1. DESIGN AND DEVELOPMENT OF A STARCH-BASED MULTIFUNCTIONAL EXCIPIENT (STARGELASIL) FOR TABLET FORMULATION
ABSTRACT
The concept of co-processing as a particle engineering technique has been used as a tool to improve the functionality of many existing excipients. This study was designed to improve the functionality of cassava starch as excipient for direct compression by coprocessing with gel...
2. SOLID DISPERSION AS AN APPROACH FOR SOLUBILITY AND DISSOLUTION ENHANCEMENT OF IBUPROFEN AND PIROXICAM
ABSTRACT
The aim of this study was to enhance the solubility and hence dissolution rate of two poorly soluble drugs: ibuprofen and piroxicam using Eudragit RS 100 and hydroxymethylpropylcellulose (HPMC) as carriers, by solid dispersion technique and to evaluate the effect of trona (sodi...
3. THE EFFECT OF QUININE-ARTESUNATE CO-ADMINISTRATION ON SOME BIOCHEMICAL PARAMETERS IN PLASMODIUM BERGHEI PARASITIZED SWISS ALBINO MICE AND RATS
ABSTRACT
Malaria has been the leading cause of morbidity and mortality in most Sub-saharan Africa and Southeastern Asia. Combination therapy has been recommended for treatment of malaria and this could lead to drug-drug interaction. This work titled “The effect of Quinine-Artesuna...
4. THE ANTI-INFLAMMATORY ACTIVITY OF Crateva adansonii DICHLOROMETHANE FRACTION.
ABSTRACT
Crateva adansonii is a medicinal herb commonly used in parts of Africa because of the side effects of Non-Steroidal Anti-inflammatory Drugs (NSAID), like heart diseases and kidney failure. Inflammation is a major public heart issue in the world but treatment is becoming complex...
