EVALUATION OF MOLLUSCICIDAL ACTIVITIES OF CRUDE AND ALKALOIDAL FRACTION OF ANOGEISSUS LEIOCARPUS (AFRICAN BITCH) AND PSEUDOCEDRELA KOTSCHYI (DRY ZONE CEDAR) ON VECTOR OF SCHISTOSOMIASIS
- Project Research
- 1-5 Chapters
- Abstract : Available
- Table of Content: Available
- Reference Style: APA
- Recommended for : Student Researchers
- NGN 3000
ABSTRACT
Over the years, the use of plant-based molluscicides has received substantial consideration in the satisfaction for cost-effective alternatives to chemotherapy and synthetic molluscicides in schistosomiasis control. This study was aimed at evaluating the molluscicidal potentials of crude and Alkaloidal fractions of Anogeissus leiocarpus and Pseudocedrela kostchyi against vector of schistosomiasis. Both aqueous and methanol crude extracts of the plants were tested for the presence of bioactive metabolites. Ten snails each was exposed to different concentrations (10 mg/L, 20 mg/L, 40 mg/L, 80 mg/L, 160 mg/L, 200 mg/L and 300 mg/L) of aqueous, methanol and alkaloid extracts of Anogeissus leiocarpus and Pseudocedrela kostchyi for the interval of 40 minutes, 24 hours and 72 hours respectively. Fifty other snails were also exposed to 200 mL of distilled water for 24 hours as control. The results indicated the presence of phytochemicals such as flavonoid, Tannis, Saponins, Alkaloids and terpenoids in both aqueous and methanol extract of both plants. Steroid was only present in methanol extract. Cardia glycoside was absent in aqueous extract of the extracts. The results showed dose dependent activities with highest dose having a significant (P<0.05) highest snail mortality. The two plants extracts showed appreciable molluscicidal efficacies against the two exposed snail species with LC50 of 157.29, 88.56, and 240.03mg/L for aqueous, methanol and Alkaloidal fraction of A. leiocarpus against B. pfeifferi and LC50 of 128.73, 78.07 and 344.02mg/L for P. koschyi respectively. There was a significant decrease in the level of Alamine transaminase (ALT) and Aspartate triaminase (AST) in the tissue of the exposed snail compared to the control. Based on the findings of this study, there is need to examine the Histoachitecture of the exposed snail in other to ascertain the observed mechanism of action found in the alteration of the tissue enzymes
Related Project Materials
ASSESSMENT OF THE IMPACT OF GOVERNMENTAL ACCOUNTING FOR DISASTER RECOVERY FUNDS
ABSTRACT: ASSESSMENT OF THE IMPACT OF GOVERNMENTAL ACCOUNTING FOR DISASTER RECOVERY FUNDS
This study assesses the impact of governmental...
THE IMPACT OF ACCESSIBILITY ON RESIDENTIAL PROPERTY VALUES IN NEW HAVEN ENUGU
-
-
BACKGROUND OF THE STUDY
-
At the foot of the Milliken Hill r...
ANALYSIS OF CREDIT FACILITIES TO SMALL SCALE FARMERS (A STUDY OF SMALL-SCALE FARMERS IN BENDE LOCAL GOVERNMENT AREA OF ABIA SATE)
ABSTRACT
Inadequate support in terms of credit facilities from government and financial institution has been identified as one of the maj...
ADVANCES IN SEARCH ENGINE TECHNOLOGY AND THEIR IMPACTS ON LIBRARIES
ABSTRACT
Libraries see themselves as central information providers for their clientele, at universities or research inst...
CARGO FREIGHT RATE IN LINER SHIPPING AND IT'S CORRELATION TO HIGH PRICES OF IMPORTED GOODS IN NIGERIA
ABSTRACT
The research is organized into five chapters. The objective of research is to assess the impa...
EFFECT OF PUBLISHED FINANCIAL STATEMENT ON SHAREHOLDER INVESTMENT DECISION
STATEMENT OF THE PROBLEM
Virtually, every economic entity maintains its records on a historical cost basis. The historic...
THE ROLE OF ACCOUNTANT IN THE ECONOMIC DEVELOPMENT OF NIGERIA
BACKGROUND OF THE STUDY
The concept of Economic Development has to do with innovation and improvement in people's qu...
THE EFFECTIVENESS OF COMPETENCY-BASED ASSESSMENT IN TECHNICAL SCHOOLS
ABSTRACT: This study evaluates the effectiveness of competency-based assessment in technical schools, examining its role in aligning education...
SURVEY OF DIFFERENT SOURCES OF INCOME FOR DEVELOPMENT OF SECONDARY SCHOOLS
ABSTRACT
This study investigated the different sources of income for development of secondary scho...
VALUE ADDITION AS A BASIS FOR ENHANCING PRODUCTIVITY IN RICE PRODUCTION AND PROCESSING
Abstract
This study is on value addition as a basis for enhancing productivity in rice production and processing....
