1. ANTIHYPERGLYCAEMIC AND ANTIBACTERIAL EVALUATION OF METHANOL TUBER EXTRACT OF CHLOROPHYTUM ALISMIFOLIUM BAKER (LILIACEAE)
ABSTRACT
Diabetes mellitus is a metabolic disorder which affects about 346 million people globally. Synthetic antidiabetic agents are expensive and also associated with side effects. In a bid to develop cheaper and safer antidiabetic agents, this study was carried out to determine the e...
2. CHRONOMODULATED NIFEDIPINE ADMINISTRATION AND MICROVASCULAR COMPLICATIONS IN GLIMEPIRIDE-TREATED HYPERGLYCAEMIC RATS
ABSTRACT
Diabetic complications pose increasing public health problems worldwide. Glimepiride, a sulphonylurea is among the most frequently used anti-diabetic drugs, and is often combined with other drugs for the management of type 2 diabetes mellitus. Nifedipine, a calcium channel bloc...
3. PHARMACOLOGICAL INTERACTION BETWEEN ETHANOL EXTRACT OF MORINGA OLEIFERA LEAVES AND METFORMIN IN ALLOXANINDUCED HYPERGLYCAEMIC WISTAR RATS
Abstract
Herbs with anti-diabetic activity could initiate interactions if used concurrently with orthodox drugs. Moringa oleifera is one of such herbs usually taken as an adjunct to orthodox oral hypoglycaemic agents. This study investigated the possible pharmacological interaction betw...
4. TOXICOLOGICAL AND ANTI-HYPERGLYCAEMIC PROPERTIES OF AQUEOUS LEAF EXTRACT OF PERSEA AMERICANA MILL (LAURECEAE) IN NORMOGLYCAEMIC AND ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS
ABSTRACT
Diabetes mellitus has become a global health burden leading to an increase in the search for herbal anti-hyperglycaemic agents as alternative to synthetic ones. Persea americana popularly known as avocado pear have been known for its nutritional and medicinal properties. The le...
5. EFFECTS OF CO-ADMINISTRATION OF SITAGLIPTIN AND ETHANOL LEAF EXTRACT OF MORINGA OLEIFERA LAM. IN ALLOXAN-INDUCED DIABETES MELLITUS AND ITS CHRONIC COMPLICATIONS IN RATS
ABSTRACT
Incidence and prevalence of type 2 diabetes mellitus (T2DM), with its resultant complications continue to be on the increase. The outcome of management is highly dependent on efficacy, safety and suitability of medicines used concomitantly. An aspect of efficacy/safety that is...
6. SOME PHARMACOLOGICAL PROPERTIES OF METHANOL EXTRACT OF ANISOPUS MANNII N.E.Br (ASCLEPIADACEAE) IN ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS
ABSTRACT
Diabetes mellitus is a metabolic disorder that affects carbohydrates, lipids and proteins resulting in sustained hyperglycaemia which could lead to serious organ(s) damage and death. The aim of this study was to investigate some of the pharmacological properties of the methanol...
