PHARMACOGNOSTIC AND ANTIULCER STUDIES ON THE LEAF OF LEUCAS MARTINICENSIS (JACQ) R.Br. (LAMIACEAE)
- Project Research
- 1-5 Chapters
- Abstract : Available
- Table of Content: Available
- Reference Style: APA
- Recommended for : Student Researchers
- NGN 3000
ABSTRACT
Leucas martinicensis is an annual herb which is used for repellant of mosquito. It has minty odor. It is an erect plant which is usually unbranched, with length of up to 1m, which is finely hairy. The plant are widely used in Northern part of Nigeria and it has been exploited for both its medicinal and economic properties with no scientific justification about its antiulcer activities. It is traditionally used for the management of a number of ailments including the treatment of diarrhea, skin rashes, epilepsy, gastroenteritis, cholera, relieving pain during pregnancy and as anti-malaria. The pharmacognostic studies and antiulcer activities of the leaves of Leucas martinicensis (Lamiaceae) was carried out to validate the ethno medicinal claimed of the leaves in treating ulcer. Evaluation of the fresh, powdered leaves and phytochemicals screening were carried out. The acute toxicity and antiulcer properties revealed the leaves potential as source of drug for further utilizations. The microscopical characters and physical constants of the leaf were determined, which revealed the presence of some prominent features like multicellular covering trichomes and diacytic stomata. The physical constants evaluated showed moisture content 8.9% of Leucas martinicensis, total ash value of 6.8 %, water soluble ash of 6.0 %, acid insoluble ash of 3.5 %, ethanol extractive value of 16.0 % and water extractive value of 20.3 %. Phytochemical analysis of the leaves extracts revealed the presence of alkaloids, tannins, flavonoids, carbohydrate, cardiac glycosides, saponins, triterpenes and steroids and anthracenes. The median lethal dose (LD50) of the extract was found to be greater than 3000 mg/kg when administered orally in rats and considered practically non-toxic. The extract demonstrated protective activity against ethanol induced gastric ulcer lesions in albino rats. This is evidenced in the significant and increased preventive index with doses (300, 600 and 900 mg/kg) of the extract. The methanol extract was observed to have the best activity compared to organic solvent ix fractions. The results provided some pharmacognostic standards for proper identification of the plant and scientific basis for the traditional use of the leaf in the treatment of ulcer.
Related Project Materials
THE ROLE OF ACCOUNTING INFORMATION IN PRODUCTION DECISION MAKING
ABSTRACT
Managers make decision in order to choose from alternative course of action at a dynamic rate. This is done in...
HOME ECONOMICS STUDIES AND ITS IMPACT IN HIGHER INSTITUTIONS OF LEARNING
EXCERPT FROM THE STUDY
Over the years there have been series of challenges faced by most teachers in teaching home econo...
AN INVESTIGATION INTO THE INFORMATION AVENUE AND THE USE OF TRADITIONAL MEDICINE AMONG FARMERS
ABSTRACT
The study examined the the information avenue and the use of traditional medicine among farmers in Edo and Delt...
A CRITICAL SURVEYOR OF ADVERTISING AS A DETERMINANT OF CUSTOMER PATRONAGE IN THE FAST FOOD INDUSTRY
ABSTRACT
This research study is generally intended to critically survey advertising as a determina...
A CRITICAL EXAMINATION OF VIOLENT FILM AND ITS EFFECTS ON NIGERIA FEMALE CHILDREN
EXCERPT FROM THE STUDY
The goal of this study was to examine the effect of violent film on Nigerian female children in O...
INFLUENCE OF VISUAL AIDS ON EFFECTIVE TEACHING AND LEARNING OF SOCIAL STUDIES
ABSTRACT
This research work is designed to investigate “The influence of visual aids on effective teaching and lea...
NIGERIA’S NATIONAL HEALTH INSURANCE SCHEME: Prospects and Challenges
Background Of Study
Since 1981, when the Nigerian Medical Association conducted a meeting in Calabar a...
Characters and Voices- The Bildungsroman Tradition in Selected Third Generation Nigerian Novels
Background to the Study
Early twenty-first century witnessed the emergence of new voices in Nigerian literature, especially, the novel ge...
THEISM AND THE PROBLEM OF EVIL: A CRITICAL STUDY
ABSTRACT
The presence of evil in a world said to be created by a “Being” who is not only omnipotent, omnisc...
ASSESSING URBANIZATION AND ITS IMPACT ON ENVIRONMENTAL HEALTH QUALITY IN NIGERIA
ABSTRACT
Urbanization refers to general increase in population and the amount of industrialization of a settlement...
