BACKGORUND TO THE STUDY
It is well known that in order for a plant to protect itself, it creates certain compounds that can also protect humans from sickness. Today, there are approximately 4000 distinct phytochemicals that have the potential to alter disorders such as...
BACKGROUNG OF STUDY
Infectious diseases are a significant cause of morbidity and mortality worldwide, accounting for approximately 50% of all deaths in tropical countries and as much as 20% of deaths in the Americas. Despite the significant progress made in microb...
Background of the study
According to study conducted by Cancer Research UK in 2021, cancer is the primary cause of death in countries all over the globe. The World Health Organization (WHO) ranks colorectal cancer (CRC) as the fourth leading caus...
INTRODUCTION
Bread is a staple food prepared from a dough of flour and water usually by baking. It is a good source of good nutrient such as macronutrients (carbohydrates protein, and fats) and micronutrients (minerals and vitamins) that are essential for human health.<...
ABSTRACT
The plant Laggera aurita is an annual or biennial herb of widespread in dry waste places from across Senegal to Southern Nigeria. The plant has been reportedly used for medicinal purposes including treatment of rheumatic pain, healing of cuts and bruises, and as a last resort t...
ABSTRACT
The plant Andropogon gayanus is employed in herbal medicine for the treatment of various disease conditions. The dried root of the plant is soaked in milk and taken for the treatment of postpartum pain and bronchitis in North-west Nigeria. In this study the methanol root extrac...
ABSTRACT
Synthetic analgesic and anti-inflammatory drugs have major side effects such as constipation, nausea and vomiting, sedation and mental clouding, etc.,which have significantly limited their use.There is therefore, an intensification of search for newer analgesic and anti-inflamm...
ABSTRACT
The herbalists in several African Countries have used Rothmannia longiflora decoctions as febrifugal and analgesic agent. The present study examined the analgesic, anti-inflammatory and toxicological profile of the methanolic extract of the plant in experimental animals. The pr...
ABSTRACT
Honeybee Propolis from Apis mellifera (Linn), has been used in ethno medicine as an emollient in the treatment of ringworm, measles, chickenpox and with reported biological activities, such as antitumor, antioxidant, immunomodulatory action and anti-inflammatory action among ot...
ABSTRACT
The leaf of Mitracarpusvillosus (Sw.) DC. (Rubiaceae) is used in West African folk medicine for the management of a plethora of stress-related diseases including headaches and toothaches. In this study, preliminary phytochemical analysis of the ethylacetateleaf extract of Mitra...
ABSTRACT
Acacia niloticais a multipurpose plant belonging to the family Mimosaceae. Commonly known as Prickly acacia in English and Bagaruwa in Hausa, It has medicinal properties which include antimalaria, antimicrobial, anti-inflammatory, anticancer, etc. Traditionally, the pods are us...
ABSTRACT
Vernonia amygdalina Del. and V. kotschyana Sch. Bip. (Asteraceae) are respectively shrub or tree and annual herb found commonly in tropical and subtropical countries. They are employed in ethno-medicine in the treatment of many ailments namely stomach ache, gingivitis, rheumati...
ABSTRACT
Microtrichia perotitii DC Asteraceae (Compositeae) is an herb found in the tropical countries. Ethno-medicinally, it is mainly used for the treatment of pain related diseases such as toothaches, cuts and burns and few ailments like rashes, rheumatism, jaundice, stomachaches and...
Abstract
Indigofera hirsuta Linn. (Leguminosae) is a well-known plant used in African traditional medicine as an anti-inflammatory, antibacterial, antiulcer, anti-venom and anticonvulsant. The air-dried aerial parts of I. hirsuta was extracted with methanol using a soxhlet extractor and...
Abstract
The ethanol extract of root of Chrozophora senegalensis use in ethanomedicine to treat diarrhea, rheumatism, taeniasis, stomach ache, inflammation and veneral diseases was subjected to Phytochemical and Biological studies. Phytochemical analysis was carried out using standard p...
ABSTRACT
The plant Ampelocissus grantii is used in traditional medicinal practice in the treatment of cough, wounds, venereal infections and other ailments.Phytochemical examination of the methanol extract of the aerial parts of Ampelocissus grantii (Baker) Planch (Family, Vitaceae) rev...
ABSTRACT
Chronic inflammation has been implicated in most non-communicable/chronic degenerative diseases including age-related cancers. Ziziphus mucronata, a plant used in ethnomedicine to treat different painful and inflammatory conditions, was subjected to phytochemical investigation...
ABSTRACT
The aim of this study was to enhance the solubility and hence dissolution rate of two poorly soluble drugs: ibuprofen and piroxicam using Eudragit RS 100 and hydroxymethylpropylcellulose (HPMC) as carriers, by solid dispersion technique and to evaluate the effect of trona (sodi...
ABSTRACT
Some pharmacological effects of the 70% ethanolic stem bark extract of Pterocarpus erinaceus were investigated in experimental animals. Preliminary Phytochemical studies of the ethanolic extract revealed the presence of Tannins, Carbohydrates, Proteins & Amino acids, Flavon...
ABSTRACT
Securinega virosa is one of the African medicinal plants described as a true “cure all” among traditional practitioners. Different parts of Securinega virosa have been used in the management of different disorders in Nigeria and other parts of the world. There is th...
ABSTRACT
The decoction of the leaves of Dalbegia saxatilis is used in Traditional Medicine for various ailments such as cough, small pox, skin lesions, bronchial ailments and toothache. The study was aimed at establishing a safety profile, evaluating phytochemical constituents and some...
ABSTRACT
Incidence and prevalence of type 2 diabetes mellitus (T2DM), with its resultant complications continue to be on the increase. The outcome of management is highly dependent on efficacy, safety and suitability of medicines used concomitantly. An aspect of efficacy/safety that is...
ABSTRACT
Acacia ataxacantha is used in traditional medicine for management of pain and inflammation. Literature survey revealed that the safety and efficacy of such uses have not been scientifically validated. The present study was designed to study the pharmacological and toxicological...
ABSTRACT
The use of medicinal plant extracts to maintain health, prevent or cure various diseases is known since ancient times. However, most times, there is little or no knowledge of the associated possible toxic injuries on vital organs morphology or functions from the use of such pla...
Abstract
The cellular immunity is often suppressed by infection, disease conditions and drug medication that are in continous association with mankind. Combretum micranthum is a plant known for its antioxidant, antimicrobial, anti-inflammatory and various other properties of immune boos...
Abstract
Nigeria has the second highest HIV/AIDS burden in the world with an estimated 3,391,546 people living with HIV and AIDS; an estimated 239,155 people acquired new infections in 2013; and about 174,253 people died from AIDS related illness (s) in 2014. HIV infection causes a chro...
ABSTRACT
Ficus glumosa is widely distributed in Northern part of Nigeria; it has been exploited for both its medicinal and economic importance. It is traditionally used for the treatment of number of ailments including gastrointestinal, respiratory, inflammatory, cardiovascular disorder...
ABSTRACT
This study evaluated some pharmacognostic standards and anti-inflammatory activity of the leaves of Allophylus africanus Beauv (Sapindaceae). The plant has a wide distribution in West Africa, with Nigeria (Mambila Plateau, Calabar) inclusive. It has been used in communities for...
ABSTRACT
Ludwigia abyssinica Rich (Onagraceae) is a plant native to South America but now widely distributed in Africa. It has been exploited for its medicinal and economic importance. It is traditionally used for the treatment of a number of ailments such as cough, skin diseases, sores...
ABSTRACT
Saba comorensis (Boj) Pichon (Apocynaceae) has been used traditionally in various parts of Tropical Africa region as an aphrodisiac, for rheumatism, arthritis, liver disease, jaundice, venereal disease, normal spleen function, as laxative, and purgative. This study is aimed at...
ABSTRACT
Maytenus senegalensis (Celastraceae) is commonly known as thorny staff tree or confettii tree, is of high traditional use among the „Hausa‟ community of Northern Nigeria. Hence the present investigation was to establish the pharmacognostic parameters for the leaves and st...
ABSTRACT
Inflammation has been implicated in virtually all human and animal diseases. It has become the focus of global scientific research, more so, since the currently used anti-inflammatory agents both steroidal and non-steroidal are prone to evoking serious adverse reactions. Stegan...
ABSTRACT
Asthma, which affects an estimated 300 million people worldwide, is an incurable health disorder of a major public health concern globally. The present orthodox therapy for asthma has several drawbacks including many undesirable side effects and high cost of management (especia...
ABSTRACT Curcuma longa are traditionally used for the treatment of ulcers, hepatic disorder, wound healing and boost glucose control. This study assessed the phytochemical compositions (quantitative and qualitative), antibacterial activities of C. longa crude extracts, synthesis and characterisat...
ABSTRACT
The treatment inadequacy and toxicity associated with conventional anti-malarial, antiinflammatory and analgesic drugs calls for the search for alternatives from medicinal plants, particularly. In the present study, alkaloid fraction of Maytenus senegalensis leaf was evaluated...
ABSTRACT
Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants. The urgency generated by in increased rate of stroke, atheroselerosis attributed to prolong use of cyclooxygenase-1 and 2 inhibitors have acceralated...
ABSTRACT
78 This research investigated the phytochemical and anti-inflammatory properties of methanol extract of Crateva adansonii stem bark. Although several edible and non-edible plants parts are used in inflammatory treatment, many record has been found of the use of Crateva ad...
ABSTRACT
Crateva adansonii is a medicinal herb commonly used in parts of Africa because of the side effects of Non-Steroidal Anti-inflammatory Drugs (NSAID), like heart diseases and kidney failure. Inflammation is a major public heart issue in the world but treatment is becoming complex...
Abstract
Nigeria is still battling with the problem of insurgency. Pictures of bloody acts of violence by insurgents are shown. Insurgency attacks cause serious destruction of lives and properties in Nigeria and have continued to cause fear, anxiety, anger, sorrow and pain to the people...
ABSTRACT
Pain is a worldwide problem and is associated with most disease conditions. The properties of herbs used to treat pain were investigated with the aim of confirming their use and finding out some pharmacological properties that may augment their analgesic activity. A total of ei...
ABSTRACT
The search for antimalarial compounds was necessitated by Plasmodium falciparum resistance to most antimalarial drugs. In endemic countries where malaria is prevalent, medicinal plants are often used to treat malaria. In this study, the in vitro antimalarial activities of crude...
Abstract
This study is aimed at determining the status, prevalence and significance of female urogenital schistosomiasis (FUGS) in schistosomiasis endemic population at risk of HIV transmission in Jos, Plateau State. Epidemiological circumstances that predisposed individuals to urogenit...
ABSTRACT
Fish are particularly sensitive to a wide variety of agrochemicals including glyphosate herbicide that may arise from not only deliberate discharge of these chemicals into waterways but also from approved agricultural practices. The toxic effects of glyphosate on Clarias gariep...
ABSTRACT
Erythrophleumivorense isused in traditional medicine for the treatment of convulsion, swellings, body pain and as emetic agents. There is a dearth of scientific information in support of the traditional claims. This study was therefore designed to investigate the analgesic, ant...
ABSTRACT
High records of occurrences of child mortality were documented in ancient Rome and in modern Ibadan. Available studies on ancient Rome focused on the effect of female infanticide on the population, and those on modern Ibadan, concentrated on the effects of cerebral malaria on c...
CHAPTER ONE
INTRODUCTION
1.1 Background of the Study
In this day and age, social media platforms such as Facebook, Twitter, Instagr...
CHAPTER ONE
INTRODUCTION
1.1 Background of the study
The hippocampus, a region situated within the medial temporal...