ANALYSIS OF PETROLEUM POLLUTION ON SERUM TRACE ELEMENT LEVEL, OXIDATIVE STATUS, AND BIOCHEMICAL INDICES IN THE RESIDENTS OF AN OIL HOST COMMUNITY (UGBEGUNGUN) IN DELTA STATE, NIGERIA
- Project Research
- 1-5 Chapters
- Abstract : Available
- Table of Content: Available
- Reference Style: APA
- Recommended for : Student Researchers
- NGN 3000
ABSTRACT
Activities of crude oil refining disrupt natural ecosystems which expose residents to environmental pollution, and consequently pose threat to their health and wellness. This study was aimed to analyze serum trace elements levels, oxidative status, and biochemical indices in the residents of an oil host community (Ugbegungun) in Delta State, Nigeria. A total of 100 subjects were recruited for this study which comprised 50 individuals from Ugbegungun and 50 individuals from Okada, a non-oil host community. Serum levels of lead (Pb), zinc (Zn), and cadmium (Cd) were evaluated using Atomic Absorption Spectrophotometer. Alanine transaminase (ALT), aspartate transaminase (AST) and alkaline phosphate (ALP) activities, and urea and creatinine were all evaluated with a commercially available enzymatic kit. The oxidative and antioxidative activities in the serum were estimated using the semi-automated spectrophotometric procedure. Enzyme-linked immunoassay was used to assess tumor necrotic factor-alpha (TNF-α) and 8-hydroxy-2-deoxyguanosine (8-OHdG). The results showed that serum levels of Pb, Cd, urea, creatinine, ALT, AST, ALP, malondialdehyde, TNF-α, and 8- OHdG were significantly higher (p<0.05) in female and male residents of Ugbegungun when compared with the female and male residents of the non-oil host community. The activities of superoxide dismutase, catalase, glutathione reductase, and total antioxidant capacity were significantly lower (p<0.05) in both female and male residents of Ugbegungun when compared with the residents of non-oil host community. In conclusion, the residents of an oil host community in Nigeria may be at high risk of kidney and liver toxicity through oxidative stress induction associated probably with heavy metal accumulation in the system.
Related Project Materials
INVESTMENT APPRAISAL TECHNIQUES AND THEIR APPLICATIONS BY FINANCE/ INVESTMENT HOUSES (A CASE OF UNION BANK PLC ENUGU URBAN)
ABSTRACT
Events over the years have shown that investors present and potential wants to invest their funds in anticipati...
DETERMINANTS OF DEPOSIT MONEY BANKS’ SHARE PERFORMANCE ON THE NIGERIAN STOCK MARKET
Abstract
Share price is a reflection of a company’s performance and investors’ expectations about the future...
THE EFFECT OF INTERNAL AUDIT ON THE PERFORMANCE OF PRIVATE FIRMS (A STUDY OF ANAMBRA MOTOR MANAUFACTURING COMPANY)
ABSTRACT
This study was carried out to examine the effect of internal audit on the performance of private f...
CO-OPERATIVE EDUCATION AND TRAINING IN TERTIARY INSTITUTIONS IN NIGERIA
EXCERPT FROM THE STUDY
Education is very important among all of us, the fact which is commonly nothing to deny among any...
APPRAISAL OF THE EFFECT OF PROPERTY MANAGEMENT ON PROPERTY VALUE
ABSTRACT
The property industry in Nigeria has been confronted with pressure due to population growth and urbanization ch...
INTERNATIONAL ACCOUNTING FOR GLOBAL SUPPLY CHAIN MANAGEMENT
INTERNATIONAL ACCOUNTING FOR GLOBAL SUPPLY CHAIN MANAGEMENT
ABSTRACT
This study aims to investigate (1) the role of accounting...
ASSESSING ECONOMIC AND WELFARE VALUES OF FISH IN THE LOWER NIGER RIVER
ABSTRACT
This study was intended to assess the economic and welfare values of fish in...
EMPLOYEES’ PERCEPTION ON MOTIVATION MECHANISM IN NIGERIA PUBLIC SERVICE
ABSTRACT
The focus of this study is to examine employees’ perception on motivation mechanism in N...
DESIGN AND IMPLEMENTATION OF AN OFFICE ENTERPRISE SYSTEM
Statement of Problem
Manual office systems always put pressure on people to be correct in all aspect of their wor...
ANTICONVULSANT STUDIES OF THREE SYNTHESIZED DICHLOROSUBSTITUTED PHENYL PROPANAMIDES AND THEIR ACTION ON VOLTAGE-GATED SODIUM CHANNELS (Nav1.6)
Abstract
The field of antiepileptic drug development has become dynamic, affording many promising research opportunities. Continued effor...
