0704-883-0675     |      dataprojectng@gmail.com

COMPARATIVE EVALUATION OF THE ASCORBIC ACID CONTENT OF MINERAL ASCORBATE AND ASCORBIC ACID TABLETS MARKETED IN ZARIA

  • Project Research
  • 1-5 Chapters
  • Abstract : Available
  • Table of Content: Available
  • Reference Style: APA
  • Recommended for : Student Researchers
  • NGN 3000

ABSTRACT

The ascorbic acid content of mineral ascorbate and six brands of ascorbic acid tablets marketed in Zaria with brand names Calcium ascorbate, Ascorbion, Emvit C, Ascorvite, Topcee, Bioracee and Sofa C respectively were comparatively evaluated using four methods. These include titrimetric method of British pharmacopoiea 2009, sodium thiosulphate titrimetric method, Ultra violet spectrophotometric method employing stabilizers and a newly developed 2,4- dinitrophenyl hydrazine method. The developed method was validated and the analyte showed an absorption maxima at 527nm and a percentage recovery of 97.4%. Beer‘s law was obeyed in the concentration range of 5ug to 25ug/ml, giving a regression equation of y= 0.041x + 0.032 and a correlation coefficient of 0.9910. The percentage content of ascorbic acid in Calcium ascorbate, Ascorbion, EmvitC, Ascorvite, Topcee, Bioracee, and SofaC in the Ultra violet spectroscopy method using stabilizers were 108.2%, 29.7%, 26.3%, 33%, 66.7%, 46.7%, 27.948% respectively. The values obtained from the sodium thiosulphate titrimetric method were 95.6%, 98.30%, 101.90%, 94.86%, 94.18%, 98.89% and 100.02% respectively. The results obtained from the B.P 2009 titrimetric method were 100.58%, 102.49%, 108.51%, 100.12%, 79.29%, 102.05% and 104.84% respectively, while that of the modified 2,4-dinitrophenyl hydrazine method were 100.47%, 101.99%, 107.898%, 99.83%%, 78.02%, 101.97%, 104.96% respectively. These results obtained showed that the UV spectrophotometric method gave values below the normal range. The values from the sodium thiosulphate titrimetric method was within the normal range but does not compare favourably with the official method, whereas the values for the modified 2,4 dinitrophenylhydrazine method and that of the B.P 2009 titrimetric method were both within the normal range and compared favourably with each other. Both results subjected to Student‘s T-testing showed no significant difference at P value 95% confidence interval (p=0.05). The B.P 2009 titrimetric method showed that there is one substandard product, which is Sofa C on the basis that it has a percent label claim not within 90±5%. The findings of this work further showed that the newly modified method can be used as a substitute for the official method.




FIND OTHER RELATED TOPICS


Related Project Materials

ASSESSMENT OF THERAPEUTIC RECREATIONAL SPACES IN ORTHOPAEDIC HOSPITALS IN MINNA, NIGER STATE

ABSTRACT

There is a growing interest about the impact of the physical environment on the recovery process of patients among health care p...

Read more
EFFECT OF TWITTER BAN ON HUMANITARIAN SERVICE AND SOCIAL SUPPORT

ABSTRACT

The aim of this study is to examine the effect of twitter ban on humanitarian services and soc...

Read more
THE IMPACT OF MARKETING PLANNING AND CONTROL IN MANUFACTURING COMPANY

ABSTRACT

This research study outlines the impact of marketing planning and control in manufacturing com...

Read more
EFFECTS OF ANALYTIC AND CREATIVE PROBLEM-SOLVING ON INTEREST AND PERFORMANCE IN MATHEMATICS AMONG SENIOR SECONDARY SCHOOL STUDENTS

ABSTRACT

This study investigated the effects of analytic and creative problem-solving on Interest and Performance in Mathematics among Se...

Read more
APPLICATION OF BUILDING SURVEY FOR MAINTENANCE OF BUILDING IN NIGERIA

Abstract

This research project present the application of building survey for maintenance of build...

Read more
THE EFFECT OF TRAINING AND DEVELOPMENT ON EMPLOYEE PERFORMANCE (A CASE STUDY OF ROSEMORE HOTELS UYO)

Abstract

This study, sought to determine the impact of training on staff performance using RoseMore Hot...

Read more
AN ASSESSMENT OF CONFLICT MANAGEMENT IN AN ORGANIZATION

Abstract

This research work aimed at investigating the assessment of managing conflict in organization especially that o...

Read more
AN ASSESSMENT OF FINANCIAL STATEMENT AND ITS USEFULNESS IN ASSESSING THE PERFORMANCE OF AN ORGANIZATION

Background Of Study

A farmer who planted corps expects results, just as a student who waits for an exam does. The same m...

Read more
PERCIEVED INFLUENCE OF SMARTPHONE ON THE ACADEMIC PERFORMANCE OF UNIVERSITY STUDENTS

Background to the study

Information simply is that which informs, that from which data can be derived....

Read more
THE ROLE OF GOVERNMENTAL ACCOUNTANTS IN PUBLIC FINANCE MANAGEMENT

THE ROLE OF GOVERNMENTAL ACCOUNTANTS IN PUBLIC FINANCE MANAGEMENT

Abstract

This research explores the critical role of governme...

Read more
Share this page with your friends




whatsapp