EVALUATION OF TABLETING PROPERTIES OF CRUDE TURMERIC (CURCUMA LONGA LINN) POWDER
- Project Research
- 1-5 Chapters
- Abstract : Available
- Table of Content: Available
- Reference Style: APA
- Recommended for : Student Researchers
- NGN 3000
ABSTRACT
The aim of this work is to formulate crude turmeric powder into tablet form. The powder was produced from the turmeric rhizome. Physicochemical properties of the powder; angle of repose (AR), bulk density (BD), tapped density (TD), Hausner‟s ratio (HR), Carr‟s index (CI), true density, moisture content, and flow rate (FR) were evaluated. The particles size and morphology were determined using Scanning electron microscope and sieve analysis. The tablets were formulated using both wet granulation and direct compression methods. The wet granulation was carried out using microcrystalline cellulose (MCC) as diluent and gelatin (GLT) as binder and compared with maize starch (MS), polyvinylpyrrolidone (PVP), and Acacia (AC) as binders. Direct compression method was carried out using Avicel PH101 and Ludipress. Compaction studies were also conducted on the powder. The powder particles were found to be rough, elongated and flaky shaped, with poor flow based on AR (40.3⁰), HR (1.736), CI (42.4 %) and FR (1.4 g/s) and the particles are also interlocked. The granules exhibited marked improvement in flowability: AR (31.14 ° - 34.79 °), HR (1.21-1.29), CI (17.14 – 37.00), FR (1.44 – 2.81 g/s) and moisture content (10.50 – 13.50 %). The powder deformed by fragmentation and is brittle in nature. The granules have improved plastic deformation explained by both Heckel and Kawakita equations. Turmeric tablets with good mechanical properties were produced by both wet granulation and direct compression methods. Gelatin binder produced good tablets at 2.5 % concentrations and above. Using wet granulation method, MS at 5 % binder concentration produced best tablets in terms of mechanical strength (CSFR: 8.667 compared with gelatin‟s 7.547) but 5 % gelatin binder gave best release tablets (97.70 % at 45 min). Avicel PH101 and Ludipress produced good tablets both at 50 – 60 % dilutions. Avicel viii PH101 produced best quality tablets in terms of mechanical strength (CSFR/DT: 6.1460 compared with Ludipress: 2.587) and release profile (86.19 % at 45 min). Turmeric powder can best be formulated into tablet by wet granulation method using gelatin as a binder while Avicel PH101 produced best tablets by direct compression method.
Related Project Materials
POLITICAL LEADERSHIP AND UNDERDEVELOPMENT IN NIGERIA. (A STUDY OF BABANGIDA’S ADMINISTRATION) A RESEARCH PROJECT PRESENTED TO THE DEPARTMENT OF PUBLIC ADMINISTRATION, SCHOOL OF BUSINESS, FEDERAL POLYTECHNIC OKO.
ABSTRACT
A CURSORY GLANCE AT THE ECONOMIC CONDITIONS OF NIGERIA WILL REVEAL THAT UNDERDEVELOPMENT HAS PERSISTED IN SPITE...
MICROFINANCE BANK AND ITS IMPACT ON SMALL AND MEDIUM ENTERPRISES IN NIGERIA
EXCERPT FROM THE STUDY
The idea of creating Micro Finance Institutions (MFIs) is to provide an easy accessibility of SME...
THE EFFECT OF PARENTAL INFLUENCE OF THE CHOICE OF CAREER AMONG SECONDARY SCHOOL
-
-
Background of the study
-
Career play a very fundamental and...
THE ROLE OF RADIO ON RURAL DEVELOPMENT: A STUDY OF NASARAWA BROADCASTING STATION LAFIA
ABSTRACT
This study was carried out on the role of Radio on rural development: A study of nasarawa...
RELATIONSHIP BETWEEN SCHOOL FACILITIES AND STUDENTS PERFORMANCE IN PUBLIC SECONDARY SCHOOLS
Abstract
The study attempted to investigate the relationship between school facilities and students performance in selec...
A PHONOLOGICAL ANALYSIS OF THE SOUND SYSTEM OF JABA LANGUAGE
Background to the Study
This study focuses on de...
CARDIO PROTECTIVE ACTIVITIES OF N-HEXANE EXTRACT OF DESMODIUM VELUTINUM STEM ON ALBINO WISTER RAT
ABTRACT
This study evaluates the cardio protactive effect of N-hexane extract of Desmodium Velutinum stem on albino wister rat. Rats used...
A DECENTRALIZED APPLICATION OF DYNAMIC PROGRAMMING TO COMMUNICATION NETWORK RECONFIGURATION
ABSTRACT
A decentralized framework for network optimization is presented for wireless sensing nodes. The wireless sensing nodes use a dyn...
EMPLOYMENT OPPORTUNITIES FOR GRADUATE OF OFFICE TECHNOLOGY AND MANAGEMENT
ABSTRACT
The purpose of this study is to survey the Employment Opportunities for Graduate of Office Tec...
RELATIONSHIP AMONG ACADEMIC STRESS, MOTIVATION AND ACADEMIC ACHIEVEMENT OF NCE STUDENTS OF FCT COLLEGE OF EDUCATION, ZUBA, NIGERIA
ABSTRACT
This study investigated the relationship among academic stress, motivation and academic achievement of NCE students of FCT Colle...
