1. ANALGESIC, ANTI-INFLAMMATORY AND OTHER PHARMACOLOGICAL ACTIVITIES OF METHANOL LEAF EXTRACT OF OLAX SUBSCORPIOIDEA OLIV (OLACACEAE) IN LABORATORY ANIMALS
ABSTRACT
Synthetic analgesic and anti-inflammatory drugs have major side effects such as constipation, nausea and vomiting, sedation and mental clouding, etc.,which have significantly limited their use.There is therefore, an intensification of search for newer analgesic and anti-inflamm...
2. ANTI-DIARRHOEAL AND SUBCHRONIC TOXICITY STUDIES ON METHANOL STEM BARK EXTRACT OF IRIVINGIA WOMBOLU VERMOESEN (IRVINGIACEAE) IN LABORATORY ANIMALS
Abstract
Irvingia wombolu is one of the herbal plants used as food for its nutritional values. It is also used as medicinal plant in the south-south and south-eastern part of Nigeria for the management of diarrhoea and other ailments. Although these medicinal plants are believed to be h...
3. ANTICONVULSANT AND SUB-CHRONIC TOXICITY STUDIES OF THE METHANOL LEAF EXTRACT OF DIOSPYROS MESPILIFORMIS HOCHST (EBENACEAE) IN LABORATORY ANIMALS
ABSTRACT
Diospyros mespiliformis hochst (Ebenaceae) known in English as ebony is a plant that is found throughout West Africa. The Plant was reported to have wide ethnomedical application notably in fever, whooping cough, wounds, pneumonia, syphilis, leprosy and epilepsy among others. T...
4. ANTICONVULSANT STUDIES ON METHANOL LEAF EXTRACT OF LAGGERAAURITA LINN.F.IN LABORATORY ANIMALS
ABSTRACT
LaggeraauritaLinn. belongs to the family of Asteraceae. It is an annual herb which is found growing as weeds in Nigeria and spread throughout the sub-Saharan Africa. In Nigeria, Laggeraaurita is used asa remedy for pediatric malaria and in the management of epilepsy in Niger st...
5. ANTIDIARRHOAEL EFFECT OF METHANOL STEM BARK EXTRACT OF HYMENOCARDIA ACIDA (EUPHOBIACEAE) IN LABORATORY ANIMALS
Abstract
The objective of the present study was to evaluate the antidiarrheal activity of the methanol stem bark extract of Hymenocardia acida in some laboratory animals. They methanol stem bark extract of Hymenocardia acida (MEHA) was prepared from the freshly collected stem bark of th...
6. COMPARATIVE EVALUATION OF THE HYPOTENSIVE EFFECTS OF THE SEED AND LEAF EXTRACTS OF MORINGA OLEIFERA LAM (Moringaceae) IN LABORATORY ANIMALS
ABSTRACT
Moringa oleifera is locally used in Nigeria for the management of respiratory disorders, hypertension and poor blood circulation among other ailments. However, all parts of the plant are blindly used because the exact part of this plant and / or extractive solvent that provides...
7. HYPOTENSIVE ACTIVITY AND TOXICOLOGICAL PROFILE OF STEM BARK EXTRACT OF SYZYGIUM GUINEENSE (Willd, D.C. Myrtaceae) IN LABORATORY ANIMALS
ABSTRACT
Hypertension of unknown cause is called essential or primary hypertension while hypertension of a known cause is called secondary hypertension. Hypertension is called a silent killer because it is usually asymptomatic. It is a global problem affecting 1 in 3 adults in the Unite...
8. SOME NEUROPHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE ETHANOLIC LEAF EXTRACT OF CUSSONIA BARTERI SEEMAN (ARALIACEAE) IN LABORATORY ANIMALS
ABSTRACT
Cussonia barteri is used in traditional medicinefor the management of convulsion and epilepsy, especially in children in Ghana and Nigeria. Literature survey revealed that the safety and efficacy of such important medicinal plant have not been scientifically validated. In the p...
9. EFFECTS OF DETOXIFICATION ON SOME PHARMACOLOGICAL PROPERTIES OF JATROPHA CURCAS LINN. (EUPHORBIACEAE) SEED OIL IN LABORATORY ANIMALS
Abstract
Jatropha curcas seed oil is a known energy source in biodiesel which but for its toxicity, also has potential of being used as food and in the pharmaceutical / cosmetic industries. This study was designed to detoxify solvent and mechanically extracted J. curcas oils and to asce...
10. GASTRO-INTESTINAL MUCOSAL PROTECTIVE PROPERTIES AND TOXICITY STUDIES ON THE METHANOL ROOT EXTRACT OF WALTHERIA INDICA LINN. (STERCULIACEAE) IN LABORATORY ANIMALS
ABSTRACT
Many countries worldwide including Nigeria use different parts of Waltheria indica (leaves, stem-barks, roots and whole plants) to treat various ailments. In Nigeria, Waltheria indica is used to treat gastro-intestinal ulcers, pain, inflammation, diarrhoea, conjunctivitis, anae...
11. SOME CARDIOVASCULAR ACTIVITIES OF THE AQUEOUS LEAF EXTRACT OF CROTON ZAMBESICUS LINN (EUPHORBIACEAE) IN LABORATORY ANIMALS
Abstract
Croton zambesicus Linn (Euphorbiaceae) is a highly valued medicinal plant in Nigeria and West African sub-region. It is used by traditional medicine practitioners in the treatment of various ailments including hypertension. This study aims to determine some cardiovascular activ...
12. SOME NEUROPHARMACOLOGICAL STUDIES ON ETHANOL EXTRACT AND FRACTIONS OF TAPINANTHUS GLOBIFERUS A. RICH MISTLETOE ON VITELLARIA PARADOXA HOST IN LABORATORY ANIMALS
ABSTRACT
Tapinanthus globiferus is a semi-parasite mistletoe which grows on branches of large number of trees including Vitellaria paradoxa. It used locally in the management of insomnia, epilepsy, anxiety, headaches and hypertension. This study evaluated the toxicity and neuropharmacol...
13. SOME UTEROTONIC PROPERTIES OF AQUEOUS LEAF EXTRACT OF SIDA CORYMBOSA (Fries) IN LABORATORY ANIMALS
ABSTRACT
Uterotonic property is the characteristic innate ability of a substance to spontaneously initiate and maintain uterine contractions due to its chemical composition. Over centuries, sub-saharan Africans have been using Sida corymbosa leaf extract during labour with the claims th...
14. SOME NEUROPHARMACOLOGICAL STUDIES OF EXTRACT AND FRACTIONS OF CRINUM ZEYLANICUM(L.) (AMARYLLIDACEAE)BULB IN LABORATORY ANIMALS
ABSTRACT
Crinum zeylanicum is a medicinal plant used in folk medicine for management of general debility, infantile seizures and pain. Some neuropharmacological effects of methanolic bulb extract of Crinum zeylanicum were studied in laboratory animals.The Phytochemical screening of the...
15. THE EFFECT OF METHANOL RHIZOME EXTRACT OF Nymphaea lotus LINN. (NYMPHAEACEAE) IN ANIMAL MODELS OF DIARRHOEA
Abstract
Nymphaea lotus is one of the foremost aquatic macrophytes that have been identified in Nigerian fresh water bodies. It finds applications in the management of circulatory system disorders, digestive system disorders, infectionsand inflammations. This study aims to evaluate the...
16. STUDIES ON YERSINIOSIS IN HUMAN AND SELECTED ANIMAL POPULATIONS IN JOS AND ITS ENVIRONS
ABSTRACT
Yersinia enterocolitica and Yersinia pseudotuberculosis are important food and water borne pathogens that has recently emerged world wide. This study was aimed at characterizing the prevalence of Yersinia enterocolitica and Yersinia pseudotuberculosis in human and selected anim...
