1. OPTIMIZATION OF BIODIESEL PRODUCTION FROM YELLOW OLEANDER AND CASTOR OILS AND STUDIES OF THEIR FUEL PROPERTIES
Abstract
The optimization of biodiesel production from two non-edible oils and studies of their fuel and biodegradability properties was carried out. The two oil feedstocks (Yellow oleander and Castor oils) were extracted from their seeds using an oil e...
2. PRODUCTION OF DISINFECTANT
ABSTRACT
Disinfectants are antimicrobial agents that are applied to non-living objects to destroy micro-organisms that are living on the object. They are different from other antimicrobial agents like antibiotics which destroys micro-organisms within the body and antise...
3. AN EVALUATION OF THE APHRODISIAC AND FERTILITY ENHANCING EFFECT OF THE METHANOLIC ROOT EXTRACT OF CISSUS POPULNEA Guill.And Perr. (Vitaceae)
ABSTRACT
Aphrodisiac activity of Cissus populnea was assessed using physical, biochemical and psychological methods. Rats were randomized into five groups of six rats. The first group received normal saline (10ml/kg), the second, third and fourth groups received extract doses of 250mg/k...
4. ANALGESIC AND ANTI-INFLAMMATORY EFFECTS OF METHANOL EXTRACT AND FRACTIONS OF LAGGERA AURITA LINN F (COMPOSITAE) IN MICE AND RATS
ABSTRACT
The plant Laggera aurita is an annual or biennial herb of widespread in dry waste places from across Senegal to Southern Nigeria. The plant has been reportedly used for medicinal purposes including treatment of rheumatic pain, healing of cuts and bruises, and as a last resort t...
5. ANALGESIC AND ANTI-INFLAMMATORY STUDIES ON METHANOL ROOT EXTRACT OF ANDROPOGON GAYANUS KUNTH (POACEAE) IN MICE AND RATS
ABSTRACT
The plant Andropogon gayanus is employed in herbal medicine for the treatment of various disease conditions. The dried root of the plant is soaked in milk and taken for the treatment of postpartum pain and bronchitis in North-west Nigeria. In this study the methanol root extrac...
6. ANALGESIC, ANTI-INFLAMMATORY AND OTHER PHARMACOLOGICAL ACTIVITIES OF METHANOL LEAF EXTRACT OF OLAX SUBSCORPIOIDEA OLIV (OLACACEAE) IN LABORATORY ANIMALS
ABSTRACT
Synthetic analgesic and anti-inflammatory drugs have major side effects such as constipation, nausea and vomiting, sedation and mental clouding, etc.,which have significantly limited their use.There is therefore, an intensification of search for newer analgesic and anti-inflamm...
7. ANALGESIC, ANTI-INFLAMMATORY AND TOXICITY STUDIES ON METHANOLIC LEAF EXTRACT OF ROTHMANNIA LONGIFLORA SALISB (RUBIACEAE) IN RATS AND MICE
ABSTRACT
The herbalists in several African Countries have used Rothmannia longiflora decoctions as febrifugal and analgesic agent. The present study examined the analgesic, anti-inflammatory and toxicological profile of the methanolic extract of the plant in experimental animals. The pr...
8. ANTI-DIARRHOEAL AND SUBCHRONIC TOXICITY STUDIES ON METHANOL STEM BARK EXTRACT OF IRIVINGIA WOMBOLU VERMOESEN (IRVINGIACEAE) IN LABORATORY ANIMALS
Abstract
Irvingia wombolu is one of the herbal plants used as food for its nutritional values. It is also used as medicinal plant in the south-south and south-eastern part of Nigeria for the management of diarrhoea and other ailments. Although these medicinal plants are believed to be h...
9. ANTICONVULSANT AND SUB-CHRONIC TOXICITY STUDIES OF THE METHANOL LEAF EXTRACT OF DIOSPYROS MESPILIFORMIS HOCHST (EBENACEAE) IN LABORATORY ANIMALS
ABSTRACT
Diospyros mespiliformis hochst (Ebenaceae) known in English as ebony is a plant that is found throughout West Africa. The Plant was reported to have wide ethnomedical application notably in fever, whooping cough, wounds, pneumonia, syphilis, leprosy and epilepsy among others. T...
10. ANTICONVULSANT STUDIES OF THE METHANOL EXTRACT AND FRACTIONS OF CASSIA SIAMEA LAM. (FABACEAE) IN MICE AND CHICKS
ABSTRACT
Cassia siamea is a shrub belonging to the Fabaceae family, native of Southeast Asia. The plant is commonly used in traditional medicine to treat hypertension, malaria and diabetes. Due to the easy cultivation of the plant, its widespread and also remarkable biological activitie...
11. ANTICONVULSANT STUDIES ON METHANOL LEAF EXTRACT OF LAGGERAAURITA LINN.F.IN LABORATORY ANIMALS
ABSTRACT
LaggeraauritaLinn. belongs to the family of Asteraceae. It is an annual herb which is found growing as weeds in Nigeria and spread throughout the sub-Saharan Africa. In Nigeria, Laggeraaurita is used asa remedy for pediatric malaria and in the management of epilepsy in Niger st...
12. ANTIDIARRHOAEL EFFECT OF METHANOL STEM BARK EXTRACT OF HYMENOCARDIA ACIDA (EUPHOBIACEAE) IN LABORATORY ANIMALS
Abstract
The objective of the present study was to evaluate the antidiarrheal activity of the methanol stem bark extract of Hymenocardia acida in some laboratory animals. They methanol stem bark extract of Hymenocardia acida (MEHA) was prepared from the freshly collected stem bark of th...
13. ANTIDIARRHOEAL AND TOXICITY STUDIES ON METHANOL LEAF EXTRACT OF COMBRETUM HYPOPILINUM DIELS (COMBRETACEAE) IN MICE AND RATS
ABSTRACT
The plant Combretum hypopilinum has been used in traditional medicine to treat diarrhoea and other gastrointestinal diseases. This study aimed to investigate the antidiarrhoeal activity and toxicity profile of the methanol leaf extract of Combretum hypopilinum (MECH) in mice an...
14. ANTIHYPERGLYCAEMIC AND ANTIBACTERIAL EVALUATION OF METHANOL TUBER EXTRACT OF CHLOROPHYTUM ALISMIFOLIUM BAKER (LILIACEAE)
ABSTRACT
Diabetes mellitus is a metabolic disorder which affects about 346 million people globally. Synthetic antidiabetic agents are expensive and also associated with side effects. In a bid to develop cheaper and safer antidiabetic agents, this study was carried out to determine the e...
15. BEHAVIOURAL AND ANTICONVULSANT EFFECTS OF METHANOL EXTRACT OF FICUS VALLIS CHOUDAE (MORACEAE) STEM BARK
ABSTRACT
Ficus vallis choudae is a plant widely spread in tropical Africa including Nigeria. It is said to be of value in ethnomedicine especially in the treatment of jaundice, gastrointestinal problems, giddiness and epilepsy. The anticonvulsant activity of methanol stem bark extract o...
16. APHRODISIAC AND REPRODUCTIVE STUDIES ON METHANOL ROOT BARK EXTRACT OF SECURINEGA VIROSA (ROXB. EX. WILLD.) BAILL IN MALE WISTAR RATS
ABSTRACT
Securinega virosa (SV) is a widely used plant in traditional medicine. The root is used as an aphrodisiac in north western Nigeria. The aim of the study was to provide pharmacological rationale for the ethnomedical use of the root of Securinega virosa as aphrodisiac as well as...
17. ANTI-HYPERLIPIDEMIC POTENTIAL OF VITEX DONIANAETHANOLEXTRACTS ON POLOXAMER 407 INDUCED HYPERLIPIDEMIC AND NORMAL RATS
ABSTRACT
Anti-hyperlipidemic potential of extracts (aqueous, 70% methanol, 70% ethanol and 70%, acetone) of Vitexdoniana leaves, stem bark and root bark on poloxamer 407 induced hyperlipidemic and normal rats was investigated. Phytochemical screening of the extracts revealed the presenc...
18. COMPARATIVE EVALUATION OF THE HYPOTENSIVE EFFECTS OF THE SEED AND LEAF EXTRACTS OF MORINGA OLEIFERA LAM (Moringaceae) IN LABORATORY ANIMALS
ABSTRACT
Moringa oleifera is locally used in Nigeria for the management of respiratory disorders, hypertension and poor blood circulation among other ailments. However, all parts of the plant are blindly used because the exact part of this plant and / or extractive solvent that provides...
19. ETHNOBOTANICAL SURVEY OF PLANTS USED IN TREATMENT OF VIRAL INFECTIONS IN JOS, AND ANTIVIRAL EVALUATIONS OF BOSWELLIA DALZIELLI HUTCH (BURSERACEAE) AND ENANTIA CHLORANTHA OLIVER (ANNONACEAE)
ABSTRACT
An ethnobotanical survey of plants used in the treatment of viral infection was carried out in Jos North, Jos South and Jos East Local Government Areas of Plateau State, Nigeria by verbal interactions with Traditional Medicine Practitioners, Herbalist, Herb sellers and some ind...
20. EVALUATION OF ANTITRYPANOSOMAL EFFECT OF STEM-BARK EXTRACTS OF SECURIDACA LONGEPEDUNCULATA (FRES. HOLL) AGAINST TRYPANOSOMA BRUCEI BRUCEI INFECTION IN WISTAR RATS
ABSTRACT
Due to numerous problems associated with current treatment of trypanosomosis, there is increasing need to find effective drug against trypanosomosis ravaging sub-Saharan Africa from traditional medicinal herbs. This work is aimed at evaluating efficacy of stem-bark extracts of...
21. EVALUATION OF PHARMACOGNOSTICPARAMETERS AND HEPATOTOXIC EFFECTS OF EXTRACTSOF CASSYTHA FILIFORMIS LINN ON PARACETAMOL-INDUCED LIVER DISORDERS IN WISTER RATS
ABSTRACT
Cassytha filiformis, a leafless and perennial vine with small scales as a replacement of the leavesis currently being used in the treatment of various disease conditions including jaundice without standardization.Microscopical evaluation, chromatographic analysis (TLC, HPLC, LC...
22. HEPATOPROTECTIVE AND WOUND HEALING PROPERTIES OF METHANOLIC STEM BARK EXTRACT OF FICUS PLATYPHYLLA Del. Holl (MORACEA)
ABSTRACT
Ficus platyphylla (Fp) is a medicinal plant that is widely used in Northern part of Nigeria for the management of skin problems such as eczema and topical application of its gum (latex) to wounds. It is also used for treating malaria and psychosis. Its antioxidant, hepatoprotec...
23. HYPOTENSIVE ACTIVITY AND TOXICOLOGICAL PROFILE OF STEM BARK EXTRACT OF SYZYGIUM GUINEENSE (Willd, D.C. Myrtaceae) IN LABORATORY ANIMALS
ABSTRACT
Hypertension of unknown cause is called essential or primary hypertension while hypertension of a known cause is called secondary hypertension. Hypertension is called a silent killer because it is usually asymptomatic. It is a global problem affecting 1 in 3 adults in the Unite...
24. PHARMACOGNOSTIC AND ANTIBACTERIAL STUDIES OF THE LEAVES OF CHROMOLAENA ODORATA (L.) KING & ROBINSON (ASTERACEAE)
ABSTRACT
The plant, Chromolaena odorata (L.) King & Robinson is a member of the Asteraceae family. It grows abundantly in Southern Nigeria where its leaves are used as traditional herbal treatment for wounds and fevers. The plant, C. odorata was therefore investigated for antibacter...
25. DEPARTMENT OF PHARMACOGNOSY AND DRUG DEVELOPMENT, FACULTY OF PHARMACEUTICAL SCIENCES, AHMADU BELLO UNIVERSITY ZARIA
Abstract
Carissa edulis and Senna alata are plants found in Nigeria and some other tropical countries. In Nigeria, C. edulis and S. alata are used for the treatment of various ailments and diseases. In traditional medicine C. edulis is used for the treatment of skin infections, abdomina...
26. PHARMACOGNOSTIC AND ANTIVENIN STUDIES ON LEAVES OF SECURINEGA VIROSA (ROXB EX WILLD) BAILL
ABSTRACT
7 Securinega virosa (Roxb ex Willd) Baill (Euphorbiaceae) is a small, deciduous, graceful shrub that is widely distributed in Africa. It is used to treat snakebites, syphilis, rheumatism and malaria. Plant based medicines are limited in use because of inadequate standardization...
27. PHYTOCHEMICAL AND ANTI-INFLAMMATORY STUDIES OF N-BUTANOL SOLUBLE FRACTION OF THE METHANOLIC EXTRACT OF THE AERIAL PARTS OF INDIGOFERA HIRSUTA LINN (LEGUMINOSAE)
Abstract
Indigofera hirsuta Linn. (Leguminosae) is a well-known plant used in African traditional medicine as an anti-inflammatory, antibacterial, antiulcer, anti-venom and anticonvulsant. The air-dried aerial parts of I. hirsuta was extracted with methanol using a soxhlet extractor and...
28. PHYTOCHEMICAL AND ANTIVENOM STUDIES ON THE STEM BARK OF ALBIZIA CHEVALIERI HAMS (MIMOSACEAE) ON NAJA NIGRICOLLIS BROADLEY ENVENOMATED MICE
ABSTRACT
Albizia chevalieri Hams (Mimosaceae), mostly found in the Northern Sahel Savannah region of Nigeria as well as in Nigér and Senegal is a tree of the acacia type with a long list of folklore therapeutic claims which include its use as purgative, taenicidal, cough remedy,...
29. PHYTOCHEMICAL AND SOME BIOLOGICAL STUDIES OF THE METHANOL EXTRACT OF THE AERIAL PARTS OF AMPELOCISSUS GRANTII(BAKER) PLANCH. (VITACEAE)
ABSTRACT
The plant Ampelocissus grantii is used in traditional medicinal practice in the treatment of cough, wounds, venereal infections and other ailments.Phytochemical examination of the methanol extract of the aerial parts of Ampelocissus grantii (Baker) Planch (Family, Vitaceae) rev...
30. PHYTOCHEMICAL AND SOME PHARMACOLOGICAL STUDIES OF THE AERIAL PART OF ALYSICARPUS OVALIFOLIUS Schumach & Thonn FAMILY: FABACEAE
ABSTRACT
Alysicarpus ovalifolius (Schum.&Thonn) Family: Fabaceae is a protein rich fodder plant that is widely distributed across Africa, Asia and Australia and medicinally used to treat cough and wounds. Recently, it has been reported to be used in the Northern part of Nigeria as t...
31. PHYTOCHEMICAL AND SOME PHARMACOLOGICAL STUDIES ON THE LEAF EXTRACT OF ZIZIPHUS MUCRONATA WILLD. (RHAMNACEAE)
ABSTRACT
Chronic inflammation has been implicated in most non-communicable/chronic degenerative diseases including age-related cancers. Ziziphus mucronata, a plant used in ethnomedicine to treat different painful and inflammatory conditions, was subjected to phytochemical investigation...
32. PHYTOCHEMICAL INVESTIGATIONS AND ANTICANCER ACTIVITY STUDIES ON THE LEAVES OF FICUS SYCOMORUS LIN. (FAMILY: MORACEAE)
ABSTRACT
Ficus sycomorous (Family Moraceae) is a plant used in African traditional medicine to treat mental illness, dysentery, cough, diarrhea, tuberculosis and cancer. The aim of this research work is to isolate and characterize some compounds from the leaf of Ficus sycomorous and to...
33. PHYTOCHEMICAL, ANTIHYPERTENSIVE AND ANTIMICROBIAL STUDIES ON THE STEM BARK EXTRACT OF STEREOSPERMUM KUNTHIANUM CHAM (BIGNONIACEAE)
Abstract
Stereospermum kunthianum (Family: Bignoniaceae) plant is used in Hausa ethnomedicine in treating bronchitis, veneral diseases, diarrheoa and dysentery. It is also used in the treatment of ulcers, leprosy, skin eruptions, respiratory ailments, abortifacient, antihypertensive and...
34. PHYTOCHEMICAL, PHARMACOLOGICAL AND FORMULATION STUDIES OF Andrographis paniculata Nee Acanthacae
ABSTRACT
The leaves of Andrographis paniculata acanthaceae is used locally in Northern Nigerian for the treatment of hypertension without quantification or dosage standardization. This work was primarily set out to find justification for the local medicinal use of this plant and to scie...
35. TOXICITY AND IMMUNOMODULATORY PROPERTIES OF METHANOL EXTRACT OF THE STEM BARK OF LANNEA ACIDA A. RICH. (ANACARDIACEAE) IN WISTAR RATS
ABSTRACT
Lannea acidaA. Rich.belongs to the family of Anacardiaceae; and the bark, leaves and roots have been reported to possess many medicinal properties, including immunomodulatory activity.Despite this widespread belief, data on the immunomodulatory properties and safety of this pla...
36. TOXICOLOGICAL ASSESSMENT OF THE METHANOL LEAF EXTRACT OF SECURINEGA VIROSA(ROXB EX. WILLD) IN WISTAR RATS
ABSTRACT
Securinega virosa is one of the African medicinal plants described as a true “cure all” among traditional practitioners. Different parts of Securinega virosa have been used in the management of different disorders in Nigeria and other parts of the world. There is th...
37. TOXICOLOGICAL, ANTIPYRETIC, ANALGESIC AND ANTI-INFLAMMATORY PROPERTIES OF METHANOL LEAF EXTRACT OF DALBERGIA SAXATILIS HOOK. F (FABACEAE) IN RATS AND MICE
ABSTRACT
The decoction of the leaves of Dalbegia saxatilis is used in Traditional Medicine for various ailments such as cough, small pox, skin lesions, bronchial ailments and toothache. The study was aimed at establishing a safety profile, evaluating phytochemical constituents and some...
38. DEVELOPMENT AND VALIDATION OF THREE NEW SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF LAMIVUDINE IN PURE AND PHARMACEUTICAL DOSAGE FORMS
ABSTRACT
In this study three rapid, simple, accurate, economical and reproducible spectrophotometric methods for the quantitative determination of lamivudine in pure form and tablet formulations were developed and validated. The first method is based on dissolution of standard lamivudin...
39. DEVELOPMENT AND VALIDATION OF FOUR NEW UVSPECTROMETRIC METHODS FOR THE DETERMINATION OF ISONIAZID (INH) IN PURE AND TABLET DOSAGE FORMS
ABSTRACT
Tuberculosis (TB) is a serious infectious disease which is on increase since emergence of human immunodeficiency virus (HIV) leading to TB/HIV co infection, causing complications and treatment failure. Isoniazid is a first line drug for the treatment of TB therefore it is impor...
40. DIURETIC AND TOXICITY STUDIES OF METHANOL STEM BARK EXTRACT OF SPONDIAS MOMBIN LINN (ANACARDIACEAE) IN RATS
ABSTRACT
Spondias mombin belongs to the family Anacardiacae. All parts of the tree are reported to be medicinally useful. The fruit juice is drunk as a diuretic and febrifuge. The main aim of the study is to determine the diuretic activity and toxicity of methanol stem bark extract of S...
41. ETHNOBOTANICAL SURVEY OF PLANTS USED FOR THE TREATMENT OF TYPHOID FEVER IN NIGERIA, AND EVALUATION OF ANTI-TYPHOID ACTIVITY OF TERMINALIA AVICENNOIDES GUILL & PERR. (COMBRETACEAE)
ABSTRACT
An ethnobotanical survey was conducted from December 2011 to April 2012 in Minna, Niger State, Nigeria. The survey was aimed at identifying and documenting medicinal plants used for the treatment of typhoid fever in 6 communities in Minna, Niger State and establishing resourcef...
42. EVALUATION OF THE GASTROPROTECTIVE AND SUB-CHRONIC TOXICITY OF METHANOL STEM BARK EXTRACT OF XIMENIA AMERICANA LINN (OLACACEAE) IN MALE WISTAR RATS
Abstract
Ximenia americana is a plant used traditionally in northern parts of Nigeria for treatment of leprotic ulcers and mouth ulcers in addition to other medicinal uses. It contains flavanoids, saponins, tannins among others that has been reported to possess gastroprotective potentia...
43. GASTRO-INTESTINAL MUCOSAL PROTECTIVE PROPERTIES AND TOXICITY STUDIES ON THE METHANOL ROOT EXTRACT OF WALTHERIA INDICA LINN. (STERCULIACEAE) IN LABORATORY ANIMALS
ABSTRACT
Many countries worldwide including Nigeria use different parts of Waltheria indica (leaves, stem-barks, roots and whole plants) to treat various ailments. In Nigeria, Waltheria indica is used to treat gastro-intestinal ulcers, pain, inflammation, diarrhoea, conjunctivitis, anae...
44. PHYTOCHEMICAL AND SOME BIOLOGICAL STUDIES OF THE METHANOL LEAF EXTRACT OF ASPILIA AFRICANA (PERS.) C. D. ADAMS (ASTERACEAE)
Abstract
Aspilia africana, (Pers) C.D. Adams; (Asteraceae), a semi perennial woody plant, commonly known as haemorrhage plant is widely distributed across tropical Africa and all parts of Nigeria. The plant is well known in folkloric medicine for its anti-haemorrhagic uses and for the t...
45. MEDICINAL PLANTS USED IN THE MANAGEMENT OF DEPRESSIVE ILLNESSES: ANTIDEPRESSANT ACTIVITY OF METHANOL STEM BARK EXTRACT OF ADANSONIA DIGITATA L. IN MICE
ABSTRACT
Depression is a heterogeneous mood disorder that has been treated with a number of synthetic drugs. These drugs have adverse effects and delayed onset of action that compromise their therapeutic benefits. This makes it worthwhile to search for new antidepressant agents with pro...
46. PHARMACOGNOSTIC AND ANTIMICROBIAL STUDIES OF THE STEM BARK OF FICUS THONNINGII BLUME (MORACEAE)
ABSTRACT
Ficus thonningii Blume is a popular medicinal plant used in Nigeria for the treatment of various ailments including diarrhoea, pneumonia, sore throat and typhoid. Physicochemical, macroscopic, microscopic, phytochemical and antimicrobial evaluations of the stem bark of the plan...
47. PHARMACOGNOSTIC, NUTRITIONAL AND TOXICITY STUDIES ON THE AERIAL PART OF DAUCUS CAROTA L. (APIACEAE)
Abstract
Daucus carota (L.) commonly known as carrot belongs to the family of Apiaceae. The aerial part is used as component of livestock feed in some part of Northern Nigeriawithout any scientific evidence ofsafety. The present study was carried out to establish its pharmacognostic, nu...
48. PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE METHANOL EXTRACT OF ACACIA ATAXACANTHA LEAF D.C. (LEGUMINOSAE) IN MICE AND RATS
ABSTRACT
Acacia ataxacantha is used in traditional medicine for management of pain and inflammation. Literature survey revealed that the safety and efficacy of such uses have not been scientifically validated. The present study was designed to study the pharmacological and toxicological...
49. PHYTOCHEMICAL AND SOME PHARMACOLOGICAL STUDIES OF THE LEAF OF OCHNA RHIZOMATOSA (VAN TIEGH.) KEAY [OCHNACEAE]
ABSTRACT
The extract of the leaf of Ochna rhizomatosa (van Tiegh.) Keay [Ochnaceae], a plant used in the treatment of malaria in Northern Cameroun, was subjected to preliminary phytochemical screening. The result revealed the presence of carbohydrates, steroids, cardiac glycosides, terp...
50. PHYTOCHEMICAL AND ANTICONVULSANT STUDIES OF METHANOL LEAF EXTRACT OF HYMENOCARDIA ACIDA, TUL (EUPHORBIACEAE)
ABSTRACT
The research was on the phytochemical and anticonvulsant studies of methanol leafextract of Hymenocardia acida, Tul, (Euphorbiaceae) used inNorthern Nigeria for the treatment of headache, rheumatic pain, sickle cell crisis, malaria, epilepsy and cancer. The preliminary phytoche...
