1. EFFECT OF VITAMINS C AND E ON MEMORY IN ADULT MICE
Vitamin C, also known as L-ascorbic acid, is a water-soluble vitamin that is naturally present in some foods, added to others, and available as a dietary supplement and is destroyed by heat or reduced by prolonged storage (Weinstein et al., 2001). Humans, unlike most...
2. EVALUATION OF ANTIOXIDANT POTENTIAL OF MONODORA MYRISTICA (AFRICAN NUTMEG)
BACKGROUND OF THE STUDY
Lipid oxidation is one of the major reasons that food deteriorate and is caused by the reaction of fat and oil with molecular oxygen, leading to off-flavours that are generally called rancidity(Basturk et al., 2...
3. THE ECONOMIC IMPORTANCE OF FERMENTATION
Background of the Study
Since fruit ferments naturally, fermentation precedes human history. However, human began to take control of fermentation process art some points in time. There is strongest evidence that people were fermenting beverage.
...4. A COMPARATIVE REVIEW ON MICRO-ORGANISM ASSOCIATED WITH THE SPOILAGE OF BANANA
Bacteria do not seem important in the initial spoilage of whole fruits like banana instead such spoilage often is initiated by molds. These organisms have enzymes that contribute to the weakening and penetration of the protective outer skin. Many microorganisms have been isolate...
5. AN ANTIMICROBIAL ANALYSIS AND PHYTOCHEMICAL OF Mangifera indica AND Carica papaya LEAVES
BACKGORUND TO THE STUDY
It is well known that in order for a plant to protect itself, it creates certain compounds that can also protect humans from sickness. Today, there are approximately 4000 distinct phytochemicals that have the potential to alter disorders such as...
6. AN ASSESSMENT INTO THE FREQUENCY OF URINARY TRACT PARASITES IN PATIENTS
Background to the Study
An infection of any region of the urinary system is referred to as a urinary tract infection (often abbreviated as UTI). The kidneys, ureters, bladder, and urethra are the components that make up the urinary tract. Any component...
7. AN INVESTIGATION ON THE COMMONESS OF URINARY TRACT PARASITES AMONG PATIENTS
Background to the Study
An infection of any region of the urinary system is referred to as a urinary tract infection (often abbreviated as UTI). The kidneys, ureters, bladder, and urethra are the components that make up the urinary tract. Any component...
8. ANALYSIS OF SOME MINERAL CONTENTS OF COCONUT WATER
Background of the Study
The coconut (Cocos nucifera L.) is a tropical plant which belongs to the order Arecales and family Arecaceae. It is widely grown in about 90 tropical regions of the world (Peggy, 2007).Every part can be utilized roots, husk, leaves and fruit. The...
9. AN EVALUATION OF THE APHRODISIAC AND FERTILITY ENHANCING EFFECT OF THE METHANOLIC ROOT EXTRACT OF CISSUS POPULNEA Guill.And Perr. (Vitaceae)
ABSTRACT
Aphrodisiac activity of Cissus populnea was assessed using physical, biochemical and psychological methods. Rats were randomized into five groups of six rats. The first group received normal saline (10ml/kg), the second, third and fourth groups received extract doses of 250mg/k...
10. ANALGESIC, ANTI-INFLAMMATORY AND TOXICITY STUDIES ON METHANOLIC LEAF EXTRACT OF ROTHMANNIA LONGIFLORA SALISB (RUBIACEAE) IN RATS AND MICE
ABSTRACT
The herbalists in several African Countries have used Rothmannia longiflora decoctions as febrifugal and analgesic agent. The present study examined the analgesic, anti-inflammatory and toxicological profile of the methanolic extract of the plant in experimental animals. The pr...
11. DESIGN, SYNTHESIS, ANTIMALARIAL EVALUATION AND COMPUTATIONAL STUDIES OF SOME CHALCONE DERIVATIVES
ABSTRACT
Inspired by the previous findings on the structural requirements needed for good antimalarial activity by chalcones against Plasmodium proteases, seventeen chalcone derivatives were designed and synthesized using Claisen-Schmidt condensation of appropriate aldehydes and methyl...
12. ANTIHYPERGLYCAEMIC AND ANTIBACTERIAL EVALUATION OF METHANOL TUBER EXTRACT OF CHLOROPHYTUM ALISMIFOLIUM BAKER (LILIACEAE)
ABSTRACT
Diabetes mellitus is a metabolic disorder which affects about 346 million people globally. Synthetic antidiabetic agents are expensive and also associated with side effects. In a bid to develop cheaper and safer antidiabetic agents, this study was carried out to determine the e...
13. ANTI-HYPERLIPIDEMIC POTENTIAL OF VITEX DONIANAETHANOLEXTRACTS ON POLOXAMER 407 INDUCED HYPERLIPIDEMIC AND NORMAL RATS
ABSTRACT
Anti-hyperlipidemic potential of extracts (aqueous, 70% methanol, 70% ethanol and 70%, acetone) of Vitexdoniana leaves, stem bark and root bark on poloxamer 407 induced hyperlipidemic and normal rats was investigated. Phytochemical screening of the extracts revealed the presenc...
14. HEPATOPROTECTIVE AND WOUND HEALING PROPERTIES OF METHANOLIC STEM BARK EXTRACT OF FICUS PLATYPHYLLA Del. Holl (MORACEA)
ABSTRACT
Ficus platyphylla (Fp) is a medicinal plant that is widely used in Northern part of Nigeria for the management of skin problems such as eczema and topical application of its gum (latex) to wounds. It is also used for treating malaria and psychosis. Its antioxidant, hepatoprotec...
15. SOLID DISPERSION AS AN APPROACH FOR SOLUBILITY AND DISSOLUTION ENHANCEMENT OF IBUPROFEN AND PIROXICAM
ABSTRACT
The aim of this study was to enhance the solubility and hence dissolution rate of two poorly soluble drugs: ibuprofen and piroxicam using Eudragit RS 100 and hydroxymethylpropylcellulose (HPMC) as carriers, by solid dispersion technique and to evaluate the effect of trona (sodi...
16. EFFECTS OF VITAMIN B COMPLEX THERAPY ON TEMPORAL VARIATION IN GENTAMICIN NEPHROTOXICITY IN WISTAR RATS
ABSTRACT
The efficacy and toxicity of several drugs is circadian-rhythm dependent, and this can be exploited as a guide to ameliorate such drug toxicity. Gentamicin is an aminoglycoside antibiotic used in treatment of a variety of infections. Its use is however limited by its associated...
17. EVALUATION OF THE GASTROPROTECTIVE AND SUB-CHRONIC TOXICITY OF METHANOL STEM BARK EXTRACT OF XIMENIA AMERICANA LINN (OLACACEAE) IN MALE WISTAR RATS
Abstract
Ximenia americana is a plant used traditionally in northern parts of Nigeria for treatment of leprotic ulcers and mouth ulcers in addition to other medicinal uses. It contains flavanoids, saponins, tannins among others that has been reported to possess gastroprotective potentia...
18. SOME PHARMACOLOGICAL PROPERTIES OF METHANOL EXTRACT OF ANISOPUS MANNII N.E.Br (ASCLEPIADACEAE) IN ALLOXAN-INDUCED HYPERGLYCAEMIC WISTAR RATS
ABSTRACT
Diabetes mellitus is a metabolic disorder that affects carbohydrates, lipids and proteins resulting in sustained hyperglycaemia which could lead to serious organ(s) damage and death. The aim of this study was to investigate some of the pharmacological properties of the methanol...
19. TOXICITY STUDIES OF THE ETHANOLIC STEM BARK EXTRACT OF RANDIA NILOTICA STAPF. IN RATS
ABSTRACT
The use of medicinal plant extracts to maintain health, prevent or cure various diseases is known since ancient times. However, most times, there is little or no knowledge of the associated possible toxic injuries on vital organs morphology or functions from the use of such pla...
20. PHYTOCHEMICAL AND INHIBITION STUDIES OF GARCINIA KOLA HECKEL (GUTTIFERAE) SEED EXTRACTS ON SOME KEY ENZYMES INVOLVED WITH DIABETES
ABSTRACT
Garcinia kola is an Angiosperm belonging to the family Guttiferae. It is known in commerce as bitter kola. The plant seeds have been used in the treatment of a wide range of diseases including diabetes, and its importance in folkloric medicine as a purgative, mastcatory, aphrod...
21. SOME NEUROPHARMACOLOGICAL STUDIES OF EXTRACT AND FRACTIONS OF CRINUM ZEYLANICUM(L.) (AMARYLLIDACEAE)BULB IN LABORATORY ANIMALS
ABSTRACT
Crinum zeylanicum is a medicinal plant used in folk medicine for management of general debility, infantile seizures and pain. Some neuropharmacological effects of methanolic bulb extract of Crinum zeylanicum were studied in laboratory animals.The Phytochemical screening of the...
22. STUDIES ON IN-VIVO ANTIOXIDANT AND HEPATOPROTECTIVE PROPERTIES OF CITRUS SINENSIS (L.) OSBECK PEEL EXTRACT IN WISTAR RATS
ABSTRACT
Citrus sinensis is the commonest, most widely cultivated and consumed citrus fruit. Large amounts of peel wastes are formed when citrus is consumed or processed; and suitable methods have to be adopted to utilize these waste materials for conversion into value-added products. F...
23. PREVALENCE AND ANTIMICROBIAL SUSCEPTIBILITY PROFILE OF BACTERIAL ISOLATES FROM CASES OF BACTERIURIA IN ABUJA AND ENVIRON
ABSTRACTS
Urinary tract infections (UTI) are systemic infections that pose great problem to the health care delivery system worldwide. More importantly, the uropathogenic isolates are becoming more resistant to commonly used antimicrobial agents. In order to evaluate the extent of signi...
24. THE EFFECT OF QUININE-ARTESUNATE CO-ADMINISTRATION ON SOME BIOCHEMICAL PARAMETERS IN PLASMODIUM BERGHEI PARASITIZED SWISS ALBINO MICE AND RATS
ABSTRACT
Malaria has been the leading cause of morbidity and mortality in most Sub-saharan Africa and Southeastern Asia. Combination therapy has been recommended for treatment of malaria and this could lead to drug-drug interaction. This work titled “The effect of Quinine-Artesuna...
25. ANTIMICROBIAL EFFECTS OF HONEY AND ITS SPECIFIC ACTIONS ON CELL WALLS, MEMBRANES AND ENZYMES OF SOME MICROBIAL PATHOGENS
ABSTRACT
Antimicrobial agents of plant origin have enormous therapeutic potentials. Honey, which is a product of plant, is a sugary substance produced by bee from the nectar of flower. It has been an age long antimicrobial therapy for wounds and burns. The aim of this study was to deter...
26. ANTITRYPANOSOMAL EFFECT OF CRUDE SCORPION VENOM EXTRACT IN TRYPANOSOMA EVANSI INFECTED SWISS ALBINO RATS
ABSTRACT Despite the control measures against trypanosomiasis over the past few decades, the disease still contributes to the current economic losses and socio-political crises in the sub-Saharan Africa. The recent interest of chemotherapists in aggressive search for novel antitrypanosomal drug a...
27. CARDIO PROTECTIVE ACTIVITIES OF N-HEXANE EXTRACT OF DESMODIUM VELUTINUM STEM ON ALBINO WISTER RAT
ABTRACT
This study evaluates the cardio protactive effect of N-hexane extract of Desmodium Velutinum stem on albino wister rat. Rats used in this study were grouped into four and each group was fed differentely. Rats in group one, three, and four wre fed with the aid of a syringe withou...
28. PRELIMINARY INVESTIGATION ON EFFECTS OF BURANTASHI EXTRACT ON LIVER ENZYMES OF AIBINO MALE AND FEMALE WHISTAR RATS.
ABSTRACT
This work was carried out to investigate the effects of Burantashi extract on liver enzymes of albino male and female whistar rats. Burantashi is a popular seasoning agent to barbecued meat (suya) in Nigeria,mostly found in the northern part of the Nigeria. Liver Enzymes are th...
29. THE EFFECT OF ETHANOL EXTRACT OF DESMODIUM VELUTINUM STEM ON SOME MARKER EMZYME IN LIVER OF ALBINO WISTAR RATS
Abstract
Present investigations were carried out on the effect of ethanol extract of Desmodium velutinum stem on some liver enzymes of albino wistar rats fed with 8 high fat from cow‟s brain. Twelve healthy albino wistar rats were divided into four groups. Group I rats were fed with bal...
30. CHARACTERIZATION OF UREASE OF BACTERIAL ISOLATES FROM CEMENT FOR CONCRETE ENHANCEMENT
ABSTRACT
Ureases are a group of enzymes that hydrolyse urea producing carbon dioxide and ammonia. Urease producing bacteria have shown their importance in microbially induced calcium carbonate precipitation in the construction industry. This study focused on the characterization of bact...
31. STUDIES ON YERSINIOSIS IN HUMAN AND SELECTED ANIMAL POPULATIONS IN JOS AND ITS ENVIRONS
ABSTRACT
Yersinia enterocolitica and Yersinia pseudotuberculosis are important food and water borne pathogens that has recently emerged world wide. This study was aimed at characterizing the prevalence of Yersinia enterocolitica and Yersinia pseudotuberculosis in human and selected anim...
32. EVALUATION OF MOLLUSCICIDAL ACTIVITIES OF CRUDE AND ALKALOIDAL FRACTION OF ANOGEISSUS LEIOCARPUS (AFRICAN BITCH) AND PSEUDOCEDRELA KOTSCHYI (DRY ZONE CEDAR) ON VECTOR OF SCHISTOSOMIASIS
ABSTRACT
Over the years, the use of plant-based molluscicides has received substantial consideration in the satisfaction for cost-effective alternatives to chemotherapy and synthetic molluscicides in schistosomiasis control. This study was aimed at evaluating the molluscicidal potential...
33. IN VIVO EFFICACY OF METHANOLIC EXTRACTS OF ROOT AND LEAF OF Morinda lucida IN Plasmodium berghei - INFECTED MICE
ABSTRACT
Therapeutic effects of the methanolic root extract and a combination of leaf and root extracts of Morinda lucida were evaluated for antiplasmodial activities. The phytochemical screening of the methanolic root extract showed the presence of saponins, flavonoids, alkaloids, phen...
34. CHARACTERISTICS OF SOME HYDROLYTIC ENZYMES AND BIOPULPING POTENTIAL OF FUNGAL ISOLATES FROM SELECTED WOOD SAMPLES IN SOUTHWESTERN NIGERIA
Abstract
Pulping industry is both labour and energy intensive but in Nigeria, electricity supply is unstable. This has contributed to the near collapse of the Nigerian paper and pulp industry despite the rich forest resources in southwestern Nigeria. Use of alternative energy sources su...
