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1. HEALTH EDUCATION AS A PARAGIDM TO AN ENVIRONMENTAL HEALTH OFFICER

Background to the Study

According to Professor Emmanuel Ofeme, in Owerri, while delivering lecture at the 2nd Sam Okwaraji Memorial Lecture, Published by Chimaobi Uchendu, in the Sun News online sports of Friday, September 19, 2008, he said that unlike vision 2010, whic...

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2. PERCEPTION OF FEMALE STUDENTS TOWARDS SEX EDUCATION IN NIGERIA

ABSTRACT

This study focuses on the perception of female students towards sex Education in the University of Calabar, Calabar, Cross River State. The variable such as sex, sexual transmitted disease, contraceptives, indecent exposures, Abstinence was dis...

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3. DEVELOPMENT OF EUCALPYTUS TERETICORNIS COMPOSITE (BARKS AND LEAVES) ADSORBENT FOR ADSORPTION OF CHROMIUM (VI) AND LEAD (II) IONS FROM SIMULATED WASTEWATER

Abstract

The research titled Development of Eucalpytus tereticornis composite for chromium (VI) and lead (II) ions adsorption from simulated wastewater was aimed to establish the efficacy of Eucalpytus tereticornis composite as an adsorbent applied in the adsorption of Cr6+ and Pb2+ ion...

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4. COMPARISON OF THE EFFECTS OF CIMETIDINE AND DIAZEPAM ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN VOLUNTEERS

ABSTRACT

The influence of Cimetidine (400 mg) and Diazepam (5 mg) on the pharmacokinetics of oral paracetamol (1000 mg) was studied and compared in eight (8) healthy human under two (2) protocols; concomitant and delayed administration of paracetamol. Subjects received one treatment at...

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5. CHRONOMODULATED NIFEDIPINE ADMINISTRATION AND MICROVASCULAR COMPLICATIONS IN GLIMEPIRIDE-TREATED HYPERGLYCAEMIC RATS

ABSTRACT

Diabetic complications pose increasing public health problems worldwide. Glimepiride, a sulphonylurea is among the most frequently used anti-diabetic drugs, and is often combined with other drugs for the management of type 2 diabetes mellitus. Nifedipine, a calcium channel bloc...

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6. COMPARISON OF THE EFFECTS OF CIMETIDINE AND TRAMADOL ON THE DISPOSITION OF PARACETAMOL IN HEALTHY HUMAN VOLUNTEERS

ABSTRACT

The influence of cimetidine (400mg) and Tramadol (100mg) on the disposition of oral single dose (1g) Paracetamol was studied and compared in 8 healthy human volunteers under two protocols; concomitant and delayed paracetamol administration. Subjects received one treatment at ea...

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7. COMPARISON OF THE EFFECTS OF CIMETIDINE AND METHYLDOPA ON THE PHARMACOKINETICS OF PARACETAMOL IN HUMAN

ABSTRACT

Comparison of the effects of cimetidine and methyldopa were studied in 5 phases: via phase I, ingestion of paracetamol 1g alone, phase II, administration of paracetamol 1g and cimetidine 400mg concurrently, phase III administration of cimetidine 400mg followed by paracetamol 1g...

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8. COMPARISON OF THE EFFECT OF A SINGLE ORAL DOSE OF CIMETIDINE AND PROPANTHELINE ON THE PHARMACOKINETIC OF PARACETAMOL IN HUMAN

ABSTRACT

Comparison of the effects of a single oral dose of cimetidine and propantheline on the pharmacokinetics of paracetamol were studied with paracetamol (1g) administered alone, concurrently with cimetidine (400mg), delay (1 hour) with cimetidine (400mg), concurrently with paraceta...

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9. FORMULATION STUDIES OF TABLETS CONTAINING ADANSONIA DIGITATA L. MUCILAGE AS MATRIX FORMER

ABSTRACT

The aim of this study was to investigate the ability of Adansonia digitata mucilage (ADM), a hydrophilic plant polymeric material to prolong the release of Metoprolol tartarate (MPT) from matrix tablet formulations compared with semi -synthetic polymer-HPMC60SH4000 matrices. Ph...

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10. EFFECT OF CAFFEINE ON PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN VOLUNTEERS: A CASE STUDY OF PANADOL EXTRA®

ABSTRACT

Acetaminophen or paracetamol is an analgesic and anti-pyretic agent widely used for treatment of headaches, minor pains and in combination with other medications like cold remedies and opoid analgesics. Individuals with headaches and minor pains tend to use paracetamol with caf...

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11. EVALUATION OF CHRYSOPHYLLUM ALBIDUM (G. DON) FRUIT GUM AS A SUSTAINED RELEASE MATRIX IN TABLET FORMULATIONS

ABSTRACT

The goal of designing sustained release or controlled release delivery system is to reduce the frequency of dosing or to increase effectiveness of the drug by localization at the site of action, reducing the dose required or providing uniform drug delivery. Natural gums and pol...

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12. EFFECT OF RANITIDINE ON PHARMACOKINETIC PARAMETERS OF METRONIDAZOLE IN HEALTHY HUMAN VOLUNTEERS

ABSTRACT

Pharmacokinetics is the study of the time course of drug movement in the body during absorption, distribution, metabolism and elimination.Drug interactions are pharmacodynamic, pharmacokinetic, or clinical responses to the administration of a drugcombination that differs from t...

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13. EFFECTS OF ENVIRONMENTAL EXPOSURE ON THE PHARMACOKINETICS OF CIPROFLOXACIN TABLET IN HEALTHY HUMAN VOLUNTEERS

ABSTRACT

Ciprofloxacin is a flouroquinololone antibiotic that is commonly prescribed empirically in Nigeria due to its broad spectrum of activity. However, the drug product is illegally handled by drug hawkers that allow the drug to be exposed to some environmental forces which may affe...

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14. THE EFFECT OF VITAMIN C ON PHARMACOKINETIC PARAMETERS OF CHLOROQUINE IN HEALTHY HUMAN VOLUNTEERS

ABSTRACT

This study was undertaken to compare the effect of vitamin C on the pharmacokinetics of chloroquine using human volunteers. Quality control studies for both chloroquine and vitamin C; identification test, assay, weight variation, friability, disintegration time and dissolution...

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15. EFFECTS OF CHLORPHENIRAMINE ON THE PHARMACOKINETICS OF ASCORBIC ACID IN HEALTHY MALE VOLUNTEERS

ABSTRACT

Ascorbic acid is a vitamin commonly used in the treatment of common cold and scurvy. It interacts with some drugs during absorption from the gastrointestinal tract, in the systemic circulation or during metabolism in the liver. However, interaction between ascorbic acid and chl...

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16. THE EFFECTS OF CHLOROQUINE, PARACETAMOL AND PROMETHAZINE ON THE PHARMACOKINETICS OF CHLORPROPAMIDE IN HUMAN VOLUNTEERS

ABSTRACT

The effect of chloroquine, paracetamol and Promethazine on the pharmacokinetic profile of chlorpropamide was investigated in human subjects. The batches of chlorpropamide, chloroquine, paracetamol and Promethazine used were subjected to quality control studies using official me...

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17. OPTIMIZATION STUDIES OF PROCESS PARAMETERS FOR THE ADSORPTION OF COPPER AND ARSENIC IONS FROM SIMULATED WASTE WATER USING CHITOSAN AND CHITOSAN – ZEOLITE BEADS

ABSTRACT

This research presents the “Optimization Studies of Process Parameters for the Adsorption of Copper and Arsenic Ions from Simulated Waste Water using Chitosan and Chitosan – Zeolite Beads” which was achieved by developing adsorbents of chitosan and chitosan &n...

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18. COMBINED EXPERIMENTAL AND MODELING STUDIES REVEAL NEW MECHANISMS IN T CELL ANTIGEN RECOGNITION

SUMMARY

T cells of the immune system recognize small antigen peptide fragments loaded onto Major Histocompatibility Complex (MHC) molecules through their T Cell Receptor (TCR). The recognition of antigenic pMHC by the TCR is an extremely sensitive and specific process, discriminating as...

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19. DEVELOPMENT OF CARBON OXIDES SEQUESTRATION FROM YAMAHA EF1000 GENERATOR USING POST-COMBUSTION CAPTURE TECHNIQUE

ABSTRACT

This work aimed atdevelopment of carbon oxides sequestration from Yamaha EF1000 generator using post - combustion capture technique. The state of the art is the use of monoethanolamine as sorbent for carbon sequestration. The present study postulated reaction mechanism of sawdu...

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20. KINETICS AND ENGINE PERFORMANCE OF BIODIESEL PRODUCED FROM SELECTED NON EDIBLESEEDSOILS USING ACTIVATED CLAY CATALYSTS

ABSTRACT

The kinetics and engine performance of biodiesel from African pear seed oil (APO) and Gmelina seed oil (GSO) by modified clay catalysts were carried out. The catalyst was synthesized by activating it with heat, phosphoric acid and sodium hydroxide. They were characterized using...

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21. KINETICS AND OPTIMIZATION OF CHALCOPYRITE, SPHALERITE AND ILMENITE LEACHING IN BINARY SOLUTIONS

ABSTRACT

Mineral ores are usually processed by means of pyrometallurgical or hydrometallurgical processes. Myriad of deficiencies surrounding pyrometallurgical process have spurred research interests geared toward low temperature and lixiviant concentration hydrometallurgical process. L...

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22. KINETICS AND OPTIMIZATION OF PHENOL UPTAKE FROM AQUEOUS SOLUTION USING AGRICULTURAL WASTES

ABSTRACT The uptake of phenol from simulated aqueous solution using agricultural wastes as adsorbents is the focus of this research work. The agricultural wastes used were corn cob and rice husk which were modified with tetraoxophosphate V acid (H3PO4) and carbonized to give corn cob activated ca...

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23. KINETICS AND RHEOLOGICAL BEHAVIOUR OF WASHABLE PAINTS FROM PALM KERNEL AND JATROPHA SEED OILS

Statement of the Problem

Toxic paints still dominate the local market, and as such, these paints are mostly used because they are cheap and readily avaliable. The few available non-toxic paints (washable paint) are sold at high price because the major raw materials are not locally sourc...

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24. OPTIMIZATION, ENGINE PERFORMANCE AND KINETICS STUDIES OF BASE METHANOLYSIS OF SELECTED SEED OILS FOR BIODIESEL PRODUCTION

Statement of the Problem

Globally, the Renewable Energy Network for 21st century (REN21) and other national strategies like the Nigerian Renewable Energy Master Plan (REMP), National Renewable Energy and Energy Efficiency Policy (NREEEP), Renewable Electricity Policy Guidelines (REPG) e...

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25. THE KINETIC STUDY ON HYDROLYSIS OF CELLULOSE (SAW-DUST)

ABSTRACT

This research project studied on the kinetics of hydrolysis of cellulose to glucose. The steps employed to achieve this project involved extraction of cellulose from sawdust and subsequently, hydrolysis of starch to simple sugar. This was followed by glucose analysis. Different...

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26. ACETYLATION OF CORN COB AND MANGO KERNEL- KINETICS AND APPLICATION FOR NON-AQUEOUS ADSORPTION PROCESSES

Justification for the Research

Residents of wetlands like the Nigeria’s Niger delta are concerned about the environmental impact of residual oil spill into receiving surface waters and land. The adverse effect of oil spill to the ecosystem and the long term effect of environmental...

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27. ACETYLATION OF SELECTED AGRICULTURAL WASTES- KINETICS AND APPLICATION FOR OIL SPILL CLEAN UP

STATEMENT OF PROBLEM

When oil is spilt into the environment, it causes different kinds of pollution that have serious adverse effects on man, animals and plants. These adverse impacts to the ecosystems and the long term environmental pollution calls for urgent need to develop a wide ran...

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28. EVALUATION OF THE BIOFUEL PROPERTIES OF THE METHYL, ETHYL ESTERS AND ESTER/DIESEL BLENDS OF THREE SEEDS OILS.

ABSTRACT

The depletion and price fluctuations of fossil fuel in the international market have been a major source of concern in total dependence on diesel fuel hence use of biodiesel produced from vegetable oil is a good substitute or additive fuel. Studies were carried out to investiga...

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29. OPTIMIZATION AND KINETICS OF COAGULATION-FLOCCULATION PROCESS FOR THE TREATMENT OF PAINT INDUSTRY EFFLUENT USING NATURAL COAGULANTS

Statement of the problem

Paint industry is one of the fastest growing economies in Nigeria. The effluents its discharge has contributed a lot to the pollution of our environment because of toxic chemicals and heavy metals that are emanating from them (Körbahti and Tanyolac¸ 2...

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30. AFFINITY AND REACTIVITY STUDIES OF THE REACTION OF HUMAN (Homo sapiens) AND CAT (Felis catus) HAEMOGLOBINS WITH 5,5´-DITHIOBIS(2-NITROBENZOATE)

ABSTRACT

Some haemoglobins have high oxygen affinity (high-affinity) while others have low oxygen affinity (low-affinity) as exemplified in human and cat haemoglobins respectively. High-affinity haemoglobins bind organic phosphates strongly and this lowers their oxygen affinities and th...

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