STATEMENT OF PROBLEM
Due to increase in development of resistance of microorganisms to antimicrobial drugs in recent time, search for plants with antimicrobial activity have gained increasing importance. Globally, the last two decades have witnessed an unprecedented increase of drug resistance by pathogenic organisms as well as the appearance of undesirable side effect of certain antibiotics (Akunyili et al., 1991; Anegbeh et al., 2006). Other limitations of modern chemotherapeutic drugs are their high cost and non-availability especially in the rural area.The research into the discovery of new potent drugs from plant is based on the use of plant bio principle from extracts and essential oil to treat infections or diseases caused by pathogenic organisms (Elaezu et al., 2012). Current Stains in use in our laboratories are chemically synthesized besides being expensive they are hazardous to human health as some dye components are carcinogenic. 6 Others have strong allergy resulting in their withdrawal as their hazards become recognised (Avwioro et al., 2005).
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