ANTIMICROBIAL PROPERTY OF THE HEXANE EXTRACT FROM THE PODS OF ACACIA NILOTICA (L.) DEL. (MIMOSACEAE)
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- Recommended for : Student Researchers
- NGN 3000
ABSTRACT
Acacia niloticais a multipurpose plant belonging to the family Mimosaceae. Commonly known as Prickly acacia in English and Bagaruwa in Hausa, It has medicinal properties which include antimalaria, antimicrobial, anti-inflammatory, anticancer, etc. Traditionally, the pods are used for stomach disorder, foot and mouth disease, sore throat, dysentery, among others. This research was aimed at isolating from the pod of this plant and testing for its antimicrobial activity which will justify the claim for its usage. The pods were extracted using n-hexane and the extract was subjected to column chromatography which afforded a compound tagged CY2 which was analysed by spectroscopical means and suggested to be Pentacosane-dioic acid. Antimicrobial studies of the crude extract and the isolated compound against some pathogens were conducted and compared with standard drugs (Ciprofloxacin and Fluconazole). The result showed that the pod have antimicrobial activities, five bacterial strains (Staphylococcus aureus, Strptococcuspyrogenes, Eschericia coli, Shegiliadysenteriae, Salmonella typhi,) and one fungal strain (Candida albicans) were susceptible to both the crude extract and the isolated compound, The isolated compound tend to have a higher activity compared to the crude extract but not as potent as the control drugs used which showed better activity among all the microbes used. A bacteria strain (Corynebactoriumulcerans) and a fungal strain (Candida krusei) among the test organisms tend to be resistant to the crude extract as well as the isolated compound.
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