EFFECT OF EARLY LIFE EXPOSURE TO AIR POLLUTION ON DEVELOPMENT OF CHILDHOOD ASTHMA
- Project Research
- 1-5 Chapters
- Qualitative
- Content
- Abstract : Available
- Table of Content: Available
- Reference Style: APA
- Recommended for : Student Researchers
- NGN 3000
ABSTRACT
There is increasing recognition of the importance of early environmental exposures in the development of childhood asthma. Outdoor air pollution is a recognized asthma trigger, but it is unclear whether exposure influences incident disease. We investigated the effect of exposure to ambient air pollution in utero and during the first year of life on risk of subsequent asthma diagnosis in a population-based nested case-control study. The study assessed all children born in southwestern British Columbia in 1999 and 2000 (n = 37,401) for incidence of asthma diagnosis up to 34 years of age using outpatient and hospitalization records. Asthma cases were age- and sex-matched to five randomly chosen controls from the eligible cohort. We estimated each individual’s exposure to ambient air pollution for the gestational period and first year of life using high-resolution pollution surfaces derived from regulatory monitoring data as well as land use regression models adjusted for temporal variation. We used logistic regression analyses to estimate effects of carbon monoxide, nitric oxide, nitrogen dioxide, particulate matter. A total of 3,482 children (9%) were classified as asthma cases. We observed a statistically significantly increased risk of asthma diagnosis with increased early life exposure to CO, NO, NO2, PM10, SO2, and black carbon and proximity to point sources. Traffic-related pollutants were associated with the highest risks: adjusted odds ratio = 1.08 (95% confidence interval, 1.041.12) for a 10-microg/m3 increase of NO, 1.12 (1.071.17) for a 10-microg/m3 increase in NO2, and 1.10 (1.061.13) for a 100-microg/m3 increase in CO. These data support the hypothesis that early childhood exposure to air pollutants plays a role in development of asthma.
Related Project Materials
EFFECTS OF EXPOSURE TO CONTEXT CLUES ON ENGLISH VOCABULARY DEVELOPMENT OF JUNIOR SECONDARY II STUDENTS
ABSTRACT
An area that brings problem continuously to second language (L2) learners of English is vocabulary development. Exposing words t...
THE STATISTICAL ANALYSIS OF THE EXPENDITURE AND INCOME OF NIGERIA IN RELATION TO POVERTY
Abstract
This study is on the statistical analysis of the expenditure and income of Nigeria in relation to poverty...
THE ROLE OF MICRO-FINANCE BANKS IN THE DEVELOPMENT OF RURAL AREAS
ABSTRACT
The role of micro-finance banks in the development of rural areas using Oko Micro-Finance...
REAL ESTATE INVESTMENT AND ITS ASSOCIATED CHALLENGES IN NIGERIA
ABSTRACT
The study provides an overview of real estate investment in Nigeria, the study has the following objectives,&nb...
THE IMPACT OF MANAGEMENT SUPPORT ON EMPLOYEE MOTIVATION
Abstract: THE IMPACT OF MANAGEMENT SUPPORT ON EMPLOYEE MOTIVATION
Objective: This stud...
PERCEPTION OF UNDERGRADUATE STUDENTS IN NIGERIAN UNIVERSITIES ABOUT WHATSAPP SOCIAL MEDIA AS A TEACHING AND LEARNING TOOL
Background Of The Study
Internet technologies have impacted how individuals generate and distribu...
PROBLEMS OF TEACHING AGRICULTURAL SCIENCE IN JUNIOR SECTIONS OF SECONDARY SCHOOLS
Abstract
Recently various members of the society have raised an alarm on the low standard of education in Nigeria,...
DESIGN AND IMPLEMENTATION OF HEALTH CARE REMINDER APPLICATION
ABSTRACT
Patients on constant medication usually find difficulty in remembering the particular time their prescription is going to finish...
THE IMPACT OF ACCOUNTING ON ORGANIZATION EFFECTIVENESS A CASE STUDY OF THE FEDERAL PAY OFFICE
ABSTRACT
The need for keeping prompt and accurate record of transaction in the government services of the receipt and di...
EVALUATION OF THE GASTROPROTECTIVE AND SUB-CHRONIC TOXICITY OF METHANOL STEM BARK EXTRACT OF XIMENIA AMERICANA LINN (OLACACEAE) IN MALE WISTAR RATS
Abstract
Ximenia americana is a plant used traditionally in northern parts of Nigeria for treatment of leprotic ulcers and mouth ulcers i...
