1. HEALTH EDUCATION AS A PARAGIDM TO AN ENVIRONMENTAL HEALTH OFFICER
Background to the Study
According to Professor Emmanuel Ofeme, in Owerri, while delivering lecture at the 2nd Sam Okwaraji Memorial Lecture, Published by Chimaobi Uchendu, in the Sun News online sports of Friday, September 19, 2008, he said that unlike vision 2010, whic...
2. PERCEPTION OF FEMALE STUDENTS TOWARDS SEX EDUCATION IN NIGERIA
ABSTRACT
This study focuses on the perception of female students towards sex Education in the University of Calabar, Calabar, Cross River State. The variable such as sex, sexual transmitted disease, contraceptives, indecent exposures, Abstinence was dis...
3. ASSESSMENT OF SAWDUST ACTIVATED CARBON (SAC) IN THE TREATMENT OF AQUACULTURE EFFLUENT
ABSTRACT
This study is aimed at the assessment of sawdust activated carbon in the treatment of aquaculture effluent with various objectives which includes the determination of the SAC properties, effluent parameters, effect of operating conditions and application of relevant adsorption...
4. DEVELOPMENT OF EUCALPYTUS TERETICORNIS COMPOSITE (BARKS AND LEAVES) ADSORBENT FOR ADSORPTION OF CHROMIUM (VI) AND LEAD (II) IONS FROM SIMULATED WASTEWATER
Abstract
The research titled Development of Eucalpytus tereticornis composite for chromium (VI) and lead (II) ions adsorption from simulated wastewater was aimed to establish the efficacy of Eucalpytus tereticornis composite as an adsorbent applied in the adsorption of Cr6+ and Pb2+ ion...
5. COMPARISON OF THE EFFECTS OF CIMETIDINE AND DIAZEPAM ON THE PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN VOLUNTEERS
ABSTRACT
The influence of Cimetidine (400 mg) and Diazepam (5 mg) on the pharmacokinetics of oral paracetamol (1000 mg) was studied and compared in eight (8) healthy human under two (2) protocols; concomitant and delayed administration of paracetamol. Subjects received one treatment at...
6. CHRONOMODULATED NIFEDIPINE ADMINISTRATION AND MICROVASCULAR COMPLICATIONS IN GLIMEPIRIDE-TREATED HYPERGLYCAEMIC RATS
ABSTRACT
Diabetic complications pose increasing public health problems worldwide. Glimepiride, a sulphonylurea is among the most frequently used anti-diabetic drugs, and is often combined with other drugs for the management of type 2 diabetes mellitus. Nifedipine, a calcium channel bloc...
7. COMPARISON OF THE EFFECTS OF CIMETIDINE AND TRAMADOL ON THE DISPOSITION OF PARACETAMOL IN HEALTHY HUMAN VOLUNTEERS
ABSTRACT
The influence of cimetidine (400mg) and Tramadol (100mg) on the disposition of oral single dose (1g) Paracetamol was studied and compared in 8 healthy human volunteers under two protocols; concomitant and delayed paracetamol administration. Subjects received one treatment at ea...
8. COMPARATIVE BIOEQUIVALENCE STUDIES OF SOME SELECTED BRANDS OF CIPROFLOXACIN TABLETS MARKETED IN NIGERIA
ABSTRACT
Comparative bioequivalence studies of six selected brands of ciprofloxacin tablets was successfully conducted. In-vitro quality control studies were carried out on six randomly selected brands of ciprofloxacin to establish identity, weight uniformity, friability, crushing stren...
9. COMPARISON OF THE EFFECTS OF CIMETIDINE AND METHYLDOPA ON THE PHARMACOKINETICS OF PARACETAMOL IN HUMAN
ABSTRACT
Comparison of the effects of cimetidine and methyldopa were studied in 5 phases: via phase I, ingestion of paracetamol 1g alone, phase II, administration of paracetamol 1g and cimetidine 400mg concurrently, phase III administration of cimetidine 400mg followed by paracetamol 1g...
10. COMPARATIVE BIOAVAILABILITY STUDIES OF PARACETAMOL BRANDS IN HUMANS
ABSTRACT
The comparative bioavailabilities (bioequivalence) of five generic brands of paracetamol were compared in six (6) healthy male volunteers. The aim was to study whether the generic brands are bioequivalent to the standard brand. The study was carried out following oral administr...
11. COMPARISON OF THE EFFECT OF A SINGLE ORAL DOSE OF CIMETIDINE AND PROPANTHELINE ON THE PHARMACOKINETIC OF PARACETAMOL IN HUMAN
ABSTRACT
Comparison of the effects of a single oral dose of cimetidine and propantheline on the pharmacokinetics of paracetamol were studied with paracetamol (1g) administered alone, concurrently with cimetidine (400mg), delay (1 hour) with cimetidine (400mg), concurrently with paraceta...
12. FORMULATION STUDIES OF TABLETS CONTAINING ADANSONIA DIGITATA L. MUCILAGE AS MATRIX FORMER
ABSTRACT
The aim of this study was to investigate the ability of Adansonia digitata mucilage (ADM), a hydrophilic plant polymeric material to prolong the release of Metoprolol tartarate (MPT) from matrix tablet formulations compared with semi -synthetic polymer-HPMC60SH4000 matrices. Ph...
13. EFFECT OF CAFFEINE ON PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN VOLUNTEERS: A CASE STUDY OF PANADOL EXTRA®
ABSTRACT
Acetaminophen or paracetamol is an analgesic and anti-pyretic agent widely used for treatment of headaches, minor pains and in combination with other medications like cold remedies and opoid analgesics. Individuals with headaches and minor pains tend to use paracetamol with caf...
14. EVALUATION OF CHRYSOPHYLLUM ALBIDUM (G. DON) FRUIT GUM AS A SUSTAINED RELEASE MATRIX IN TABLET FORMULATIONS
ABSTRACT
The goal of designing sustained release or controlled release delivery system is to reduce the frequency of dosing or to increase effectiveness of the drug by localization at the site of action, reducing the dose required or providing uniform drug delivery. Natural gums and pol...
15. EFFECT OF GREEN TEA (CAMELLIA SINENSIS) ON THE PHARMACOKINETIC PROFILE OF CEPHALEXIN IN HEALTHY HUMAN VOLUNTEERS
ABSTRACT
Tea is a herb commonly consumed globally. Herbs are often taken concurrently with conventional medicines which results in increased potential of drug-herb interactions, and this may have important clinical significance based on an increasing number of reports of such interactio...
16. EFFECT OF RANITIDINE ON PHARMACOKINETIC PARAMETERS OF METRONIDAZOLE IN HEALTHY HUMAN VOLUNTEERS
ABSTRACT
Pharmacokinetics is the study of the time course of drug movement in the body during absorption, distribution, metabolism and elimination.Drug interactions are pharmacodynamic, pharmacokinetic, or clinical responses to the administration of a drugcombination that differs from t...
17. EFFECTS OF ENVIRONMENTAL EXPOSURE ON THE PHARMACOKINETICS OF CIPROFLOXACIN TABLET IN HEALTHY HUMAN VOLUNTEERS
ABSTRACT
Ciprofloxacin is a flouroquinololone antibiotic that is commonly prescribed empirically in Nigeria due to its broad spectrum of activity. However, the drug product is illegally handled by drug hawkers that allow the drug to be exposed to some environmental forces which may affe...
18. THE EFFECT OF VITAMIN C ON PHARMACOKINETIC PARAMETERS OF CHLOROQUINE IN HEALTHY HUMAN VOLUNTEERS
ABSTRACT
This study was undertaken to compare the effect of vitamin C on the pharmacokinetics of chloroquine using human volunteers. Quality control studies for both chloroquine and vitamin C; identification test, assay, weight variation, friability, disintegration time and dissolution...
19. EFFECTS OF CHLORPHENIRAMINE ON THE PHARMACOKINETICS OF ASCORBIC ACID IN HEALTHY MALE VOLUNTEERS
ABSTRACT
Ascorbic acid is a vitamin commonly used in the treatment of common cold and scurvy. It interacts with some drugs during absorption from the gastrointestinal tract, in the systemic circulation or during metabolism in the liver. However, interaction between ascorbic acid and chl...
20. THE EFFECTS OF CHLOROQUINE, PARACETAMOL AND PROMETHAZINE ON THE PHARMACOKINETICS OF CHLORPROPAMIDE IN HUMAN VOLUNTEERS
ABSTRACT
The effect of chloroquine, paracetamol and Promethazine on the pharmacokinetic profile of chlorpropamide was investigated in human subjects. The batches of chlorpropamide, chloroquine, paracetamol and Promethazine used were subjected to quality control studies using official me...
21. EFFECTIVE WAYS OF CONTROLLING EROSION IN A BUILDING SITE IN SELECTED SITES IN EKWULOBIA ANAMBRA STATE
BACKGROUND OF THE STUDY
The development of soil erosion began when man settled down and started turning pasture land into farmland. The intensive exploitation of the land disturbed the natural soil vegetative cover and exposed its, surface to the effect of erosive...
22. ADSORPTION OF CHROMIUM(VI) AND COPPER(II) IONS FROM WELL WATER IN CHALLAWA INDUSTRIAL AREA USING PECTIN-CHITOSAN POLYELECTROLYTE COMPLEX
ABSTRACT
The aim of the research was to carryout adsorption study of the removal of chromium(vi) and copper(ii) ions from well water using pectin-chitosan polyelectrolyte complex as adsorbent. The optimum pH and ratio of pectin/chitosan was determined and the chitosan/pectin complex was...
23. OPTIMIZATION STUDIES OF PROCESS PARAMETERS FOR THE ADSORPTION OF COPPER AND ARSENIC IONS FROM SIMULATED WASTE WATER USING CHITOSAN AND CHITOSAN – ZEOLITE BEADS
ABSTRACT
This research presents the “Optimization Studies of Process Parameters for the Adsorption of Copper and Arsenic Ions from Simulated Waste Water using Chitosan and Chitosan – Zeolite Beads” which was achieved by developing adsorbents of chitosan and chitosan &n...
24. COMBINED EXPERIMENTAL AND MODELING STUDIES REVEAL NEW MECHANISMS IN T CELL ANTIGEN RECOGNITION
SUMMARY
T cells of the immune system recognize small antigen peptide fragments loaded onto Major Histocompatibility Complex (MHC) molecules through their T Cell Receptor (TCR). The recognition of antigenic pMHC by the TCR is an extremely sensitive and specific process, discriminating as...
25. PREPARATION AND CHARACTERISATION OF PLANTAIN WASTE BASED CELLULOSIC NANOCOMPOSITES FOR THE REMOVAL OF SELECTED HEAVY METALS FROM BATTERY EFFLUENT
ABSTRACT
In this study, Ag NPs and Ag-CNCs impregnated on CNTs nano adsorbents were developed using a combination of green chemistry protocol and chemical vapor deposition techniques and subsequently characterized using, HRTEM, HRSEM, XRD, EDS and SAED. The adsorption capability of silv...
26. SOLAR PHOTOCATALYTIC DEGRADATION OF ORGANIC POLLUTANTS IN LOCAL DYEING WASTEWATER USING NEEMMODIFIED GRAPHITIC CARBON NITRIDE (g-C3N4)
ABSTRACT
The discharge of dyeing wastewater containing high concentration of contaminants from the local dyeing industry has caused a serious environmental concern. The present study reports the synthesis of graphitic carbon nitride and itsutilization in degradation of dyeing effluent p...
27. KINETIC STUDIES OF SELECTED CORROSION INHIBITORS OF ALUMINIUM AND MILD STEEL IN ACID MEDIUM
Abstract
The corrosion inhibition of aluminium and mild steel in H2SO4 in the presence of Bromothymol blue, BTB, Dimethyl yellow, DMY, Methyl orange, MO, Titanium (IV) oxide, TO and Cassia Siamea Lam, CSL leaves extract at 303 – 313K was studied using “Absorbance difference&...
28. TORREFACTION AND CHARACTERIZATION OF MAHOGANY SAWDUST FOR SOLID FUEL PRODUTION
ABSTRACT
As interest in biomass utilization into combustion fuels grows, the torrefaction, becomes ever more important. Torrefaction is aimed to maximize energy by removing undesirable components (water, hemicellulose and volatile matter) which cause poor ignition characteristic, excess...
29. DEVELOPMENT OF CARBON OXIDES SEQUESTRATION FROM YAMAHA EF1000 GENERATOR USING POST-COMBUSTION CAPTURE TECHNIQUE
ABSTRACT
This work aimed atdevelopment of carbon oxides sequestration from Yamaha EF1000 generator using post - combustion capture technique. The state of the art is the use of monoethanolamine as sorbent for carbon sequestration. The present study postulated reaction mechanism of sawdu...
30. KINETIC MODELLING AND OPTIMIZATION OF THE DRYING OF COCOYAM AND POTATO
Statement of the problem
One of the major reasons for food shortage is the unavailability of adequate preservation facilities. Some of the food crops are seasonal, being readily available during some periods of the year and scare during other periods due to inefficient preservation. Pot...
31. KINETICS AND ENGINE PERFORMANCE OF BIODIESEL PRODUCED FROM SELECTED NON EDIBLESEEDSOILS USING ACTIVATED CLAY CATALYSTS
ABSTRACT
The kinetics and engine performance of biodiesel from African pear seed oil (APO) and Gmelina seed oil (GSO) by modified clay catalysts were carried out. The catalyst was synthesized by activating it with heat, phosphoric acid and sodium hydroxide. They were characterized using...
32. KINETICS AND OPTIMIZATION OF CHALCOPYRITE, SPHALERITE AND ILMENITE LEACHING IN BINARY SOLUTIONS
ABSTRACT
Mineral ores are usually processed by means of pyrometallurgical or hydrometallurgical processes. Myriad of deficiencies surrounding pyrometallurgical process have spurred research interests geared toward low temperature and lixiviant concentration hydrometallurgical process. L...
33. KINETICS AND OPTIMIZATION OF PHENOL UPTAKE FROM AQUEOUS SOLUTION USING AGRICULTURAL WASTES
ABSTRACT The uptake of phenol from simulated aqueous solution using agricultural wastes as adsorbents is the focus of this research work. The agricultural wastes used were corn cob and rice husk which were modified with tetraoxophosphate V acid (H3PO4) and carbonized to give corn cob activated ca...
34. KINETICS AND RHEOLOGICAL BEHAVIOUR OF WASHABLE PAINTS FROM PALM KERNEL AND JATROPHA SEED OILS
Statement of the Problem
Toxic paints still dominate the local market, and as such, these paints are mostly used because they are cheap and readily avaliable. The few available non-toxic paints (washable paint) are sold at high price because the major raw materials are not locally sourc...
35. OPTIMIZATION, ENGINE PERFORMANCE AND KINETICS STUDIES OF BASE METHANOLYSIS OF SELECTED SEED OILS FOR BIODIESEL PRODUCTION
Statement of the Problem
Globally, the Renewable Energy Network for 21st century (REN21) and other national strategies like the Nigerian Renewable Energy Master Plan (REMP), National Renewable Energy and Energy Efficiency Policy (NREEEP), Renewable Electricity Policy Guidelines (REPG) e...
36. REMOVAL OF TURBIDITY FROM PAINT AND BREWERY INDUSTRIAL WASTEWATERS USING SEQUENTIAL COAG-FLOCCULATION AND ADSORPTION PROCESSES
ABSTRACT
The continuous industrial development in Nigeria has resulted in the generation of industrial wastewaters. Thwastewaters are usually discharged without proper treatment which affects the environment. There are severatechniques applied in the treatment of wastewaters but c...
37. THE KINETIC STUDY ON HYDROLYSIS OF CELLULOSE (SAW-DUST)
ABSTRACT
This research project studied on the kinetics of hydrolysis of cellulose to glucose. The steps employed to achieve this project involved extraction of cellulose from sawdust and subsequently, hydrolysis of starch to simple sugar. This was followed by glucose analysis. Different...
38. ACETYLATION OF CORN COB AND MANGO KERNEL- KINETICS AND APPLICATION FOR NON-AQUEOUS ADSORPTION PROCESSES
Justification for the Research
Residents of wetlands like the Nigeria’s Niger delta are concerned about the environmental impact of residual oil spill into receiving surface waters and land. The adverse effect of oil spill to the ecosystem and the long term effect of environmental...
39. ACETYLATION OF SELECTED AGRICULTURAL WASTES- KINETICS AND APPLICATION FOR OIL SPILL CLEAN UP
STATEMENT OF PROBLEM
When oil is spilt into the environment, it causes different kinds of pollution that have serious adverse effects on man, animals and plants. These adverse impacts to the ecosystems and the long term environmental pollution calls for urgent need to develop a wide ran...
40. EVALUATION OF THE BIOFUEL PROPERTIES OF THE METHYL, ETHYL ESTERS AND ESTER/DIESEL BLENDS OF THREE SEEDS OILS.
ABSTRACT
The depletion and price fluctuations of fossil fuel in the international market have been a major source of concern in total dependence on diesel fuel hence use of biodiesel produced from vegetable oil is a good substitute or additive fuel. Studies were carried out to investiga...
41. OPTIMIZATION AND KINETICS OF COAGULATION-FLOCCULATION PROCESS FOR THE TREATMENT OF PAINT INDUSTRY EFFLUENT USING NATURAL COAGULANTS
Statement of the problem
Paint industry is one of the fastest growing economies in Nigeria. The effluents its discharge has contributed a lot to the pollution of our environment because of toxic chemicals and heavy metals that are emanating from them (Körbahti and Tanyolac¸ 2...
42. AFFINITY AND REACTIVITY STUDIES OF THE REACTION OF HUMAN (Homo sapiens) AND CAT (Felis catus) HAEMOGLOBINS WITH 5,5´-DITHIOBIS(2-NITROBENZOATE)
ABSTRACT
Some haemoglobins have high oxygen affinity (high-affinity) while others have low oxygen affinity (low-affinity) as exemplified in human and cat haemoglobins respectively. High-affinity haemoglobins bind organic phosphates strongly and this lowers their oxygen affinities and th...
43. CHARACTERISTICS OF SOME HYDROLYTIC ENZYMES AND BIOPULPING POTENTIAL OF FUNGAL ISOLATES FROM SELECTED WOOD SAMPLES IN SOUTHWESTERN NIGERIA
Abstract
Pulping industry is both labour and energy intensive but in Nigeria, electricity supply is unstable. This has contributed to the near collapse of the Nigerian paper and pulp industry despite the rich forest resources in southwestern Nigeria. Use of alternative energy sources su...
