1. A COMPARATIVE STUDY ON HEALTH EDUCATION INTERVENTION ON MALARIA PREVENTION IN COMMUNITIES
EXCERPT FROM THE STUDY
The study concludes that health education intervention has improved the knowledge of the mothers about the various malaria prevention strategies among the nursing mothers with non-significant change in attitude.
Caregivers acted promptly...
2. A STATISTICAL REVIEW OF MALARIA CASES AMONG CHILDREN AND ADULT
Background of the study
The Malaria remains one of the most serious global health problems. There are an estimated one million deaths each year, with nearly seventy five percent (75%) occurring in children living in sub-Saharan Africa. The history of malaria stretc...
3. DESIGN, SYNTHESIS, ANTIMALARIAL EVALUATION AND COMPUTATIONAL STUDIES OF SOME CHALCONE DERIVATIVES
ABSTRACT
Inspired by the previous findings on the structural requirements needed for good antimalarial activity by chalcones against Plasmodium proteases, seventeen chalcone derivatives were designed and synthesized using Claisen-Schmidt condensation of appropriate aldehydes and methyl...
4. ANTIMALARIAL SUSCEPTIBILITY AND DRUG RESISTANCE CHARACTERIZATION STUDIES OF PLASMODIUM SPECIES ISOLATES FROM PATIENTS IN NIGERIA
ABSTRACT
About half of Nigerian population experience at least one episode of malaria per year, resulting in high morbidity and mortality and loss of economic value. Retrospective study of the profile of malarial patients and the antimalarial drugs prescribed at Umaru Musa Yaradua memor...
5. STUDY ON THE EFFICACY AND SAFETY OF ARTEMETHER/LUMEFANTRINE IN THE TREATMENT OF UNCOMPLICATED PLASMODIUM FALCIPARUM MALARIA AMONGST CHILDREN IN NIGERIA
ABSTRACT
Globally, malaria is a major health concern because it causes high morbidity and mortality particularly in children under 5 years because of their low immunity. The development of resistance to chloroquine and sulphodoxine/pyrimethamine in many parts of the world has further wo...
6. EFFECTS OF ANTIMALARIAL DRUGS ON OESTROUS CYCLE AND UTERINE CONTRACTILITY IN RATS
ABSTRACT
Malaria is increasingly a health burden globally with children under the age of 5 and pregnant women being the most vulnerable. Several antimalarials are available in the market today however; the safety data in pregnancy is inadequate especially the first trimester of pregnanc...
7. PHYTOCHEMICAL AND SOME PHARMACOLOGICAL STUDIES OF THE LEAF OF OCHNA RHIZOMATOSA (VAN TIEGH.) KEAY [OCHNACEAE]
ABSTRACT
The extract of the leaf of Ochna rhizomatosa (van Tiegh.) Keay [Ochnaceae], a plant used in the treatment of malaria in Northern Cameroun, was subjected to preliminary phytochemical screening. The result revealed the presence of carbohydrates, steroids, cardiac glycosides, terp...
8. THE EFFECT OF MEFLOQUINE CHEMOPROPHYLAXIS ON THE OUTCOME OF PREGNANCY IN WOMEN OF LOW AND HIGH PARITY IN NIGERIA
ABSTRACT
Malaria accounts for 25% -70% of infant, 30% of under- five and 7% -11% of maternal mortality in Nigeria. The World Health organization recommended malarial drug prophylaxis for pregnant women in malaria endemic areas to prevent the adverse consequences of malaria in pregnancy....
9. EVALUATION OF THE DISSOLUTION AND OTHER CHARACTERISTICS OF CYCLODEXTRIN MOLECULAR INCLUSION COMPLEXES OF ARTEMETHER
ABSTRACT
The present study aimed to improve the dissolution rate, solubility and ultimately, bioavailability of poorly soluble artemether, an antimalarial drug, through inclusion complex formation with hydroxypropyl-β-cyclodextrin. The solid complexes of artemether and hydroxypropy...
10. IN VITROANTIMALARIAL SUSCEPTIBILITY OF PLASMODIUM FALCIPARUM ISOLATES FROM PATIENTS ATTENDING A HEALTH FACILITY IN NIGERIA
ABSTRACT
The continous emergence and spread of resistant strains of Plasmodium falciparumisolates to single and combined antimalarial drug has resulted to increase in mortality rate associated with the disease, especially in the African Continent as a whole and Nigeria in particular whe...
11. PHYTOCHEMICAL AND ANTIMALARIAL STUDIES OF THE LEAVES OF UVARIA CHAMAE P.BEAUV. (ANNONACEAE)
ABSTRACT
Uvaria chamae P.Beauv. belong to the Annonaceae family of flowering plants. It is distributed in the savannah and secondary forest. The plant is used in ethnomedicine for the treatment of malaria, inflammation, gonorrhea, dysentery; pile and fever. The ethyl alcohol leaves extr...
12. PHYTOCHEMICAL AND ANTICONVULSANT STUDIES ON METHANOL EXTRACT OF THE ROOTBARK OFUVARIA CHAMAEP. BEAUV. (ANNONACEAE)
ABSTRACT
Uvariachamae P. Beauv. (Annonaceae) is widely distributed inAfrica, the plant species are used in traditional medicine as an anti-inflamatory, antimalarial, and analgesic. It is also used for treatment of jaundice, epilepsy and microbial infections. The powdered rootbark of U.c...
13. ANTI-PLASMODIAL EFFECTS OF POLYALTHIA LONGIFOLIA (VAR.) LEAF EXTRACTS AGAINST PLASMODIUM BERGHEI IN MICE
ABSTRACT Malaria is one of the most debilitating tropical parasitic diseases and the greatest cause of hospitalization and death. Recurring problems of drug resistance are reinforcing the need for finding new antimalarial drugs. In this respect, natural plant products are the main sources of biol...
14. ANTI-PLASMODIAL, ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES OF ALKALOID FRACTION OF Maytenus senegalensis LEAF IN MICE
ABSTRACT
The treatment inadequacy and toxicity associated with conventional anti-malarial, antiinflammatory and analgesic drugs calls for the search for alternatives from medicinal plants, particularly. In the present study, alkaloid fraction of Maytenus senegalensis leaf was evaluated...
15. EVALUATION OF BIOACTIVE METABOLITE CONTENTS, MOSQUITO LARVICIDAL AND ANTI-PLASMODIAL ACTIVITIES OF EXTRACTS OF THE SPIDER Neoscona adianta
ABSTRACT
In spite of the extensive control efforts, over the years, mosquito still transmit serious human diseases, cause millions of deaths every year and the development of resistance to chemical insecticides resulting in rebounding vectorial capacity. This situation is aggravated wit...
16. IN VIVO EFFICACY OF METHANOLIC EXTRACTS OF ROOT AND LEAF OF Morinda lucida IN Plasmodium berghei - INFECTED MICE
ABSTRACT
Therapeutic effects of the methanolic root extract and a combination of leaf and root extracts of Morinda lucida were evaluated for antiplasmodial activities. The phytochemical screening of the methanolic root extract showed the presence of saponins, flavonoids, alkaloids, phen...
17. ANTIPLASMODIAL ACTIVITY OF AQUEOUS AND ETHANOLIC EXTRACTS OF ANACARDIUM OCCIDENTALE AND CYMBOPOGON CITRATUS
ABSTRACT
The search for antimalarial compounds was necessitated by Plasmodium falciparum resistance to most antimalarial drugs. In endemic countries where malaria is prevalent, medicinal plants are often used to treat malaria. In this study, the in vitro antimalarial activities of crude...
