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1. GEOGRAPHICAL INFORMATION SYSTEM BASED HYDROLOGICAL MODELLING OF CLIMATE CHANGE VARIABLES ON HADEJIA RIVER SUB-BASIN, NIGERIA

ABSTRACT

Soil and Water Assessment Tool (SWAT) and Geographical Information System (GIS) based hydrological modelling was applied to Hadejia River Sub-basin- an integral of the Chad Basin in the Northern Nigeria- to determine the impacts of land use/cover dynamics on the hydrological re...

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2. RELIABILITY BASED CALIBRATION OF PARTIAL SAFETY FACTOR ON CHARACTERISTICS STRENGTH OF STEEL REINFORCEMENT BARS

ABSTRACT

In the calibration of partial safety factor of steel reinforcement bars conducted in this study, necessary parameters (i.e. steel diameter, area, yield strength, ultimate strength, and elongation) needed for the calibration were obtained from the steel testing laboratory, Depar...

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3. COMPARATIVE RELATIVE BIOAVAILABILITY STUDIES OF SIX BRANDS OF OFLOXACIN MARKETED

ABSTRACT

This study was aimed at assessing the comparative bioavailability of six brands of ofloxacin marketed in Zaria. Comparative bioavailability studies of six brands of ofloxacin marketed in Zaria was successfully conducted. Quality assessment was conducted on the randomly selected...

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4. COMPARATIVE BIOEQUIVALENCE STUDIES OF SOME SELECTED BRANDS OF CIPROFLOXACIN TABLETS MARKETED IN NIGERIA

ABSTRACT

Comparative bioequivalence studies of six selected brands of ciprofloxacin tablets was successfully conducted. In-vitro quality control studies were carried out on six randomly selected brands of ciprofloxacin to establish identity, weight uniformity, friability, crushing stren...

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5. COMPARATIVE IN-VITRO BIOEQUIVALENCE STUDIES OF DIFFERENT SAMPLES OF TINIDAZOLE TABLETS

ABSTRACT

Health care professionals are faced with a large number of multisource products from which therapeutically equivalent products are being selected for various reasons. Consequently, an increased availability and use of generic products has been seen during the last four decades....

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6. COMPARATIVE IN VITRO BIOEQUIVALENCE EVALUATION OF SIX BRANDS OF AMOXICILLIN CAPSULE MARKETED IN DUTSE, JIGAWA STATE, NIGERIA

ABSTRACT

Comparative in vitro bioequivalence study of biopharmaceutics class I and III drugs hadgained prominence in recent times. In vitro bioequivalence offered many benefits compared to conventional in-vivobioequivalence studies, due to its reduced cost and time of product release as...

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7. DEVELOPMENT AND VALIDATION OF THREE NEW SPECTROPHOTOMETRIC METHODS FOR THE DETERMINATION OF LAMIVUDINE IN PURE AND PHARMACEUTICAL DOSAGE FORMS

ABSTRACT

In this study three rapid, simple, accurate, economical and reproducible spectrophotometric methods for the quantitative determination of lamivudine in pure form and tablet formulations were developed and validated. The first method is based on dissolution of standard lamivudin...

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8. DEVELOPMENT AND VALIDATION OF FOUR NEW UVSPECTROMETRIC METHODS FOR THE DETERMINATION OF ISONIAZID (INH) IN PURE AND TABLET DOSAGE FORMS

ABSTRACT

Tuberculosis (TB) is a serious infectious disease which is on increase since emergence of human immunodeficiency virus (HIV) leading to TB/HIV co infection, causing complications and treatment failure. Isoniazid is a first line drug for the treatment of TB therefore it is impor...

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9. EFFECT OF CAFFEINE ON PHARMACOKINETICS OF PARACETAMOL IN HEALTHY HUMAN VOLUNTEERS: A CASE STUDY OF PANADOL EXTRA®

ABSTRACT

Acetaminophen or paracetamol is an analgesic and anti-pyretic agent widely used for treatment of headaches, minor pains and in combination with other medications like cold remedies and opoid analgesics. Individuals with headaches and minor pains tend to use paracetamol with caf...

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10. PRELIMINARY PHYTOCHEMICAL SCREENING, QUALITY ASSESSMENT AND MINERAL CONTENT DETERMINATION OF SELECTED BRANDS OF GREEN TEA MARKETED IN NIGERIA

ABSTRACT

Green tea in its purest and most unadultered form has always influenced human health for generations. Though green tea is not officially recognized as a medical agent, it is one of the most researched plant-based remedies with possible benefits including antioxidant activity, s...

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11. EFFECT OF GREEN TEA (CAMELLIA SINENSIS) ON THE PHARMACOKINETIC PROFILE OF CEPHALEXIN IN HEALTHY HUMAN VOLUNTEERS

ABSTRACT

Tea is a herb commonly consumed globally. Herbs are often taken concurrently with conventional medicines which results in increased potential of drug-herb interactions, and this may have important clinical significance based on an increasing number of reports of such interactio...

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12. EFFECT OF RANITIDINE ON PHARMACOKINETIC PARAMETERS OF METRONIDAZOLE IN HEALTHY HUMAN VOLUNTEERS

ABSTRACT

Pharmacokinetics is the study of the time course of drug movement in the body during absorption, distribution, metabolism and elimination.Drug interactions are pharmacodynamic, pharmacokinetic, or clinical responses to the administration of a drugcombination that differs from t...

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13. EFFECTS OF ENVIRONMENTAL EXPOSURE ON THE PHARMACOKINETICS OF CIPROFLOXACIN TABLET IN HEALTHY HUMAN VOLUNTEERS

ABSTRACT

Ciprofloxacin is a flouroquinololone antibiotic that is commonly prescribed empirically in Nigeria due to its broad spectrum of activity. However, the drug product is illegally handled by drug hawkers that allow the drug to be exposed to some environmental forces which may affe...

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14. THE EFFECT OF VITAMIN C ON PHARMACOKINETIC PARAMETERS OF CHLOROQUINE IN HEALTHY HUMAN VOLUNTEERS

ABSTRACT

This study was undertaken to compare the effect of vitamin C on the pharmacokinetics of chloroquine using human volunteers. Quality control studies for both chloroquine and vitamin C; identification test, assay, weight variation, friability, disintegration time and dissolution...

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15. EFFECTS OF CHLORPHENIRAMINE ON THE PHARMACOKINETICS OF ASCORBIC ACID IN HEALTHY MALE VOLUNTEERS

ABSTRACT

Ascorbic acid is a vitamin commonly used in the treatment of common cold and scurvy. It interacts with some drugs during absorption from the gastrointestinal tract, in the systemic circulation or during metabolism in the liver. However, interaction between ascorbic acid and chl...

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16. DESIGN_AND IMPLEMENTATION OF LIGHTING SWITCHING CONTROL SYSTEM (INTERFACE)

BACKGROUND OF THE STUDY

Traditionally, high control in home and office environments takes place through switches (on/off), deals and sliders (dimmers) and sometimes motion sensors. These controls can be incorporated in the built environment such as walls, or attached to lights that peop...

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17. DEVELOPMENT OF REGIONAL FLOW DURATION CURVES FOR SELECTED RIVERS IN UPPER NIGER RIVER BASIN, NIGERIA

ABSTRACT

It is common knowledge that the end user of stream flow data may necessarily not have any prior knowledge of the quality control measures applied in their generation. Thus, this study provides an intuitive attempt to provide an independent quality indicator to boost the confide...

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18. EXPLORING CROSS-LAMINATED TIMBER USE FOR TEMPORARY MILITARY STRUCTURES: BALLISTIC CONSIDERATIONS

ABSTRACT.

The design and construction of temporary military structures, built to house personnel in theater, have changed little since World War II. While lightweight, rapidly deployable, and quick to erect, these gage metal or wood frame structures provide minimal ballistic and blast p...

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