0704-883-0675     |      dataprojectng@gmail.com

THE EFFECT OF ETHANOL EXTRACT OF DESMODIUM VELUTINUM STEM ON SOME MARKER EMZYME IN LIVER OF ALBINO WISTAR RATS

  • Project Research
  • 1-5 Chapters
  • Abstract : Available
  • Table of Content: Available
  • Reference Style: APA
  • Recommended for : Student Researchers
  • NGN 3000

Abstract

Present investigations were carried out on the effect of ethanol extract of Desmodium velutinum stem on some liver enzymes of albino wistar rats fed with 8 high fat from cow‟s brain. Twelve healthy albino wistar rats were divided into four groups. Group I rats were fed with balanced diet (normal feed, that is grower‟s mash) and tap water. Group II rats were fed with fat diet (cow‟s brain) (3.6g/day) alone. Group III rats received combined mixture of 70% fat diet (cow‟s brain) with 30% ethanol extract of Desmoduim elutinum stem (2.7g/day), Group IV rats were fed with fat diet (cow‟s brain) and were administered with a drug atorvastatin (5mg/rat/day). The rats were sacrificed at the end of the experimental (two weeks) period. The plant extract was screened for its phytochemical constituents, using standard procedures. Phytochemical screening revealed the presence of tannins, flavonoids, saponins and alkaloids. The liver function tests was assessed by measuring the total bilirubin, total serum protein, direct and indirect bilirubin and liver enzymes such as Alanine amino transferase (ALT), Aspartate amino transferase (AST), Alkaline phosphate (ALP), Gamma-glutamyl transferase (GGT) on the liver of the albino wistar rat. The serum, ALT, ALP, AST and bilirubin concentration of the albino wistar rat increased significantly (P>0.05) compared to their total protein concentration. The result obtained indicate that the ethanol extract of Desmodium Velutinum stem possess hepatoprotective activity on the fatty liver of albino wistar rat fed with fat from cow‟s brain. The studied plant showed variable amount of phytochemicals including flavonoid, alkaloid, saponin, tannins, terpenoid which were determined quantitatively using literature methods. The significant effect of the Desmodium velutinum stem ethanol extract was compared with standard drug, atorvastatin. The result in the present study suggest that the ethanol extract of Desmodium velutinum stem can be used in treating liver diseases.




FIND OTHER RELATED TOPICS


Related Project Materials

THE IMPACT OF TECHNOLOGY ON INTERNATIONAL ACCOUNTING PRACTICES

 THE IMPACT OF TECHNOLOGY ON INTERNATIONAL ACCOUNTING PRACTICES

ABSTRACT

This research aims to investigate (1) the influen...

Read more
ASSESSMENT OF THE UNITED NATIONS DEVELOPMENT PROGRAMME (UNDP) ASSISTANCE ON PROMOTION OF DEMOCRATIC NORM IN NIGERIA, 2003 -2015

ABSTRACT

This study evaluates United Nations Development Programme assistance for the promotion of democratic norm in Nigeria (2003 to 20...

Read more
ASSESSMENT OF THE PROVISION AND RESOURCES UTILIZATION FOR THE IMPLEMENTATION OF OFFICE TECHNOLOGY AND MANAGEMENT CURRICULUM IN POLYTECHNICS IN SOUTH-SOUTH NIGERIA

Background to the Study

To a large extent, the success or failure of any educational system depends on the successful p...

Read more
impact of intergrated marketing communication(inc)

Abstract

This study was informed by the necessity of research in the impact of integrated marketing communication on brand building. A st...

Read more
EFFECTS OF MOTIVATION ON SALESFORCE PERFORMANCE IN GUINNESS NIGERIA PLC AND MOBILE TELECOMMUNICATION NETWORK

Abstract

This study was conducted to evaluate the effects of motivation on sales force performance in Guinness Nigeria P...

Read more
PERCEPTION OF PARENTS ON OVER-SCHOOLING OF CHILDREN AT THE PRE-PRIMARY EDUCATION IN ONITSHA EDUCATIONAL ZONE OF ANAMBRA STATE

ABSTRACT

Over-schooling at the pre-primary school is a serious violation of the provisions of National Policy on Educati...

Read more
INFLUENCE OF SUPERVISION ON TEACHERS EFFECTIVENESS AMONG PRIVATE SCHOOLS

ABSTRACT

The focus of this research was to look at the relationship between supervision and teachers effectiveness in so...

Read more
THE EFFECTS OF PUBLIC RELATIONS ON ORGANIZATION: CASE STUDY OF ZENITH BANKS IN ANAMBRA STATE

Background of the study

Public Relation is the art and social science of analyzing trends predicting th...

Read more
THE PROSPECTS AND CHALLENGES OF FIDUCIARY ACCOUNTING FOR NON-TRADITIONAL ASSETS

THE PROSPECTS AND CHALLENGES OF FIDUCIARY ACCOUNTING FOR NON-TRADITIONAL ASSETS

Abstract: Fiduciary accounting for non-traditional assets...

Read more
DEVELOPMENT OF MODELS FOR RATING SEISMIC ACTIVITIES USING RADIATED ENERGY OF EARTHQUAKES

Earthquakes

An earthquake is the result of a sudden release of energy in the Earth's crust that creates seismic wave...

Read more
Share this page with your friends




whatsapp