Abstract
Present investigations were carried out on the effect of ethanol extract of Desmodium velutinum stem on some liver enzymes of albino wistar rats fed with 8 high fat from cow‟s brain. Twelve healthy albino wistar rats were divided into four groups. Group I rats were fed with balanced diet (normal feed, that is grower‟s mash) and tap water. Group II rats were fed with fat diet (cow‟s brain) (3.6g/day) alone. Group III rats received combined mixture of 70% fat diet (cow‟s brain) with 30% ethanol extract of Desmoduim elutinum stem (2.7g/day), Group IV rats were fed with fat diet (cow‟s brain) and were administered with a drug atorvastatin (5mg/rat/day). The rats were sacrificed at the end of the experimental (two weeks) period. The plant extract was screened for its phytochemical constituents, using standard procedures. Phytochemical screening revealed the presence of tannins, flavonoids, saponins and alkaloids. The liver function tests was assessed by measuring the total bilirubin, total serum protein, direct and indirect bilirubin and liver enzymes such as Alanine amino transferase (ALT), Aspartate amino transferase (AST), Alkaline phosphate (ALP), Gamma-glutamyl transferase (GGT) on the liver of the albino wistar rat. The serum, ALT, ALP, AST and bilirubin concentration of the albino wistar rat increased significantly (P>0.05) compared to their total protein concentration. The result obtained indicate that the ethanol extract of Desmodium Velutinum stem possess hepatoprotective activity on the fatty liver of albino wistar rat fed with fat from cow‟s brain. The studied plant showed variable amount of phytochemicals including flavonoid, alkaloid, saponin, tannins, terpenoid which were determined quantitatively using literature methods. The significant effect of the Desmodium velutinum stem ethanol extract was compared with standard drug, atorvastatin. The result in the present study suggest that the ethanol extract of Desmodium velutinum stem can be used in treating liver diseases.
ABSTRACT: This research explored the impact of early childhood education on nutrition education among young children. The objectives were to evalua...
Abstract
The study examined the influence of parents’ occupation and education on the career choice...
BACKGROUND OF THE STUDY
Advertising has been defined as “a powerful communication force and a vital marketing tool...
Introduction
Co-operative Economics and Management in tertiary institutions help to improve the co-oper...
ABSTRACT
This study was carried out to examine the effect of job design on secretaries performance a case study of Ethio...
Background of the study
Chronic diseases represent a significant public health challenge worldwide, imp...
Abstract
This research examined the effect of social media on consumer buying behaviour of Jumia Nigeria in Calabar metr...
ABSTRACT
This project research work attempts to explore the relevance of Accounting Information and its role in the mana...
Abstract
Is there any hope for genuine democratic practice in Nigeria? This study was designed to examine the roles of e...
ABSTRACT: This research investigates the role of early childhood education in reducing malnutrition among young children. Educating children a...