1. AN ANTIMICROBIAL ANALYSIS AND PHYTOCHEMICAL OF Mangifera indica AND Carica papaya LEAVES
BACKGORUND TO THE STUDY
It is well known that in order for a plant to protect itself, it creates certain compounds that can also protect humans from sickness. Today, there are approximately 4000 distinct phytochemicals that have the potential to alter disorders such as...
2. ASSESSMENT ON THE ROLE OF PLANTS IN THE TREATMENT OF DISEASES CAUSED BY MICRO-ORGANISMS BASED IN THE NATURAL PRODUCTS
BACKGROUNG OF STUDY
Infectious diseases are a significant cause of morbidity and mortality worldwide, accounting for approximately 50% of all deaths in tropical countries and as much as 20% of deaths in the Americas. Despite the significant progress made in microb...
3. ANALGESIC AND ANTI-INFLAMMATORY EFFECTS OF METHANOL EXTRACT AND FRACTIONS OF LAGGERA AURITA LINN F (COMPOSITAE) IN MICE AND RATS
ABSTRACT
The plant Laggera aurita is an annual or biennial herb of widespread in dry waste places from across Senegal to Southern Nigeria. The plant has been reportedly used for medicinal purposes including treatment of rheumatic pain, healing of cuts and bruises, and as a last resort t...
4. ANALGESIC AND ANTI-INFLAMMATORY STUDIES ON METHANOL ROOT EXTRACT OF ANDROPOGON GAYANUS KUNTH (POACEAE) IN MICE AND RATS
ABSTRACT
The plant Andropogon gayanus is employed in herbal medicine for the treatment of various disease conditions. The dried root of the plant is soaked in milk and taken for the treatment of postpartum pain and bronchitis in North-west Nigeria. In this study the methanol root extrac...
5. ANALGESIC, ANTI-INFLAMMATORY AND OTHER PHARMACOLOGICAL ACTIVITIES OF METHANOL LEAF EXTRACT OF OLAX SUBSCORPIOIDEA OLIV (OLACACEAE) IN LABORATORY ANIMALS
ABSTRACT
Synthetic analgesic and anti-inflammatory drugs have major side effects such as constipation, nausea and vomiting, sedation and mental clouding, etc.,which have significantly limited their use.There is therefore, an intensification of search for newer analgesic and anti-inflamm...
6. ANALGESIC, ANTI-INFLAMMATORY AND TOXICITY STUDIES ON METHANOLIC LEAF EXTRACT OF ROTHMANNIA LONGIFLORA SALISB (RUBIACEAE) IN RATS AND MICE
ABSTRACT
The herbalists in several African Countries have used Rothmannia longiflora decoctions as febrifugal and analgesic agent. The present study examined the analgesic, anti-inflammatory and toxicological profile of the methanolic extract of the plant in experimental animals. The pr...
7. CHEMICAL AND BIOLOGICAL STUDIES OF HONEY BEE PROPOLIS COLLECTED FROM ZANGO KATAF LOCAL GOVERNMENT AREA OF KADUNA STATE, NIGERIA
ABSTRACT
Honeybee Propolis from Apis mellifera (Linn), has been used in ethno medicine as an emollient in the treatment of ringworm, measles, chickenpox and with reported biological activities, such as antitumor, antioxidant, immunomodulatory action and anti-inflammatory action among ot...
8. ANTIMICROBIAL PROPERTY OF THE HEXANE EXTRACT FROM THE PODS OF ACACIA NILOTICA (L.) DEL. (MIMOSACEAE)
ABSTRACT
Acacia niloticais a multipurpose plant belonging to the family Mimosaceae. Commonly known as Prickly acacia in English and Bagaruwa in Hausa, It has medicinal properties which include antimalaria, antimicrobial, anti-inflammatory, anticancer, etc. Traditionally, the pods are us...
9. COMPARATIVE PHARMACOGNOSTIC AND BIOLOGICAL STUDIES ON THE LEAVES OF VERNONIA AMYGDALINA DEL. AND VERNONIA KOTSCHYANA SCH. BIP. (ASTERACEAE)
ABSTRACT
Vernonia amygdalina Del. and V. kotschyana Sch. Bip. (Asteraceae) are respectively shrub or tree and annual herb found commonly in tropical and subtropical countries. They are employed in ethno-medicine in the treatment of many ailments namely stomach ache, gingivitis, rheumati...
10. PHARMACOGNOSTIC, ANALGESIC AND ANTI-INFLAMMATORY STUDIES ON THE LEAVES OF MICROTRICHIA PEROTITII DC (ASTERACEAE)
ABSTRACT
Microtrichia perotitii DC Asteraceae (Compositeae) is an herb found in the tropical countries. Ethno-medicinally, it is mainly used for the treatment of pain related diseases such as toothaches, cuts and burns and few ailments like rashes, rheumatism, jaundice, stomachaches and...
11. PHYTOCHEMICAL AND ANTI-INFLAMMATORY STUDIES OF N-BUTANOL SOLUBLE FRACTION OF THE METHANOLIC EXTRACT OF THE AERIAL PARTS OF INDIGOFERA HIRSUTA LINN (LEGUMINOSAE)
Abstract
Indigofera hirsuta Linn. (Leguminosae) is a well-known plant used in African traditional medicine as an anti-inflammatory, antibacterial, antiulcer, anti-venom and anticonvulsant. The air-dried aerial parts of I. hirsuta was extracted with methanol using a soxhlet extractor and...
12. PHYTOCHEMICAL AND BIOLOGICAL STUDIES OF ETHANOL EXTRACT OF CHROZOPHORA SENEGALENSIS (LAM) A. JUS
Abstract
The ethanol extract of root of Chrozophora senegalensis use in ethanomedicine to treat diarrhea, rheumatism, taeniasis, stomach ache, inflammation and veneral diseases was subjected to Phytochemical and Biological studies. Phytochemical analysis was carried out using standard p...
13. PHYTOCHEMICAL AND SOME BIOLOGICAL STUDIES OF THE METHANOL EXTRACT OF THE AERIAL PARTS OF AMPELOCISSUS GRANTII(BAKER) PLANCH. (VITACEAE)
ABSTRACT
The plant Ampelocissus grantii is used in traditional medicinal practice in the treatment of cough, wounds, venereal infections and other ailments.Phytochemical examination of the methanol extract of the aerial parts of Ampelocissus grantii (Baker) Planch (Family, Vitaceae) rev...
14. PHYTOCHEMICAL AND SOME PHARMACOLOGICAL STUDIES ON THE LEAF EXTRACT OF ZIZIPHUS MUCRONATA WILLD. (RHAMNACEAE)
ABSTRACT
Chronic inflammation has been implicated in most non-communicable/chronic degenerative diseases including age-related cancers. Ziziphus mucronata, a plant used in ethnomedicine to treat different painful and inflammatory conditions, was subjected to phytochemical investigation...
15. SOLID DISPERSION AS AN APPROACH FOR SOLUBILITY AND DISSOLUTION ENHANCEMENT OF IBUPROFEN AND PIROXICAM
ABSTRACT
The aim of this study was to enhance the solubility and hence dissolution rate of two poorly soluble drugs: ibuprofen and piroxicam using Eudragit RS 100 and hydroxymethylpropylcellulose (HPMC) as carriers, by solid dispersion technique and to evaluate the effect of trona (sodi...
16. SOME PHARMACOLOGICAL STUDIES ON THE ETHANOLIC STEM BARK EXTRACT OF PTEROCARPUS ERINACEUS POIR (FABACEAE)
ABSTRACT
Some pharmacological effects of the 70% ethanolic stem bark extract of Pterocarpus erinaceus were investigated in experimental animals. Preliminary Phytochemical studies of the ethanolic extract revealed the presence of Tannins, Carbohydrates, Proteins & Amino acids, Flavon...
17. TOXICOLOGICAL, ANTIPYRETIC, ANALGESIC AND ANTI-INFLAMMATORY PROPERTIES OF METHANOL LEAF EXTRACT OF DALBERGIA SAXATILIS HOOK. F (FABACEAE) IN RATS AND MICE
ABSTRACT
The decoction of the leaves of Dalbegia saxatilis is used in Traditional Medicine for various ailments such as cough, small pox, skin lesions, bronchial ailments and toothache. The study was aimed at establishing a safety profile, evaluating phytochemical constituents and some...
18. PHARMACOLOGICAL AND TOXICOLOGICAL STUDIES OF THE METHANOL EXTRACT OF ACACIA ATAXACANTHA LEAF D.C. (LEGUMINOSAE) IN MICE AND RATS
ABSTRACT
Acacia ataxacantha is used in traditional medicine for management of pain and inflammation. Literature survey revealed that the safety and efficacy of such uses have not been scientifically validated. The present study was designed to study the pharmacological and toxicological...
19. EFFECT OF AQUEOUS ETHANOL LEAF EXTRACT OF COMBRETUM MICRANTHUM G. DON (COMBRETACEAE) ON SOME INDUCED SYSTEMIC INFLAMMATORY IMMUNE RESPONSE SYNDROMES IN MICE AND RATS
Abstract
The cellular immunity is often suppressed by infection, disease conditions and drug medication that are in continous association with mankind. Combretum micranthum is a plant known for its antioxidant, antimicrobial, anti-inflammatory and various other properties of immune boos...
20. PHARMACOGNOSTIC AND ANTI-INFLAMMATORY STUDIES OF THE LEAVES OF ALLOPHYLUS AFRICANUS BEAUV (SAPINDACEAE)
ABSTRACT
This study evaluated some pharmacognostic standards and anti-inflammatory activity of the leaves of Allophylus africanus Beauv (Sapindaceae). The plant has a wide distribution in West Africa, with Nigeria (Mambila Plateau, Calabar) inclusive. It has been used in communities for...
21. PHARMACOGNOSTIC AND ANTI-INFLAMMATORY STUDIES ON THE LEAF OF LUDWIGIA ABYSSINICA RICH. (ONAGRACEAE)
ABSTRACT
Ludwigia abyssinica Rich (Onagraceae) is a plant native to South America but now widely distributed in Africa. It has been exploited for its medicinal and economic importance. It is traditionally used for the treatment of a number of ailments such as cough, skin diseases, sores...
22. PHARMACOGNOSTIC AND BIOLOGICAL EVALUATON OF THE ROOT BARK OF SABA COMORENSIS (BOJ.) PICHON (APOCYNACEAE)
ABSTRACT
Saba comorensis (Boj) Pichon (Apocynaceae) has been used traditionally in various parts of Tropical Africa region as an aphrodisiac, for rheumatism, arthritis, liver disease, jaundice, venereal disease, normal spleen function, as laxative, and purgative. This study is aimed at...
23. PHYTOCHEMICAL AND ANTI-INFLAMMATORY STUDIES ON THE HEXANE EXTRACT OF THE STEM BARK OF STEGANOTAENIA ARALIACEAHOSCHTS (APIACEAE)
ABSTRACT
Inflammation has been implicated in virtually all human and animal diseases. It has become the focus of global scientific research, more so, since the currently used anti-inflammatory agents both steroidal and non-steroidal are prone to evoking serious adverse reactions. Stegan...
24. EVALUATION OF AQUEOUS AND METHANOL ROOT EXTRACTS OF CALOTROPIS PROCERA AIT (ASCLEPIADACEAE) FOR ANTI-ASTHMATIC ACTIVITY ON WISTAR RATS AND GUINEA PIG ILEUM
ABSTRACT
Asthma, which affects an estimated 300 million people worldwide, is an incurable health disorder of a major public health concern globally. The present orthodox therapy for asthma has several drawbacks including many undesirable side effects and high cost of management (especia...
25. ANTI-PLASMODIAL, ANTI-INFLAMMATORY AND ANALGESIC ACTIVITIES OF ALKALOID FRACTION OF Maytenus senegalensis LEAF IN MICE
ABSTRACT
The treatment inadequacy and toxicity associated with conventional anti-malarial, antiinflammatory and analgesic drugs calls for the search for alternatives from medicinal plants, particularly. In the present study, alkaloid fraction of Maytenus senegalensis leaf was evaluated...
26. PHYTOCHEMICAL ANALYSIS AND THE ANTIINFLAMMATORY ACTIVITIES OF METHANOL EXTRACT OF CRATEVA ADANSONII
ABSTRACT
Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants. The urgency generated by in increased rate of stroke, atheroselerosis attributed to prolong use of cyclooxygenase-1 and 2 inhibitors have acceralated...
27. PHYTOCHEMICAL AND ANTI-INFLAMMATORY PROPERTIES OF METHANOL EXTRACT OF CRATEVA ADANSONII STEM BARK.
ABSTRACT
78 This research investigated the phytochemical and anti-inflammatory properties of methanol extract of Crateva adansonii stem bark. Although several edible and non-edible plants parts are used in inflammatory treatment, many record has been found of the use of Crateva ad...
28. THE ANTI-INFLAMMATORY ACTIVITY OF Crateva adansonii DICHLOROMETHANE FRACTION.
ABSTRACT
Crateva adansonii is a medicinal herb commonly used in parts of Africa because of the side effects of Non-Steroidal Anti-inflammatory Drugs (NSAID), like heart diseases and kidney failure. Inflammation is a major public heart issue in the world but treatment is becoming complex...
29. ETHNOPHARMACOLOGICAL AND PHYTOCHEMICAL PROPERTIES OF SOME PLANTS USED IN THE MANAGEMENT OF PAIN
ABSTRACT
Pain is a worldwide problem and is associated with most disease conditions. The properties of herbs used to treat pain were investigated with the aim of confirming their use and finding out some pharmacological properties that may augment their analgesic activity. A total of ei...
30. ANTIPLASMODIAL ACTIVITY OF AQUEOUS AND ETHANOLIC EXTRACTS OF ANACARDIUM OCCIDENTALE AND CYMBOPOGON CITRATUS
ABSTRACT
The search for antimalarial compounds was necessitated by Plasmodium falciparum resistance to most antimalarial drugs. In endemic countries where malaria is prevalent, medicinal plants are often used to treat malaria. In this study, the in vitro antimalarial activities of crude...
31. ANALGESIC, ANTI-INFLAMMATORY AND ANTI-CONVULSANT ACTIVITIES OF STEM BARKEXTRACT OF Erythrophleumivorense(A Chev) IN RATS AND MICE
ABSTRACT
Erythrophleumivorense isused in traditional medicine for the treatment of convulsion, swellings, body pain and as emetic agents. There is a dearth of scientific information in support of the traditional claims. This study was therefore designed to investigate the analgesic, ant...
32. THE EFFECT OF IONIZING RADIATION ON THE HIPPOCAMPUS OF THE BRAIN
CHAPTER ONE
INTRODUCTION
1.1 Background of the study
The hippocampus, a region situated within the medial temporal...
