1. A STUDY ON GARLIC (Allium sativum L.) MEAL AND ITS EFFECT AS A FEEDING INGREDIENT IN BROILER CHICKEN DIET
BACKGROUND OF THE STUDY
Because of the alleged harmful consequences of antibiotic resistance on human health, there is growing demand to decrease or abolish the use of antibiotics in poultry feed (Javandel et al., 2008). A nationwide regulation prohibit...
2. FEEDS AND FEEDING OF SHEEP AND GOAT
ABSTRACT
Comparisons were made between 25 Ethiopian rams and 25 Galla goats for voluntary intake Two separate studies to evaluate alternative methods of processing Acacia nilotica pods and level of replacement of cotton seed cake with Acacia pods; an...
3. FACTORS AFFECTING QUALITY OF LABORATORY SERVICES AT INFECTIOUS DISEASES HOSPITAL, KANO – NIGERIA
ABSTRACT
Quality laboratory services are essential and integral part of improved health outcome especially for HIV/AIDS patients on ART. We aimed to assess clients‘ satisfaction with laboratory services as an indicator of quality and factors affe...
4. ANTI-DIARRHOEAL AND SUBCHRONIC TOXICITY STUDIES ON METHANOL STEM BARK EXTRACT OF IRIVINGIA WOMBOLU VERMOESEN (IRVINGIACEAE) IN LABORATORY ANIMALS
Abstract
Irvingia wombolu is one of the herbal plants used as food for its nutritional values. It is also used as medicinal plant in the south-south and south-eastern part of Nigeria for the management of diarrhoea and other ailments. Although these medicinal plants are believed to be h...
5. ANTICONVULSANT STUDIES OF THREE SYNTHESIZED DICHLOROSUBSTITUTED PHENYL PROPANAMIDES AND THEIR ACTION ON VOLTAGE-GATED SODIUM CHANNELS (Nav1.6)
Abstract
The field of antiepileptic drug development has become dynamic, affording many promising research opportunities. Continued efforts are being made in the development of antiepileptic drugs employing a range of strategies, including modification of the structures of existing drug...
6. ANTIDIARRHOEAL AND TOXICITY STUDIES ON METHANOL LEAF EXTRACT OF COMBRETUM HYPOPILINUM DIELS (COMBRETACEAE) IN MICE AND RATS
ABSTRACT
The plant Combretum hypopilinum has been used in traditional medicine to treat diarrhoea and other gastrointestinal diseases. This study aimed to investigate the antidiarrhoeal activity and toxicity profile of the methanol leaf extract of Combretum hypopilinum (MECH) in mice an...
7. ANXIOLYTIC PROPERTIES OF MITRACARPUS VILLOSUS (SW) DC.LEAF EXTRACTS IN MICE AND RATS
ABSTRACT
The leaf of Mitracarpusvillosus (Sw.) DC. (Rubiaceae) is used in West African folk medicine for the management of a plethora of stress-related diseases including headaches and toothaches. In this study, preliminary phytochemical analysis of the ethylacetateleaf extract of Mitra...
8. EFFECT OF CHRONOMODULATED ARTESUNATE ON RENAL AND HAEMATOLOGICAL TOXICITY IN CISPLATIN-TREATED WISTAR RATS
ABSTRACT
Cisplatin is a non-cell-cycle dependent chemotherapeutic agent used in the treatment of several common solid tumours. However, an array of serious toxicities in various organs and systems limit its therapeutic use. Artesunate, a semisynthetic derivative of artemisinin is the re...
9. EFFECTS OF ADMINISTRATION OF CARBAMAZEPINE, PHENYTOIN AND THEIR COMBINATION ON NEUROBEHAVIOURAL, COGNITIVE HAEMATOLOGICAL AND SERUM BIOCHEMICAL CHANGES IN ALBINO RATS
ABSTRACT
The aim of the study was to evaluate the neurobehavioural patterns, cognitive functions and haemato-biochemical changes following the administration of carbamazepine (CBZ), phenytoin (PHE) and their combination. Forty, apparently healthy adult male Albino rats weighing between...
10. HYPOTENSIVE ACTIVITY AND TOXICOLOGICAL PROFILE OF STEM BARK EXTRACT OF SYZYGIUM GUINEENSE (Willd, D.C. Myrtaceae) IN LABORATORY ANIMALS
ABSTRACT
Hypertension of unknown cause is called essential or primary hypertension while hypertension of a known cause is called secondary hypertension. Hypertension is called a silent killer because it is usually asymptomatic. It is a global problem affecting 1 in 3 adults in the Unite...
11. PHARMACOTHERAPEUTICS OF MOOD DISORDERS IN PATIENTS ATTENDING NEURO PSYCHIATRIC CLINIC, AHMADU BELLO UNIVERSITY TEACHING HOSPITAL (ABUTH) ZARIA-NIGERIA
ABSTRACT
Mood disorders (primary major depressive disorder and bipolar affective disorder) constitute one of the world’s greatest public health problems and are associated with significant reductions in productivity, health and longevity. This study involved a retrospective analys...
12. SOME NEUROPHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE ETHANOLIC LEAF EXTRACT OF CUSSONIA BARTERI SEEMAN (ARALIACEAE) IN LABORATORY ANIMALS
ABSTRACT
Cussonia barteri is used in traditional medicinefor the management of convulsion and epilepsy, especially in children in Ghana and Nigeria. Literature survey revealed that the safety and efficacy of such important medicinal plant have not been scientifically validated. In the p...
13. SOME PHARMACOLOGICAL STUDIES ON THE ETHANOLIC STEM BARK EXTRACT OF PTEROCARPUS ERINACEUS POIR (FABACEAE)
ABSTRACT
Some pharmacological effects of the 70% ethanolic stem bark extract of Pterocarpus erinaceus were investigated in experimental animals. Preliminary Phytochemical studies of the ethanolic extract revealed the presence of Tannins, Carbohydrates, Proteins & Amino acids, Flavon...
14. TOXICOLOGICAL AND ANTI-HYPERGLYCAEMIC PROPERTIES OF AQUEOUS LEAF EXTRACT OF PERSEA AMERICANA MILL (LAURECEAE) IN NORMOGLYCAEMIC AND ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS
ABSTRACT
Diabetes mellitus has become a global health burden leading to an increase in the search for herbal anti-hyperglycaemic agents as alternative to synthetic ones. Persea americana popularly known as avocado pear have been known for its nutritional and medicinal properties. The le...
15. TOXICOLOGICAL ASSESSMENT OF THE METHANOL LEAF EXTRACT OF SECURINEGA VIROSA(ROXB EX. WILLD) IN WISTAR RATS
ABSTRACT
Securinega virosa is one of the African medicinal plants described as a true “cure all” among traditional practitioners. Different parts of Securinega virosa have been used in the management of different disorders in Nigeria and other parts of the world. There is th...
16. DIURETIC AND TOXICITY STUDIES OF METHANOL STEM BARK EXTRACT OF SPONDIAS MOMBIN LINN (ANACARDIACEAE) IN RATS
ABSTRACT
Spondias mombin belongs to the family Anacardiacae. All parts of the tree are reported to be medicinally useful. The fruit juice is drunk as a diuretic and febrifuge. The main aim of the study is to determine the diuretic activity and toxicity of methanol stem bark extract of S...
17. EFFECTS OF DETOXIFICATION ON SOME PHARMACOLOGICAL PROPERTIES OF JATROPHA CURCAS LINN. (EUPHORBIACEAE) SEED OIL IN LABORATORY ANIMALS
Abstract
Jatropha curcas seed oil is a known energy source in biodiesel which but for its toxicity, also has potential of being used as food and in the pharmaceutical / cosmetic industries. This study was designed to detoxify solvent and mechanically extracted J. curcas oils and to asce...
18. EVALUATION OF THE GASTROPROTECTIVE AND SUB-CHRONIC TOXICITY OF METHANOL STEM BARK EXTRACT OF XIMENIA AMERICANA LINN (OLACACEAE) IN MALE WISTAR RATS
Abstract
Ximenia americana is a plant used traditionally in northern parts of Nigeria for treatment of leprotic ulcers and mouth ulcers in addition to other medicinal uses. It contains flavanoids, saponins, tannins among others that has been reported to possess gastroprotective potentia...
19. GASTRO-INTESTINAL MUCOSAL PROTECTIVE PROPERTIES AND TOXICITY STUDIES ON THE METHANOL ROOT EXTRACT OF WALTHERIA INDICA LINN. (STERCULIACEAE) IN LABORATORY ANIMALS
ABSTRACT
Many countries worldwide including Nigeria use different parts of Waltheria indica (leaves, stem-barks, roots and whole plants) to treat various ailments. In Nigeria, Waltheria indica is used to treat gastro-intestinal ulcers, pain, inflammation, diarrhoea, conjunctivitis, anae...
20. HAEMATOLOGICAL, SERUM BIOCHEMICAL AND PATHOLOGICAL CHANGES IN JAPANESE QUAIL (COTURNIX COTURNIX JAPONICA) EXPERIMENTALLY INFECTED WITH SALMONELLA ENTERICA SEROVAR GALLINARUM
ABSTRACT
A total of 160 (108 males and 52 females) Japanese quails (Coturnix coturnix japonica) were used for the experiment. The quails were obtained at the age of four weeks from the Poultry Unit of the National Veterinary Research Institute, Vom, Plateau State, Nigeria. They were ran...
21. TOXICITY STUDIES OF THE ETHANOLIC STEM BARK EXTRACT OF RANDIA NILOTICA STAPF. IN RATS
ABSTRACT
The use of medicinal plant extracts to maintain health, prevent or cure various diseases is known since ancient times. However, most times, there is little or no knowledge of the associated possible toxic injuries on vital organs morphology or functions from the use of such pla...
22. EFFECT OF AQUEOUS ETHANOL LEAF EXTRACT OF COMBRETUM MICRANTHUM G. DON (COMBRETACEAE) ON SOME INDUCED SYSTEMIC INFLAMMATORY IMMUNE RESPONSE SYNDROMES IN MICE AND RATS
Abstract
The cellular immunity is often suppressed by infection, disease conditions and drug medication that are in continous association with mankind. Combretum micranthum is a plant known for its antioxidant, antimicrobial, anti-inflammatory and various other properties of immune boos...
23. EFFECTS OF CO-ADMINISTRATION OF PROMETHAZINE AND ARTEMETHER-LUMEFANTRINE IN PLASMODIUM berghei berghei INFECTED MICE
ABSTRACT
Malaria is the 2nd leading cause of death from infectious diseases in Africa, after HIV/AIDS. It is a major public health problem in Nigeria where it accounts for most cases of hospital visits and deaths than any other country in the world. This study evaluated the effects of c...
24. SOME NEUROPHARMACOLOGICAL STUDIES OF EXTRACT AND FRACTIONS OF CRINUM ZEYLANICUM(L.) (AMARYLLIDACEAE)BULB IN LABORATORY ANIMALS
ABSTRACT
Crinum zeylanicum is a medicinal plant used in folk medicine for management of general debility, infantile seizures and pain. Some neuropharmacological effects of methanolic bulb extract of Crinum zeylanicum were studied in laboratory animals.The Phytochemical screening of the...
25. TOXICITY STUDIES ON N-HEXANE AND METHANOL LEAF AND METHANOL SEED EXTRACTS OF JATROPHA CURCAS LINN. IN CHICKS AND MICE
Abstract
Jatropha curcas is a toxic plant commonly used as food and remedy for several diseases. This study was designed to evaluate the protective and therapeutic effects of sodium nitrite, sodium thiosulphate, penicillamine, ethylene diamine tetra-acetic acids (EDTA) and atropine agai...
26. EVALUATION OF LEAF BASE EXTRACT OF SORGHUM BICOLOR (FAMILY: GRAMINEAE; POACEAE) FOR HAEMATOLOGICAL, IMMUNOMODULATORY AND OTHER PHARMACOLOGICAL ACTIVITIES
ABSTRACT
Sorghum bicolor is an annual plant having its different parts widely used ethnomedicinally for different ailments, which includes blood stimulation and body defence. A number of clinical conditions like cancer, surgery, certain drugs, HIV/AIDS and various stressors affect diffe...
27. THE EFFECT OF QUININE-ARTESUNATE CO-ADMINISTRATION ON SOME BIOCHEMICAL PARAMETERS IN PLASMODIUM BERGHEI PARASITIZED SWISS ALBINO MICE AND RATS
ABSTRACT
Malaria has been the leading cause of morbidity and mortality in most Sub-saharan Africa and Southeastern Asia. Combination therapy has been recommended for treatment of malaria and this could lead to drug-drug interaction. This work titled “The effect of Quinine-Artesuna...
28. ANTIBACTERIAL ACTIVITY OF HELIANTHUS ANNUUS SEEDS EXTRACT ON SALMONELLA SPECIES AND ESCHERICHIA COLI
ABSTRACT Medicinal plants contain active ingredients with therapeutic values. Helianthus annuus L (Asteraceae) commonly referred to as “sunflower” has been reportedly used in managing and treating some ailments over the years. This study investigated the in vitro and in vivo antibacte...
29. NUTRITIONAL EVALUATION OF CEREAL AND LEGUME-BASED COMPLEMENTARY DIETS USED IN JOS, PLATEAU STATE
ABSTRACT
Three multimix complementary diets were prepared from local foodstuffs i.e. maize (Zea mays), acha grain (Digitaria exilis) rice (Sativa oryza), sorghum (Sorgum bicolar), millet (Pennisatum typhoides), groundnut (Arachis hypogea), bambaranut (V-oadzeia subterranea), sesame (Ses...
30. COMPARATIVE EFFECT OF COMMERCIAL FEED AND FORMULATED DIETS ON THE GROWTH AND BIOCHEMICAL PARAMETERS OF HETEROBRANCHUS BIDORSALIS (CATFISH) FINGERLINGS
ABSTRACT
Fish farming is a major viable solution to the problem of protein inadequacy in Nigeria but the high cost of feed remains a major obstacle. This study evaluated the comparative effect of commercial feed and formulated diets on the growth and biochemical parameters of Heterobran...
31. EVALUATION OF HAEMATOLOGICAL PROFILES OF WOMEN AND CHILDREN INFECTED WITH MALARIAL PARASITES IN BOSSO AND PAIKORO LOCAL GOVERNMENT AREAS OF NIGER STATE
ABSTRACT
Malaria continues to be a major public health challenge especially in the African region despite the availability of anti malarial drugs and the application of several preventive strategies such as the use of insecticide treated nets, indoor residual spraying, and intermittent...
32. ETHNOPHARMACOLOGICAL AND PHYTOCHEMICAL PROPERTIES OF SOME PLANTS USED IN THE MANAGEMENT OF PAIN
ABSTRACT
Pain is a worldwide problem and is associated with most disease conditions. The properties of herbs used to treat pain were investigated with the aim of confirming their use and finding out some pharmacological properties that may augment their analgesic activity. A total of ei...
33. TOXIC EFFECTS OF GLYPHOSATE ON THE BEHAVIOUR, HAEMATOLOGY, HISTOPATHOLOGY AND GROWTH OF THE AFRICAN CATFISH, Clarias gariepinus (Burchell, 1822) JUVENILES
ABSTRACT
Fish are particularly sensitive to a wide variety of agrochemicals including glyphosate herbicide that may arise from not only deliberate discharge of these chemicals into waterways but also from approved agricultural practices. The toxic effects of glyphosate on Clarias gariep...
34. EFFECT OF SPROUTING ON THE FORMULATION OF WEANING DIETS FROM BAMBARA NUT (Vigna. subterranean) AND SORGHUM (Sorghum bicolor)
ABSTRACT
Protein energy malnutrition (PEM) accounts for over 50 % mortality among weaning children globally. Fortification and formulation had been used to supply some of the nutritionally deficient nutrients in diets of malnourished children. Sorghum is generally used as weaning foods...
35. CD4+ CELL COUNT AND LEVELS OF SOME CYTOKINES AND HAEMATOLOGICAL PARAMETERS OF PREGNANT WOMEN ATTENDING NNAMDI AZIKIWE UNIVERSITY TEACHING HOSPITAL, NNEWI
Statement of the Problem
Previous studies have shown that normal pregnancy is associated with profound changes in haematological profile which appears to be pathological in the non-pregnant state (Chandra, 2012), coagulation profile, which may lead to excessive maternal bleeding during...
36. EFFECT OF WOOD SMOKE (BIOMASS) ON SOME LUNG FUNCTION TESTS, CARDIOVASCULAR PARAMETERS AND HAEMATOLOGICAL INDICES OF WOMEN IN ZARIA, NIGERIA
ABSTRACT
Wood smoke is a complex mixture of substance produced during the combustion of wood. The major emissions from wood stoves are carbon monoxide, organic gases, particulate matter, oxides of nitrogen and sulphur. Toxic compounds as well as carcinogenic substances are also produced...
