COMPARATIVE EVALUATION OF THE ASCORBIC ACID CONTENT OF MINERAL ASCORBATE AND ASCORBIC ACID TABLETS MARKETED IN ZARIA
- Project Research
- 1-5 Chapters
- Abstract : Available
- Table of Content: Available
- Reference Style: APA
- Recommended for : Student Researchers
- NGN 3000
ABSTRACT
The ascorbic acid content of mineral ascorbate and six brands of ascorbic acid tablets marketed in Zaria with brand names Calcium ascorbate, Ascorbion, Emvit C, Ascorvite, Topcee, Bioracee and Sofa C respectively were comparatively evaluated using four methods. These include titrimetric method of British pharmacopoiea 2009, sodium thiosulphate titrimetric method, Ultra violet spectrophotometric method employing stabilizers and a newly developed 2,4- dinitrophenyl hydrazine method. The developed method was validated and the analyte showed an absorption maxima at 527nm and a percentage recovery of 97.4%. Beer‘s law was obeyed in the concentration range of 5ug to 25ug/ml, giving a regression equation of y= 0.041x + 0.032 and a correlation coefficient of 0.9910. The percentage content of ascorbic acid in Calcium ascorbate, Ascorbion, EmvitC, Ascorvite, Topcee, Bioracee, and SofaC in the Ultra violet spectroscopy method using stabilizers were 108.2%, 29.7%, 26.3%, 33%, 66.7%, 46.7%, 27.948% respectively. The values obtained from the sodium thiosulphate titrimetric method were 95.6%, 98.30%, 101.90%, 94.86%, 94.18%, 98.89% and 100.02% respectively. The results obtained from the B.P 2009 titrimetric method were 100.58%, 102.49%, 108.51%, 100.12%, 79.29%, 102.05% and 104.84% respectively, while that of the modified 2,4-dinitrophenyl hydrazine method were 100.47%, 101.99%, 107.898%, 99.83%%, 78.02%, 101.97%, 104.96% respectively. These results obtained showed that the UV spectrophotometric method gave values below the normal range. The values from the sodium thiosulphate titrimetric method was within the normal range but does not compare favourably with the official method, whereas the values for the modified 2,4 dinitrophenylhydrazine method and that of the B.P 2009 titrimetric method were both within the normal range and compared favourably with each other. Both results subjected to Student‘s T-testing showed no significant difference at P value 95% confidence interval (p=0.05). The B.P 2009 titrimetric method showed that there is one substandard product, which is Sofa C on the basis that it has a percent label claim not within 90±5%. The findings of this work further showed that the newly modified method can be used as a substitute for the official method.
Related Project Materials
THE ROLE OF EARLY CHILDHOOD EDUCATION IN PROMOTING PHYSICAL ACTIVITY
ABSTRACT: The role of early childhood education in promoting physical activity...
ASSESSMENT OF TELEVISION BROADCASTING, REALITY TV SHOWS AND MORAL DEVELOPMENT OF YOUTHS IN NIGERIA
Background of the study
A film, also called a movie or motion picture is a series of still or moving images using animat...
AN INVESTIGATION ON THE EFFORT OF GOVERNMENT AND THE MANAGEMENT OF SECURITY PROBLEMS IN NIGERIA
Background of the study
After the civil war that broke out in 1970 in Nigeria, the country's security situation has...
A CRITICAL EXAMINATION OF THE DEVELOPMENT OF VOCATIONAL EDUCATION CURRICULA FOR CAREERS IN GREEN ENGINEERING
ABSTRACT: A critical examination of the development of vocational education curricula for careers in green engineering is essential for prepar...
THE INFLUENCE OF DIGITAL TRANSFORMATION ON SUPPLY CHAIN MANAGEMENT
THE INFLUENCE OF DIGITAL TRANSFORMATION ON SUPPLY CHAIN MANAGEMENT
The study aims to: (1) analyze the impact of digital transformation on...
THE IMPACT OF HUMAN CAPITAL ON ECONOMIC GROWTH IN NIGERIA
EXCERPT FROM THE STUDY
According to Oyinlola and Adeyemi (2014) human capital development refers to the acquired and use...
DESIGN AND IMPLEMENTATION OF AN ONLINE CAMPUS OPINION POLL SYSTEM (A CASE STUDY OF UNIVERSITY OF ABUJA)
ABSTRACT
The paper aims at designing and implementing a simple and concise system that collects opinions of university s...
CHRISTIAN PARTICIPATION IN POLITICS: A MORAL CONCERN IN CONTEMPORARY NIGERIA
EXCERPT FROM THE STUDY
As we think upon the subject of Christians and politics it may seem odd to many that we would put...
EXAMINING THE ATTITUDES OF UNDERGRADUATE YOUTHS TOWARD DEMOCRATIC VALUES AND ITS IMPLICATYION ON SOCIAL STUDIES EDUCATION
ABSTRACT
This research work sought to assess the attitude of undergraduate youths toward democratic val...
THE ROLE OF VOCATIONAL EDUCATION IN PROMOTING SUSTAINABLE AGRICULTURAL PRACTICES
ABSTRACT: The role of vocational education in promoting sustainable agricultural practices is crucial for fostering environmentally friendly f...
