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1. SERUM LIPID PROFILE OF AFRICA MESQUITE TREE PART EXTRACT IN RAT

65 Student Researchers

ABSTRACT

This study investigates the lipid-modulating effects of extracts from different parts of the African mesquite tree (Prosopis africana) in a rat model. The experiment employed a randomized controlled trial design with four groups: a control group and groups receiving extracts from leaves, bark, and pods of the mesquite tree. Baseline characteristics including body weight, serum cholesterol, triglycerides, HDL, and LDL levels were similar acr...

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2. CHRONIC TOXICITY EXTRACTION OF AFRICAN MESQUITE TREE PART EXTRACT IN RAT

65 Student Researchers

ABSTRACT

This study investigated the chronic toxicity of African Mesquite tree (Prosopis africana) extracts in Wistar rats, focusing on biochemical, hematological, and histopathological effects. The extracts were administered at doses of 100 mg/kg, 300 mg/kg, and 600 mg/kg over a 90-day period. Biochemical analyses indicated significant dose-dependent increases in liver function markers (ALT, AST, ALP, and bilirubin) and kidney function markers (ure...

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3. THE EFFECT OF IONIZING RADIATION ON THE HIPPOCAMPUS OF THE BRAIN

65 Student Researchers

CHAPTER ONE

INTRODUCTION

1.1 Background of the study

The hippocampus, a region situated within the medial temporal lobe of the brain, plays a critical role in various cognitive functions, including memory formation and spatial navigation. Given its sensitivity to various environmental factors and stressors, the h...

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4. PHYSIOCHEMICAL PROPERTIES OF SACHET WATER IN ABA

65 Student Researchers Quantitative

ABSTRACT

In spite of the varying levels of contamination widely reported, sachet water is still well accepted. This study therefore assessed social perception of people on the most popular sachet water brands, conducted sensory evaluation, quality certification and packaging and storage quality evaluation of sachet water samples. It also assessed the Physico-chemical and coliforms count of popular brands using standard laboratory procedures. For the study, two study...

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5. EFFECT OF IONIZING RADIATION ON THE KIDNEY (A CASE STUDY OF WINTER RAT)

65 Student Researchers

Background of the study

The effect of ionizing radiation on biological systems has been a subject of extensive research, particularly concerning its implications on various organs within the body. Among these organs, the kidney holds significant importance due to its role in maintaining homeostasis, regulating blood pressure, and filtering metabolic waste from the bloodstream. This comprehensive introduction delves into the intricate relationship be...

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6. IN SILICO EVALUATION ON THE INTERACTION BETWEEN KETONE BODIES AND OBESITY-ASSOCIATED PROTEINS

65 Student Researchers Qualitative

Background of study

Obesity, has been a pre-existing problem afore time but has been recognized as a global pandemic since the 21st century (Natalia, et al., 2021). Aronne, 2002 defines obesity as the anomalous, irregular or disproportionate gain of weight as a result of fat buildup in the body which adversely leads to the risk of several health related problems such as hypertension, type 2 diabetes, cardiovascular diseases and certain cancer types amongst others (Aronne, 2002; Nata...

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7. MOLECULAR CHARACTERIZATION OF PATHOGENIC ESCHERICHIA COLI IN READY-TO-EAT GAME MEAT AND FRESH PRODUCE FROM SOUTHWESTERN REGION OF NIGERIA

65 Student Researchers Qualitative

ABSTRACT

The consumption of ready-to-eat (RTE) game meat and fresh produce has increased and it serves as a very important part of human diet. Foodborne diseases linked to contaminated RTE game meat and fresh produce is a public health concern. This study investigated the pathogenic E. coli in these RTE foods sold in various cities in south western, Nigeria. The identification of E. coli were performed using sorbitol MacConkey agar (SMAC) and molecular characterization of virulence...

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8. MODULATORY EFFECT OF METFORMIN AND ARTEMETHER-LUMEFANTRINE ON BLOOD COAGULATION IN DIABETIC MICE CO-INFECTED WITH MALARIA

65 Student Researchers Qualitative

ABSTRACT

Blood coagulation is a process describing conversion of soluble materials within the blood into an insoluble gel that plugs injury/break site within blood vessels; this process requires regulation. Diabetes mellitus is a metabolic disorder characterized by hyperglycemia, defectiveness of insulin hormone has been found to have an increased risk of coagulation and can lead to cardiovascular disorders. Malaria is a disease caused by plasmodium parasite, when the parasite enter...

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9. EFFECT OF Phyllanthus amarus AND N-HEXADECANOIC ACID ON BLOOD COAGULATION PARAMETERS OF LIPOPOLYSACCHARIDE-INDUCED INFLAMMATION IN WISTAR RATS

65 Student Researchers Qualitative

ABSTRACT

Blood clotting is a complex sequence of processes involving multiple proteins (factors) that must operate in a specific order to create a clot. The procedure is rapid and effective, but it must be monitored because uncontrolled clotting can lead to thrombosis. A shift in the balance of blood coagulation and coagulation inhibition, favoring either pro- or anticoagulation, can result in life-threatening thromboembolism or bleeding. This study evaluated the effect of ethanol P...

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10. EVALUATION OF HYDRAULIC PROPERTIES AND WATER TABLE FLUCTUATION OF GBAKO AQUIFER, NIGER STATE, NIGERIA

65 Student Researchers

Statement of Problem 

In the past 25 years, Gbako drainage basin has experienced an increase in groundwater exploitation by the rural population (Amadi et al., 2010). The fast growing population in the parts of the basin is connected to the high potential for agricultural production in the area which causes a serious water and population imbalance, compounding the problem of falling groundwater levels. The rapidly diminishing and poor quality surface water resource have forced...

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11. EFFECT OF GLYCEROL AND SHEA BUTTER ON THE PROPERTIES OF FILMS PRODUCED FROM CHITOSAN AND Borassus aethiopum STARCH COMPOSITES

65 Student Researchers

ABSTRACT

The concern in environmental waste management and toxicity of petroleum derived plastics has led to the search for renewable, nontoxic and biodegradable materials for packaging. Starch is the most studied and promising biopolymer for the production of biodegradable films, but this starch films have poor properties which can be improved by blending with other materials and plasticizers. Borassus aethiopum shoot starch locally known as “Muruci” is a promising film...

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12. DEVELOPMENT OF BIOSURFACTANTS-IRON OXIDE NANOPARTICLESBIOCHAR FORMULATION FOR REMEDIATION OF CRUDE OIL CONTAMINATED SOIL

65 Student Researchers

ABSTRACT

Biosurfactant-mediated degradation of contaminants is practical and safe environmental remediation agent. In addition, iron oxide nanoparticles and biochar are bioremediation agents with great potentials due to their strong adsorption capacity, microbial growth enhancement and chemical inertness. Therefore, a combination of biosufactant, iron oxide nanoparticles and biochar could produce a very desirable and efficient alternative to conventional environmental treatment of c...

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13. CHARACTERIZATION OF UREASE OF BACTERIAL ISOLATES FROM CEMENT FOR CONCRETE ENHANCEMENT

65 Student Researchers

ABSTRACT

Ureases are a group of enzymes that hydrolyse urea producing carbon dioxide and ammonia. Urease producing bacteria have shown their importance in microbially induced calcium carbonate precipitation in the construction industry. This study focused on the characterization of bacterial isolates from cement for concrete enhancement. Two (2) bacterial isolates assigned codes CA (B) and CA (F) were isolated from cement samples using enrichment culture technique. The isolates were...

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14. BIOCALCIFICATION OF CONCRETE USING CARBONIC ANYHDRASE PRODUCED BY SOIL BACTERIAL ISOLATES

65 Student Researchers

ABSTRACT

Two (2) bacterial isolates obtained from Garima construction sites were named GARIMA (A) and (B), and code-named GA (A) and GA (B) respectively. They were screened for their carbonic anhydrase (CA) producing ability. Isolates GA (A) and GA (B) showed positive reaction to para-nitrophenylacetate (pNPA), producing yellow and peach/orange coloured colonies respectively. The isolates were used to produce the crude CA and the mean enzyme activity with standard error of mean for...

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15. THE OXIDATIVE STRESS STATUS OF RATS FED ON OIL BEAN SEED MEAL

65 Student Researchers

ABSTRACT

This study was on oxidative stress status of rat fed with Pentraclethra macrophylla, otherwise known as African oil bean seed oil in English or Ugba in Igbo. Sixteen male rats were distributed into four groups. 1 (control), then group 2, 3, and 4 as test groups. They were fed with their formulated meal (5%, 10%, 20% inclussions) for 28 days. Group 1 was the control and were fed with the normal feed, while group 2, 3 and 4 which were the test groups were fed with test feed f...

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16. THE EFFECT OF WATER EXTRACT OF COLA NITIDA POD ON LIPOPROTEIN CONCENTRATIONS OF ALBINO WISTAR RATS

65 Student Researchers

ABSTRACT

Cola nitida has been in use in the eastern parts of Nigeria for the management of certain ailments and as an aphrodisiac in the management of some sexual dysfunctions. However the effects of this extract in some health parameters in human objects have not been reported. This work, then, was aimed at investigating the effect of water extracts of kola pods on lipoprotein concentrations on albino wistar rats. Rats were used in this study and they were divided into several grou...

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17. THE EFFECT OF PTEROCARPUS MILDBREADII SEED ON PLASMA HDL CHOLESTEROL OF ALBINO RAT

65 Student Researchers

ABSRACT

This work was carried out to investigate the effects of pterocarpus mildbreadii seed on the HDL- level of albino rats.High density lipoprotein(HDL) is a fraction of cholesterol,which helps to transport cholesterol from peripheral of cell to the liver.High density lipoprotein is carried out to investigate cardio vascular diseases.Fresh oha seed (pterocarpus mildbreadii seed) was collected from Amokwe in udi local government Area Enugu state. They were dried at room temperatur...

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18. THE EFFECT OF ETHANOL EXTRACT OF DESMODIUM VELUTINUM STEM ON SOME MARKER EMZYME IN LIVER OF ALBINO WISTAR RATS

65 Student Researchers

Abstract

Present investigations were carried out on the effect of ethanol extract of Desmodium velutinum stem on some liver enzymes of albino wistar rats fed with 8 high fat from cow‟s brain. Twelve healthy albino wistar rats were divided into four groups. Group I rats were fed with balanced diet (normal feed, that is grower‟s mash) and tap water. Group II rats were fed with fat diet (cow‟s brain) (3.6g/day) alone. Group III rats received combined mixture of 70% fat diet (cow‟s brai...

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19. THE ANTI-INFLAMMATORY ACTIVITY OF Crateva adansonii DICHLOROMETHANE FRACTION.

65 Student Researchers

ABSTRACT

Crateva adansonii is a medicinal herb commonly used in parts of Africa because of the side effects of Non-Steroidal Anti-inflammatory Drugs (NSAID), like heart diseases and kidney failure. Inflammation is a major public heart issue in the world but treatment is becoming complex because of the side effects of antiinflammatory pharmaceutical drugs. Hence the need for alternative drug is highly required. This research work investigated the anti-inflammatory activity of dichlor...

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20. THE EFFECT OF N-HEXANE EXTRACT OF KOLA NITIDA BARK ON LIVER FUNCTION TEST OF ALBINO WISTAR RATS FED WITH HIGH FAT FROM COW‘S BRAIN

65 Student Researchers

ABSTRACT

Kola bark extract have been widely used in tradition medicine for thousand of year, it improves liver functions and provides protection against high fat fed metabolic rats. Present investigations were carried out on the hepatoprotective role of Kola bark extract meal treatment to high fat fed wistar rat. Healthy adult male wistar rats were divided into four groups Group I: rats were fed a standard Laboratory diet (groups match) (20g/rat/day), Group II: rats were fed a high-...

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21. PRELIMINARY INVESTIGATION ON EFFECTS OF BURANTASHI EXTRACT ON LIVER ENZYMES OF AIBINO MALE AND FEMALE WHISTAR RATS.

65 Student Researchers

ABSTRACT

This work was carried out to investigate the effects of Burantashi extract on liver enzymes of albino male and female whistar rats. Burantashi is a popular seasoning agent to barbecued meat (suya) in Nigeria,mostly found in the northern part of the Nigeria. Liver Enzymes are those enzymes that plays important role in the liver both in function and regulation. Erectile dysfunction (ED) is defined as the consistent or recurrent inability of a man to attain or maintain penile...

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22. PRELIMINARY INVESTIGATION ON EFFECTS OF BURANTASHI EXTRACT ON LIPOPROTEINS OF ALBINO MALE AND FEMALE WHISTAR RATS

65 Student Researchers

ABSTRACT

This work was carried out to investigate the effects of Burrantashi extracts on the lipoproteins Burantashi is a popular seasoning agent to barbecued meat (Suya) in Nigeria. Found in the northern parts of the country. Lipoproteins are the principal steroid or fat that is synthesized in the liver or intestines of animals. Erectile dysfunction (ED) is defined as the consistent or recurrent inability of a man to attain or maintain penile erection, sufficient for sexual activit...

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23. PHYTOCHEMICAL AND ANTI-INFLAMMATORY PROPERTIES OF METHANOL EXTRACT OF CRATEVA ADANSONII STEM BARK.

65 Student Researchers

ABSTRACT

 78 This research investigated the phytochemical and anti-inflammatory properties of methanol extract of Crateva adansonii stem bark. Although several edible and non-edible plants parts are used in inflammatory treatment, many record has been found of the use of Crateva adansonii stem bark. For this research, fresh stem bark of Crateva adansonii were collected from Asata village in Enugu State. The cuttings were authenticated at the Bioresource development centre. They...

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24. PHYTOCHEMICAL ANALYSIS AND THE ANTIINFLAMMATORY ACTIVITIES OF METHANOL EXTRACT OF CRATEVA ADANSONII

65 Student Researchers

ABSTRACT

Inflammation is a complex biological response of vascular tissue to harmful stimuli such as pathogen, damage cells or irritants. The urgency generated by in increased rate of stroke, atheroselerosis attributed to prolong use of cyclooxygenase-1 and 2 inhibitors have acceralated anti-inflammatory drug research over the last decade while synthetic pharmaceutical agents continued to dominate research, attention increasingly has been directed to natural products. These are ofte...

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25. NUTRITIONAL EVALUATION OF CEREAL AND LEGUME-BASED COMPLEMENTARY DIETS USED IN JOS, PLATEAU STATE

65 Student Researchers

ABSTRACT

Three multimix complementary diets were prepared from local foodstuffs i.e. maize (Zea mays), acha grain (Digitaria exilis) rice (Sativa oryza), sorghum (Sorgum bicolar), millet (Pennisatum typhoides), groundnut (Arachis hypogea), bambaranut (V-oadzeia subterranea), sesame (Sesamun indicum), carrots (Daucas carota), crayfish (Macrobrachuim Sp), garden egg (Solanum incanum), palm oil (Elaeis guinensis) and table salt (NaCl). The formulated diets were subjected to biochemical...

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