1. FEVER AS A PREDICTOR FOR MALARIA INFECTION AMONG INDIVIDUALS ATTENDING KOFAI PHCC IN ARDO-KOLA LGA TARABA STATE
BACKGROUND OF STUDY
Malaria is a life threatening parasitic disease transmitted by female Anopheles mosquitoes. In Nigeria, malaria is responsible for around 60% of the out-patient visits to health facilities, 30% of childhood death, 25% of death in children under one y...
2. A COMPARATIVE STUDY ON HEALTH EDUCATION INTERVENTION ON MALARIA PREVENTION IN COMMUNITIES
EXCERPT FROM THE STUDY
The study concludes that health education intervention has improved the knowledge of the mothers about the various malaria prevention strategies among the nursing mothers with non-significant change in attitude.
Caregivers acted promptly...
3. AWARENESS OF THE USE OF ENVIRONMENTAL MANAGEMENT IN THE CONTROL AND PREVENTION OF MALARIA
Background To the study
The vast majority of malaria deaths occur in Africa, south of the Sahara, where malaria also presents major obstacles to social and economic development. Malaria has been estimated to cost Africa more than US$ 12 billion every ye...
4. A STATISTICAL REVIEW OF MALARIA CASES AMONG CHILDREN AND ADULT
Background of the study
The Malaria remains one of the most serious global health problems. There are an estimated one million deaths each year, with nearly seventy five percent (75%) occurring in children living in sub-Saharan Africa. The history of malaria stretc...
5. AN ANTIMICROBIAL ANALYSIS AND PHYTOCHEMICAL OF Mangifera indica AND Carica papaya LEAVES
BACKGORUND TO THE STUDY
It is well known that in order for a plant to protect itself, it creates certain compounds that can also protect humans from sickness. Today, there are approximately 4000 distinct phytochemicals that have the potential to alter disorders such as...
6. DESIGN, SYNTHESIS, ANTIMALARIAL EVALUATION AND COMPUTATIONAL STUDIES OF SOME CHALCONE DERIVATIVES
ABSTRACT
Inspired by the previous findings on the structural requirements needed for good antimalarial activity by chalcones against Plasmodium proteases, seventeen chalcone derivatives were designed and synthesized using Claisen-Schmidt condensation of appropriate aldehydes and methyl...
7. ANTIMALARIAL SUSCEPTIBILITY AND DRUG RESISTANCE CHARACTERIZATION STUDIES OF PLASMODIUM SPECIES ISOLATES FROM PATIENTS IN NIGERIA
ABSTRACT
About half of Nigerian population experience at least one episode of malaria per year, resulting in high morbidity and mortality and loss of economic value. Retrospective study of the profile of malarial patients and the antimalarial drugs prescribed at Umaru Musa Yaradua memor...
8. STUDY ON THE EFFICACY AND SAFETY OF ARTEMETHER/LUMEFANTRINE IN THE TREATMENT OF UNCOMPLICATED PLASMODIUM FALCIPARUM MALARIA AMONGST CHILDREN IN NIGERIA
ABSTRACT
Globally, malaria is a major health concern because it causes high morbidity and mortality particularly in children under 5 years because of their low immunity. The development of resistance to chloroquine and sulphodoxine/pyrimethamine in many parts of the world has further wo...
9. EFFECTS OF ANTIMALARIAL DRUGS ON OESTROUS CYCLE AND UTERINE CONTRACTILITY IN RATS
ABSTRACT
Malaria is increasingly a health burden globally with children under the age of 5 and pregnant women being the most vulnerable. Several antimalarials are available in the market today however; the safety data in pregnancy is inadequate especially the first trimester of pregnanc...
10. PHYTOCHEMICAL AND SOME BIOLOGICAL STUDIES OF THE METHANOL LEAF EXTRACT OF ASPILIA AFRICANA (PERS.) C. D. ADAMS (ASTERACEAE)
Abstract
Aspilia africana, (Pers) C.D. Adams; (Asteraceae), a semi perennial woody plant, commonly known as haemorrhage plant is widely distributed across tropical Africa and all parts of Nigeria. The plant is well known in folkloric medicine for its anti-haemorrhagic uses and for the t...
11. PHYTOCHEMICAL AND SOME PHARMACOLOGICAL STUDIES OF THE LEAF OF OCHNA RHIZOMATOSA (VAN TIEGH.) KEAY [OCHNACEAE]
ABSTRACT
The extract of the leaf of Ochna rhizomatosa (van Tiegh.) Keay [Ochnaceae], a plant used in the treatment of malaria in Northern Cameroun, was subjected to preliminary phytochemical screening. The result revealed the presence of carbohydrates, steroids, cardiac glycosides, terp...
12. THE EFFECT OF MEFLOQUINE CHEMOPROPHYLAXIS ON THE OUTCOME OF PREGNANCY IN WOMEN OF LOW AND HIGH PARITY IN NIGERIA
ABSTRACT
Malaria accounts for 25% -70% of infant, 30% of under- five and 7% -11% of maternal mortality in Nigeria. The World Health organization recommended malarial drug prophylaxis for pregnant women in malaria endemic areas to prevent the adverse consequences of malaria in pregnancy....
13. EVALUATION OF THE DISSOLUTION AND OTHER CHARACTERISTICS OF CYCLODEXTRIN MOLECULAR INCLUSION COMPLEXES OF ARTEMETHER
ABSTRACT
The present study aimed to improve the dissolution rate, solubility and ultimately, bioavailability of poorly soluble artemether, an antimalarial drug, through inclusion complex formation with hydroxypropyl-β-cyclodextrin. The solid complexes of artemether and hydroxypropy...
14. IN VITROANTIMALARIAL SUSCEPTIBILITY OF PLASMODIUM FALCIPARUM ISOLATES FROM PATIENTS ATTENDING A HEALTH FACILITY IN NIGERIA
ABSTRACT
The continous emergence and spread of resistant strains of Plasmodium falciparumisolates to single and combined antimalarial drug has resulted to increase in mortality rate associated with the disease, especially in the African Continent as a whole and Nigeria in particular whe...
15. PHYTOCHEMICAL AND ANTIMALARIAL STUDIES OF THE LEAVES OF UVARIA CHAMAE P.BEAUV. (ANNONACEAE)
ABSTRACT
Uvaria chamae P.Beauv. belong to the Annonaceae family of flowering plants. It is distributed in the savannah and secondary forest. The plant is used in ethnomedicine for the treatment of malaria, inflammation, gonorrhea, dysentery; pile and fever. The ethyl alcohol leaves extr...
16. PHYTOCHEMICAL AND ANTICONVULSANT STUDIES ON METHANOL EXTRACT OF THE ROOTBARK OFUVARIA CHAMAEP. BEAUV. (ANNONACEAE)
ABSTRACT
Uvariachamae P. Beauv. (Annonaceae) is widely distributed inAfrica, the plant species are used in traditional medicine as an anti-inflamatory, antimalarial, and analgesic. It is also used for treatment of jaundice, epilepsy and microbial infections. The powdered rootbark of U.c...
17. ANTI-PLASMODIAL EFFECTS OF POLYALTHIA LONGIFOLIA (VAR.) LEAF EXTRACTS AGAINST PLASMODIUM BERGHEI IN MICE
ABSTRACT Malaria is one of the most debilitating tropical parasitic diseases and the greatest cause of hospitalization and death. Recurring problems of drug resistance are reinforcing the need for finding new antimalarial drugs. In this respect, natural plant products are the main sources of biol...
18. ANTI-PLASMODIAL, ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES OF ALKALOID FRACTION OF Maytenus senegalensis LEAF IN MICE
ABSTRACT
The treatment inadequacy and toxicity associated with conventional anti-malarial, antiinflammatory and analgesic drugs calls for the search for alternatives from medicinal plants, particularly. In the present study, alkaloid fraction of Maytenus senegalensis leaf was evaluated...
19. EVALUATION OF BIOACTIVE METABOLITE CONTENTS, MOSQUITO LARVICIDAL AND ANTI-PLASMODIAL ACTIVITIES OF EXTRACTS OF THE SPIDER Neoscona adianta
ABSTRACT
In spite of the extensive control efforts, over the years, mosquito still transmit serious human diseases, cause millions of deaths every year and the development of resistance to chemical insecticides resulting in rebounding vectorial capacity. This situation is aggravated wit...
20. EVALUATION OF HAEMATOLOGICAL PROFILES OF WOMEN AND CHILDREN INFECTED WITH MALARIAL PARASITES IN BOSSO AND PAIKORO LOCAL GOVERNMENT AREAS OF NIGER STATE
ABSTRACT
Malaria continues to be a major public health challenge especially in the African region despite the availability of anti malarial drugs and the application of several preventive strategies such as the use of insecticide treated nets, indoor residual spraying, and intermittent...
21. IN VIVO EFFICACY OF METHANOLIC EXTRACTS OF ROOT AND LEAF OF Morinda lucida IN Plasmodium berghei - INFECTED MICE
ABSTRACT
Therapeutic effects of the methanolic root extract and a combination of leaf and root extracts of Morinda lucida were evaluated for antiplasmodial activities. The phytochemical screening of the methanolic root extract showed the presence of saponins, flavonoids, alkaloids, phen...
22. ANTIPLASMODIAL ACTIVITY OF AQUEOUS AND ETHANOLIC EXTRACTS OF ANACARDIUM OCCIDENTALE AND CYMBOPOGON CITRATUS
ABSTRACT
The search for antimalarial compounds was necessitated by Plasmodium falciparum resistance to most antimalarial drugs. In endemic countries where malaria is prevalent, medicinal plants are often used to treat malaria. In this study, the in vitro antimalarial activities of crude...
23. Broadcasting as a Tool for Combating Malaria: A Study of Akko Local Government Area, Gombe State
Chapter One: Introduction
1.1 Background of the Study
Malaria remains one of the most prevalent and deadly diseases in sub-Saharan Africa, including Nigeria. Akko Local Government Area (LGA) in Gombe State is not exempt from this health challenge. Broadcasting, particularly th...
24. The Role of Development Communication in Reducing Malaria Prevalence in Wamakko Local Government Area, Sokoto State
Background of the Study
Malaria is a major public health challenge in Nigeria, with Wamakko Local Government Area, Sokoto State, being one of the high-burden areas. The prevalence of malaria in this region is influenced by factors such as inadequate access to healthcare...
25. The Effect of Public Health Policies on the Eradication of Malaria in Gombe Local Government, Gombe State
Background of the Study
Malaria is one of the most significant public health challenges in sub-Saharan Africa, with Nigeria being among the countries with the highest burden of the disease. In Gombe Local Government, Gombe State, malaria remains a leading cause of morbi...
26. An Assessment of Malaria Prevention Programs and Workforce Productivity in Wukari Local Government Area, Taraba State
Background of the Study
Malaria remains one of the leading causes of morbidity and mortality in sub-Saharan Africa, including Nigeria. In Wukari Local Government Area (LGA), Taraba State, malaria significantly affects the health of the workforce, reduci...
27. An Assessment of Nurses’ Role in Malaria Prevention and Treatment Among Children in Borno State
Background of the Study: Malaria remains one of the leading causes of morbidity and mortality in children under five years old in Nigeria, including in Borno State (Ajibola et al., 2023). The burden of malaria is exacerbated by inadequate access to healthcar...
28. The Effect of Nurses' Role in Malaria Prevention Awareness Among Rural Communities in Taraba State
Background of the Study:
Malaria remains a leading cause of morbidity and mortality in Sub-Saharan Africa, particularly in rural areas where access to healthcare services is limited. In Nigeria, Taraba State is one of the regions most affected by malaria, with a signifi...
29. An Evaluation of the Role of Community Health Nurses in Malaria Control in Yobe State
Background of the Study
Malaria remains a major public health challenge in Nigeria, particularly in regions such as Yobe State, where the prevalence of the disease is high due to favorable climatic conditions for mosquito breeding (World Malaria Report, 2024). Community health nurses (C...
30. The Impact of Nursing Interventions on the Management of Malaria in Pregnant Women in Gombe State
Background of the Study
Malaria in pregnancy is a significant public health concern in sub-Saharan Africa, including Nigeria, where the disease remains one of the leading causes of maternal and fetal morbidity and mortality. Pregnant women are particularly vulnerable to malaria due to p...
31. An Appraisal of the Role of Nurses in Managing Malaria in Children Under Five in Adamawa State
Background of the Study
Malaria remains a major public health concern in Nigeria, particularly among children under five, who are the most vulnerable to severe complications and mortality. According to the World Health Organization (WHO), Nigeria acco...
32. The Effect of Nursing Care on the Recovery of Children with Severe Malaria in Adamawa State
Background of the Study
Malaria remains a significant public health challenge, particularly in sub-Saharan Africa, where it is one of the leading causes of morbidity and mortality. The World Health Organization (WHO) reports that approximately 200 mil...
33. An Investigation of the Impact of Health Education on Childhood Malaria Prevention in Borno State
Background of the Study
Malaria remains one of the leading causes of morbidity and mortality among children under five in Nigeria, with Borno State being among the regions most affected (Mohammed et al., 2023). Despite the availability of preventive m...
34. A Correlational Study of Pediatric Health Education and the Incidence of Malaria in Kebbi State
Background of the Study
Malaria is one of the leading causes of morbidity and mortality among children under five years of age in Nigeria, particularly in the northern regions, including Kebbi State. The incidence of malaria in children...
35. An evaluation of nurses' knowledge and adherence to malaria treatment protocols at Federal Medical Centre, Yenagoa.
Background of the study
Malaria remains one of the leading causes of morbidity and mortality in sub-Saharan Africa, with the World Health Organization (WHO) estimating that the region accounts for over 90% of global malaria cases (WHO, 2023). In Nigeria, the disease con...
36. An Evaluation of Nurse-Led Malaria Prevention Programs for Pregnant Women in Nasarawa State
Background of the Study
Malaria remains one of the leading causes of maternal and neonatal morbidity in Nigeria, with pregnant women being particularly vulnerable due to their reduced immunity. The World Health Organization (WHO, 2024) recommends a co...
37. An assessment of the role of insecticide-treated nets in malaria prevention in Adamawa State
Background of the Study
Malaria remains a major public health challenge in Nigeria, accounting for a significant proportion of morbidity and mortality, particularly among children under five and pregnant women. According to the WHO (2024), Nigeria bears approximately 27% of the global m...
38. An Evaluation of the Effectiveness of Malaria Rapid Diagnostic Tests in Nasarawa State
Background of the Study
Malaria remains one of the leading causes of morbidity and mortality in Nigeria, accounting for approximately 60% of outpatient visits and 30% of hospital admissions (WHO, 2024). Prompt and accurate diagnosis is critical for effective treatment and malaria contro...
39. The Impact of Insecticide Resistance on Malaria Control Efforts in Kaduna State
Background of the Study
Malaria remains one of the most significant public health challenges in sub-Saharan Africa, including Nigeria, where the disease is endemic (Ogbu et al., 2024). Insecticide-treated nets (ITNs), indoor residual spraying (IRS), and other insecticide-based intervent...
40. The Impact of Malaria Control Interventions on Disease Prevalence in Sokoto State
Background of the Study
Malaria remains a significant public health concern, particularly in sub-Saharan Africa, where it contributes to high morbidity and mortality rates (World Health Organization [WHO], 2023). Nigeria, being one of the most affected countries, accounts for approximat...
41. An Appraisal of the Effectiveness of Community Health Workers in Malaria Control in Borno State
Background of the Study
Malaria remains a major public health challenge in sub-Saharan Africa, with Nigeria accounting for a significant proportion of global cases and deaths (World Health Organization [WHO], 2024). The disease, caused by Plasmodium parasites and transmitted t...
42. An Evaluation of Public Health Interventions and Their Statistical Impact on Malaria Reduction in Zamfara State
Background of the Study
Malaria remains a significant public health concern in Nigeria, accounting for a substantial proportion of global malaria morbidity and mortality (WHO, 2024). Nigeria contributes approximately 27% of the global malaria burden, with northern states such as Zamfara...
43. An appraisal of malaria treatment adherence among patients in Zamfara State
Background of the Study
Malaria remains one of the most significant public health challenges in sub-Saharan Africa, and Nigeria, including Zamfara State, bears a disproportionate burden of the disease. Malaria is primarily caused by Plasmodium parasites transmitted through the bites of...
44. An Investigation of Community Perceptions of Malaria Prevention Strategies in Kogi State
Background of the Study
Malaria remains one of the most pressing public health challenges in Nigeria, accounting for approximately 23% of global malaria cases and 19% of malaria-related deaths. The World Health Organization (WHO) has long emphasized t...
45. An Evaluation of Malaria Control Strategies and Their Effectiveness in Kano State
Background of the Study
Malaria remains a leading cause of morbidity and mortality in many parts of sub-Saharan Africa, including Kano State. The Nigerian government, alongside international organizations, has implemented various malaria control strategies, such as the distribution of i...
46. Development of a Web-Based Bioinformatics Tool for Studying Genetic Mutations in Malaria Parasites: A Case Study of Kano University of Science and Technology, Wudil, Kano State
Background of the Study
Malaria remains a major public health concern in many parts of the world, particularly in sub-Saharan Africa. The genetic mutations in malaria parasites significantly impact drug resistance and disease transmission dynamics. Consequently, understan...
47. Development of a Computational Biology Model for Drug Discovery in Malaria Treatment: A Case Study of University of Maiduguri, Borno State
Background of the Study
Malaria remains a major public health concern in Nigeria, and the development of new, effective drugs is essential for combating the disease. The University of Maiduguri in Borno State is at the forefront of research aimed at discovering novel drug...
48. Development of an AI-Based System for Predicting Malaria Drug Resistance: A Case Study of Abubakar Tafawa Balewa University, Bauchi State
Background of the Study
Malaria remains one of the most prevalent infectious diseases in Nigeria, with drug resistance being one of the key factors complicating treatment efforts. The emergence of drug-resistant malaria strains has made it increasingly difficult to manage...
49. An investigation into the factors influencing malaria drug resistance in Kano State
Background of the Study
Malaria remains a critical public health challenge in Nigeria, and Kano State is at the forefront of this burden. Over the past few decades, significant progress has been achieved through the widespread deployment of antimalarial drugs; however, the emergence of...
50. An Appraisal of the Implementation of the National Malaria Control Program in Kaduna State, Nigeria
Background of the Study
The National Malaria Control Program (NMCP) is a critical public health initiative aimed at reducing the burden of malaria through interventions such as insecticide-treated bed nets (ITNs), indoor residual spraying (IRS), and antima...
