigerian...
8. DETERMINING THE SERUM PROTEIN LEVELS AND CIC LEVEL IN CEREBRAL MALARIA PATIENTS
OBJECTIVES OF THIS STUDY
This study is aimed at:
- Determining the serum protein levels and CIC level in cerebral malaria patients, those currently on treatments, severe malaria and apparently healthy individuals.
- Comparing the level among th...
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9. ANALYSIS OF SERUM CALCIUM AND PHOSPHORUS IN RICKETS AND NON RICKETS CHILDREN OF GONIN-GORA, KASO AND JANKASA COMMUNITIES IN KADUNA STATE
ABSTRACT
The beginning of the 20th century witnessed the epidemic of nutritional rickets among children in many countries of Asia, North America, Northern Europe and Africa. Nutritional rickets remain a problem in developing countries despite a decline in the prevalence of the condition...
10. CHRONOMODULATED NIFEDIPINE ADMINISTRATION AND MICROVASCULAR COMPLICATIONS IN GLIMEPIRIDE-TREATED HYPERGLYCAEMIC RATS
ABSTRACT
Diabetic complications pose increasing public health problems worldwide. Glimepiride, a sulphonylurea is among the most frequently used anti-diabetic drugs, and is often combined with other drugs for the management of type 2 diabetes mellitus. Nifedipine, a calcium channel bloc...
11. APHRODISIAC AND REPRODUCTIVE STUDIES ON METHANOL ROOT BARK EXTRACT OF SECURINEGA VIROSA (ROXB. EX. WILLD.) BAILL IN MALE WISTAR RATS
ABSTRACT
Securinega virosa (SV) is a widely used plant in traditional medicine. The root is used as an aphrodisiac in north western Nigeria. The aim of the study was to provide pharmacological rationale for the ethnomedical use of the root of Securinega virosa as aphrodisiac as well as...
12. EFFECT OF CHRONOMODULATED ARTESUNATE ON RENAL AND HAEMATOLOGICAL TOXICITY IN CISPLATIN-TREATED WISTAR RATS
ABSTRACT
Cisplatin is a non-cell-cycle dependent chemotherapeutic agent used in the treatment of several common solid tumours. However, an array of serious toxicities in various organs and systems limit its therapeutic use. Artesunate, a semisynthetic derivative of artemisinin is the re...
13. EFFECTS OF ADMINISTRATION OF CARBAMAZEPINE, PHENYTOIN AND THEIR COMBINATION ON NEUROBEHAVIOURAL, COGNITIVE HAEMATOLOGICAL AND SERUM BIOCHEMICAL CHANGES IN ALBINO RATS
ABSTRACT
The aim of the study was to evaluate the neurobehavioural patterns, cognitive functions and haemato-biochemical changes following the administration of carbamazepine (CBZ), phenytoin (PHE) and their combination. Forty, apparently healthy adult male Albino rats weighing between...
14. ETHNOBOTANICAL SURVEY OF PLANTS USED IN TREATMENT OF VIRAL INFECTIONS IN JOS, AND ANTIVIRAL EVALUATIONS OF BOSWELLIA DALZIELLI HUTCH (BURSERACEAE) AND ENANTIA CHLORANTHA OLIVER (ANNONACEAE)
ABSTRACT
An ethnobotanical survey of plants used in the treatment of viral infection was carried out in Jos North, Jos South and Jos East Local Government Areas of Plateau State, Nigeria by verbal interactions with Traditional Medicine Practitioners, Herbalist, Herb sellers and some ind...
15. HYPOTENSIVE ACTIVITY AND TOXICOLOGICAL PROFILE OF STEM BARK EXTRACT OF SYZYGIUM GUINEENSE (Willd, D.C. Myrtaceae) IN LABORATORY ANIMALS
ABSTRACT
Hypertension of unknown cause is called essential or primary hypertension while hypertension of a known cause is called secondary hypertension. Hypertension is called a silent killer because it is usually asymptomatic. It is a global problem affecting 1 in 3 adults in the Unite...
16. PHARMACOLOGICAL INTERACTION BETWEEN ETHANOL EXTRACT OF MORINGA OLEIFERA LEAVES AND METFORMIN IN ALLOXANINDUCED HYPERGLYCAEMIC WISTAR RATS
Abstract
Herbs with anti-diabetic activity could initiate interactions if used concurrently with orthodox drugs. Moringa oleifera is one of such herbs usually taken as an adjunct to orthodox oral hypoglycaemic agents. This study investigated the possible pharmacological interaction betw...
17. PHARMACOTHERAPEUTICS OF MOOD DISORDERS IN PATIENTS ATTENDING NEURO PSYCHIATRIC CLINIC, AHMADU BELLO UNIVERSITY TEACHING HOSPITAL (ABUTH) ZARIA-NIGERIA
ABSTRACT
Mood disorders (primary major depressive disorder and bipolar affective disorder) constitute one of the world’s greatest public health problems and are associated with significant reductions in productivity, health and longevity. This study involved a retrospective analys...
18. TOXICITY AND IMMUNOMODULATORY PROPERTIES OF METHANOL EXTRACT OF THE STEM BARK OF LANNEA ACIDA A. RICH. (ANACARDIACEAE) IN WISTAR RATS
ABSTRACT
Lannea acidaA. Rich.belongs to the family of Anacardiaceae; and the bark, leaves and roots have been reported to possess many medicinal properties, including immunomodulatory activity.Despite this widespread belief, data on the immunomodulatory properties and safety of this pla...
19. TOXICOLOGICAL ASSESSMENT OF THE METHANOL LEAF EXTRACT OF SECURINEGA VIROSA(ROXB EX. WILLD) IN WISTAR RATS
ABSTRACT
Securinega virosa is one of the African medicinal plants described as a true “cure all” among traditional practitioners. Different parts of Securinega virosa have been used in the management of different disorders in Nigeria and other parts of the world. There is th...
20. EFFECTS OF CO-ADMINISTRATION OF SITAGLIPTIN AND ETHANOL LEAF EXTRACT OF MORINGA OLEIFERA LAM. IN ALLOXAN-INDUCED DIABETES MELLITUS AND ITS CHRONIC COMPLICATIONS IN RATS
ABSTRACT
Incidence and prevalence of type 2 diabetes mellitus (T2DM), with its resultant complications continue to be on the increase. The outcome of management is highly dependent on efficacy, safety and suitability of medicines used concomitantly. An aspect of efficacy/safety that is...
21. EFFECTS OF VITAMIN B COMPLEX THERAPY ON TEMPORAL VARIATION IN GENTAMICIN NEPHROTOXICITY IN WISTAR RATS
ABSTRACT
The efficacy and toxicity of several drugs is circadian-rhythm dependent, and this can be exploited as a guide to ameliorate such drug toxicity. Gentamicin is an aminoglycoside antibiotic used in treatment of a variety of infections. Its use is however limited by its associated...
22. HAEMATOLOGICAL, SERUM BIOCHEMICAL AND PATHOLOGICAL CHANGES IN JAPANESE QUAIL (COTURNIX COTURNIX JAPONICA) EXPERIMENTALLY INFECTED WITH SALMONELLA ENTERICA SEROVAR GALLINARUM
ABSTRACT
A total of 160 (108 males and 52 females) Japanese quails (Coturnix coturnix japonica) were used for the experiment. The quails were obtained at the age of four weeks from the Poultry Unit of the National Veterinary Research Institute, Vom, Plateau State, Nigeria. They were ran...
23. SOME NEUROPHARMACOLOGICAL STUDIES ON ETHANOL EXTRACT AND FRACTIONS OF TAPINANTHUS GLOBIFERUS A. RICH MISTLETOE ON VITELLARIA PARADOXA HOST IN LABORATORY ANIMALS
ABSTRACT
Tapinanthus globiferus is a semi-parasite mistletoe which grows on branches of large number of trees including Vitellaria paradoxa. It used locally in the management of insomnia, epilepsy, anxiety, headaches and hypertension. This study evaluated the toxicity and neuropharmacol...
24. THE AMELIORATIVE EFFECT OF ACACIA SIEBERIANA D.C. METHANOL ROOT BARK EXTRACT ON INDUCED LIVER INJURY AND ITS SUBCHRONIC TOXICITY PROFILE IN RATS
ABSTRACT
Acacia sieberiana D.C is traditionally used as a remedy for various ailments including hepatitis. The effect of methanol root bark extract of Acacia sieberiana (ASE) on paracetamol (PCM) - and bile duct ligation (BDL) –induced liver injury wereinvestigated in rats. Rats w...
25. EFFECT OF MICRONUTRIENT SUPPLEMENTATION ON SOME INDICES OF HIV INFECTION PROGRESSION AMONG ANTIRETROVIRAL NAÏVE PATIENTS ATTENDING HIV CLINICS IN NIGERIA
Abstract
Nigeria has the second highest HIV/AIDS burden in the world with an estimated 3,391,546 people living with HIV and AIDS; an estimated 239,155 people acquired new infections in 2013; and about 174,253 people died from AIDS related illness (s) in 2014. HIV infection causes a chro...
26. EVALUATION OF AQUEOUS AND METHANOL ROOT EXTRACTS OF CALOTROPIS PROCERA AIT (ASCLEPIADACEAE) FOR ANTI-ASTHMATIC ACTIVITY ON WISTAR RATS AND GUINEA PIG ILEUM
ABSTRACT
Asthma, which affects an estimated 300 million people worldwide, is an incurable health disorder of a major public health concern globally. The present orthodox therapy for asthma has several drawbacks including many undesirable side effects and high cost of management (especia...
27. PHARMACOLOGICAL EVALUATION OF THREE LOCALLY USED MEDICINAL PLANTS AGAINST CARBON TETRACHLORIDE-INDUCED HEPATOTOXICITY IN RATS
ABSTRACT
Drugs from plant and animal sources are increasingly becoming important in the therapeutic management of liver diseases. This study was undertaken to evaluate the prophylactic and curative effects of methanolic extracts of Balanites aegyptiaca root, Boswellia dalzielii stem bar...
28. ANTIBACTERIAL ACTIVITY OF HELIANTHUS ANNUUS SEEDS EXTRACT ON SALMONELLA SPECIES AND ESCHERICHIA COLI
ABSTRACT Medicinal plants contain active ingredients with therapeutic values. Helianthus annuus L (Asteraceae) commonly referred to as “sunflower” has been reportedly used in managing and treating some ailments over the years. This study investigated the in vitro and in vivo antibacte...
29. ANTI-PLASMODIAL, ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES OF ALKALOID FRACTION OF Maytenus senegalensis LEAF IN MICE
ABSTRACT
The treatment inadequacy and toxicity associated with conventional anti-malarial, antiinflammatory and analgesic drugs calls for the search for alternatives from medicinal plants, particularly. In the present study, alkaloid fraction of Maytenus senegalensis leaf was evaluated...
30. ASSESSMENT OF VARIOUS BIOCHEMICAL CHANGES IN HYPERTENSIVE AND HYPERTENSIVE-PRONE ADULT NIGERIANS IN JOS, NIGERIA
ABSTRACT
A total of 1,075 fasting Human Serum and early morning urine samples were assayed for various biochemical parameters. The parameters include: Blood lipids, Total Cholesterol, High Density lipoproteins, Low Density lipoproteins, Vitamin A, Sodium, Potassium, Chloride, Bicarbonat...
31. THE EFFECT OF N-HEXANE EXTRACT OF KOLA NITIDA BARK ON LIVER FUNCTION TEST OF ALBINO WISTAR RATS FED WITH HIGH FAT FROM COW‘S BRAIN
ABSTRACT
Kola bark extract have been widely used in tradition medicine for thousand of year, it improves liver functions and provides protection against high fat fed metabolic rats. Present investigations were carried out on the hepatoprotective role of Kola bark extract meal treatment...
32. THE EFFECT OF ETHANOL EXTRACT OF DESMODIUM VELUTINUM STEM ON SOME MARKER EMZYME IN LIVER OF ALBINO WISTAR RATS
Abstract
Present investigations were carried out on the effect of ethanol extract of Desmodium velutinum stem on some liver enzymes of albino wistar rats fed with 8 high fat from cow‟s brain. Twelve healthy albino wistar rats were divided into four groups. Group I rats were fed with bal...
33. THE OXIDATIVE STRESS STATUS OF RATS FED ON OIL BEAN SEED MEAL
ABSTRACT
This study was on oxidative stress status of rat fed with Pentraclethra macrophylla, otherwise known as African oil bean seed oil in English or Ugba in Igbo. Sixteen male rats were distributed into four groups. 1 (control), then group 2, 3, and 4 as test groups. They were fed w...
34. COMPARATIVE EFFECT OF COMMERCIAL FEED AND FORMULATED DIETS ON THE GROWTH AND BIOCHEMICAL PARAMETERS OF HETEROBRANCHUS BIDORSALIS (CATFISH) FINGERLINGS
ABSTRACT
Fish farming is a major viable solution to the problem of protein inadequacy in Nigeria but the high cost of feed remains a major obstacle. This study evaluated the comparative effect of commercial feed and formulated diets on the growth and biochemical parameters of Heterobran...
35. IN VIVO EFFICACY OF METHANOLIC EXTRACTS OF ROOT AND LEAF OF Morinda lucida IN Plasmodium berghei - INFECTED MICE
ABSTRACT
Therapeutic effects of the methanolic root extract and a combination of leaf and root extracts of Morinda lucida were evaluated for antiplasmodial activities. The phytochemical screening of the methanolic root extract showed the presence of saponins, flavonoids, alkaloids, phen...
36. ANALYSIS OF PETROLEUM POLLUTION ON SERUM TRACE ELEMENT LEVEL, OXIDATIVE STATUS, AND BIOCHEMICAL INDICES IN THE RESIDENTS OF AN OIL HOST COMMUNITY (UGBEGUNGUN) IN DELTA STATE, NIGERIA
ABSTRACT
Activities of crude oil refining disrupt natural ecosystems which expose residents to environmental pollution, and consequently pose threat to their health and wellness. This study was aimed to analyze serum trace elements levels, oxidative status, and biochemical indices in th...
37. EVALUATION OF SOME NATURAL AND SYNTHETIC PRODUCTS AGAINST AFRICAN TRYPANOSOMIASIS
ABSTRACT
The chemotherapy of African trypanosomiasis, a fatal protozoal disease of man and animals is beset with many problems including a limited repertoire of expensive compounds, drug toxicity and resistance and protracted treatment protocols. In order to improve chemotherapy, some n...
38. THE EFFICACY OF A COMMERCIAL HERBAL FORMULATION IN THE PREVENTION OF COCCIDIOSIS UNDER NATURAL EXPOSURE TO Eimeria SPECIES
ABSTRACT
This study was under taken to determine the Efficacy of a Commercial Herbal Formulation in the Prevention of Coccidiosis under Natural Exposure to Eimeria Species in Animal Production Teaching and Research Farm during the period of March to May 2020. A total of 180 day old broi...
39. EFFECT OF SPROUTING ON THE FORMULATION OF WEANING DIETS FROM BAMBARA NUT (Vigna. subterranean) AND SORGHUM (Sorghum bicolor)
ABSTRACT
Protein energy malnutrition (PEM) accounts for over 50 % mortality among weaning children globally. Fortification and formulation had been used to supply some of the nutritionally deficient nutrients in diets of malnourished children. Sorghum is generally used as weaning foods...
40. NUTRITIONAL ASSESSMENT OF Panicum maximum (Jacq.) ENSILED WITH TWO CULTIVARS OF Lablab purpureus (Lablab purpureus L.) FOR WEST AFRICAN DWARF RAM
ABSTRACT
Panicum maximum, a grass which is low in Crude Protein (CP), high in fibre and scarce in dry periods. Common legumes are used to improve the quality of P. maximum and preserved as hay and silage for dry season feeding. Lablab purpureus is a legume though rich in protein but not...
41. EVALUATION OF CASSAVA (Manihot esculenta Crantz) ROOT PRODUCTS AS REPLACEMENT FOR MAIZE (Zea mays Linn) IN PULLET AND LAYER PRODUCTION
ABSTRACT
Availability of dietary energy is a major problem in poultry in Nigeria. Maize, a conventional energy ingredient is expensive. Cassava, which could be a cheaper alternative energy source, has not been tried in Nigeria. The performance of pullets and layers fed various Cassava R...
42. AN EVALUATION OF EXPANDED PROGRAMME ON IMMUNIZATION AND THE FACTORS INFLUENCING COMMUNITY PARTICIAPTION ( CASE STUDY OF ELIMINA SUB-DISTRICT)
Background Of Study
In community development programs, community engagement now appears to be the "software." Community participation as a developmental strategy is an important cog in the wheel of ensuring that community programs are well-pla...
43. EFFECT OF IONIZING RADIATION ON THE KIDNEY (A CASE STUDY OF WINTER RAT)
Background of the study
The effect of ionizing radiation on biological systems has been a subject of extensive research, particularly concerning its implications on various organs within the body. Among these organs, the kidney holds significant importa...
44. EVALUATON OF CURRENT TECHNIQUES IN DIAGNOSES OF HUMAN IMMUNODAFICIENCY VIRUS (HIV)
ABSTRACT
A study was carried to ascertain the potency of some techniques used in diagnosis of Human Immunodeficiency virus (HIV). Two hundred and five samples (205) were collected from the patients from the university of Nigerian...
45. SERUM LIPID PROFILE OF AFRICA MESQUITE TREE PART EXTRACT IN RAT
ABSTRACT
This study investigates the lipid-modulating effects of extracts from different parts of the African mesquite tree (Prosopis africana) in a rat model. The experiment employed a randomized controlled trial design with four groups: a control grou...
